No access
Articles
Published Online: 12 July 2023
Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants
Kuldeep Kumar, Ph.D. [email protected], Claudia Modenato, Ph.D., Clara Moreau, Ph.D., Christopher R.K. Ching, Ph.D., Annabelle Harvey, M.Sc., Sandra Martin-Brevet, Ph.D., Guillaume Huguet, Ph.D., … Show All … , Martineau Jean-Louis, M.Sc., Elise Douard, M.Sc., Charles-Olivier Martin, Ph.D., Nadine Younis, M.Sc., Petra Tamer, M.Sc., Anne M. Maillard, Ph.D., Borja Rodriguez-Herreros, Ph.D., Aurélie Pain, M.Sc., 16p11.2 European Consortium, Simons Searchlight Consortium, Leila Kushan, M.Sc., Dmitry Isaev, M.Sc., Kathryn Alpert, M.Sc., Anjani Ragothaman, M.Sc., Jessica A. Turner, Ph.D., Lei Wang, Ph.D., Tiffany C. Ho, Ph.D., Lianne Schmaal, Ph.D., Ana I. Silva, Ph.D., Marianne B.M. van den Bree, Ph.D., David E.J. Linden, M.D., Michael J. Owen, M.D., Ph.D., Jeremy Hall, Ph.D., F.R.C.Psych., Sarah Lippé, Ph.D., Guillaume Dumas, Ph.D., Bogdan Draganski, M.D., Boris A. Gutman, Ph.D., Ida E. Sønderby, Ph.D., Ole A. Andreassen, M.D., Ph.D., Laura M. Schultz, Ph.D., Laura Almasy, Ph.D., David C. Glahn, Ph.D., Carrie E. Bearden, Ph.D., Paul M. Thompson, Ph.D., and Sébastien Jacquemont, M.D. [email protected] Show FewerAuthors Info & Affiliations
Publication: American Journal of Psychiatry
Abstract
Objective:
Copy number variants (CNVs) are well-known genetic pleiotropic risk factors for multiple neurodevelopmental and psychiatric disorders (NPDs), including autism (ASD) and schizophrenia. Little is known about how different CNVs conferring risk for the same condition may affect subcortical brain structures and how these alterations relate to the level of disease risk conferred by CNVs. To fill this gap, the authors investigated gross volume, vertex-level thickness, and surface maps of subcortical structures in 11 CNVs and six NPDs.
Methods:
Subcortical structures were characterized using harmonized ENIGMA protocols in 675 CNV carriers (CNVs at 1q21.1, TAR, 13q12.12, 15q11.2, 16p11.2, 16p13.11, and 22q11.2; age range, 6–80 years; 340 males) and 782 control subjects (age range, 6–80 years; 387 males) as well as ENIGMA summary statistics for ASD, schizophrenia, attention deficit hyperactivity disorder, obsessive-compulsive disorder, bipolar disorder, and major depression.
Results:
All CNVs showed alterations in at least one subcortical measure. Each structure was affected by at least two CNVs, and the hippocampus and amygdala were affected by five. Shape analyses detected subregional alterations that were averaged out in volume analyses. A common latent dimension was identified, characterized by opposing effects on the hippocampus/amygdala and putamen/pallidum, across CNVs and across NPDs. Effect sizes of CNVs on subcortical volume, thickness, and local surface area were correlated with their previously reported effect sizes on cognition and risk for ASD and schizophrenia.
Conclusions:
The findings demonstrate that subcortical alterations associated with CNVs show varying levels of similarities with those associated with neuropsychiatric conditions, as well distinct effects, with some CNVs clustering with adult-onset conditions and others with ASD. These findings provide insight into the long-standing questions of why CNVs at different genomic loci increase the risk for the same NPD and why a single CNV increases the risk for a diverse set of NPDs.
Get full access to this article
View all available purchase options and get full access to this article.
