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Research Article
Published Online: June 1982

Trazodone in depressed outpatients

Publication: American Journal of Psychiatry

Abstract

The authors compared the nontricyclic antidepressant trazodone with amitriptyline and placebo in a double-blind study of 202 unipolar depressed outpatients. Trazodone's clinical efficacy was similar to that of amitriptyline, with both active drugs producing significantly more clinical improvement than placebo. The incidence of anticholinergic side effects was lower for the patients taking trazodone than for those taking amitriptyline.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 803 - 806
PubMed: 7044154

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Published in print: June 1982
Published online: 1 April 2006

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