Supplementary Material
File (appi.ajp.20220304.ds001.pdf)
- Download
- 5.13 MB
Information & Authors
Information
Published In
History
Received: 5 April 2022
Revision received: 24 October 2022
Revision received: 4 March 2023
Accepted: 28 April 2023
Published online: 12 July 2023
Published in print: September 01, 2023
Keywords
Authors
Affiliations
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Claudia Modenato, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Clara Moreau, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Christopher R.K. Ching, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Annabelle Harvey, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Sandra Martin-Brevet, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Guillaume Huguet, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Martineau Jean-Louis, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Elise Douard, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Charles-Olivier Martin, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Nadine Younis, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Petra Tamer, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Anne M. Maillard, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Borja Rodriguez-Herreros, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Aurélie Pain, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
16p11.2 European Consortium, Simons Searchlight Consortium
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Leila Kushan, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Dmitry Isaev, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Kathryn Alpert, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Anjani Ragothaman, M.Sc.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Jessica A. Turner, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Lei Wang, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Tiffany C. Ho, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Lianne Schmaal, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Ana I. Silva, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Marianne B.M. van den Bree, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
David E.J. Linden, M.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Michael J. Owen, M.D., Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Jeremy Hall, Ph.D., F.R.C.Psych.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Sarah Lippé, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Guillaume Dumas, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Bogdan Draganski, M.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Boris A. Gutman, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Ida E. Sønderby, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Ole A. Andreassen, M.D., Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Laura M. Schultz, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Laura Almasy, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
David C. Glahn, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Carrie E. Bearden, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Paul M. Thompson, Ph.D.
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Centre de Recherche du CHU Sainte-Justine, University of Montreal, Montreal (Kumar, Harvey, Huguet, Jean-Louis, Douard, Martin, Younis, Tamer, Dumas, Jacquemont); Mila–Quebec AI Institute, University of Montreal, Montreal (Dumas); Laboratoire de Recherche en Neuroimagerie, Department of Clinical Neurosciences (Modenato, Martin-Brevet, Lippé, Draganski), and Service des Troubles du Spectre de l’Autisme et Apparentés (Maillard, Rodriguez-Herreros, Pain), Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; Human Genetics and Cognitive Functions, Institut Pasteur, and Université de Paris, CNRS UMR 3571, Paris (Moreau); Semel Institute for Neuroscience and Human Behavior, Departments of Psychiatry and Biobehavioral Sciences and Psychology, UCLA, Los Angeles (Kushan, Bearden); School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands (Silva, Linden); Centre for Neuropsychiatric Genetics and Genomics (Silva, van den Bree, Owen, Hall), Division of Psychological Medicine and Clinical Neurosciences, School of Medicine (van den Bree, Owen, Hall), and Neuroscience and Mental Health Innovation Institute (van den Bree, Linden, Hall), Cardiff University, Cardiff, U.K.; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany (Draganski); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Ching, Moreau, Thompson); Department of Biomedical and Health Informatics, Children’s Hospital of Philadelphia, Philadelphia (Schultz, Almasy); Lifespan Brain Institute, Children’s Hospital of Philadelphia and Penn Medicine, Philadelphia (Schultz, Almasy); Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (Almasy); Department of Psychiatry, Harvard Medical School, Boston, and Tommy Fuss Center for Neuropsychiatric Disease Research, Boston Children’s Hospital, Boston (Glahn); Department of Biomedical Engineering, Duke University, Durham, N.C. (Isaev); Department of Biomedical Engineering, Oregon Health and Science University, Portland (Ragothaman); Department of Psychology, Georgia State University, Atlanta (Turner); Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago (Alpert, Wang); Department of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus (Wang); Department of Psychiatry and Behavioral Sciences and Department of Psychology, Stanford University, Stanford (Ho); Orygen, National Centre of Excellence in Youth Mental Health, Parkville, Australia, and Centre for Youth Mental Health, University of Melbourne, Melbourne (Schmaal); NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, and University of Oslo, Oslo (Sønderby, Andreassen); Department of Medical Genetics, Oslo University Hospital, Oslo (Sønderby); K.G. Jebsen Centre for Neurodevelopmental Disorders, University of Oslo, Oslo (Sønderby, Andreassen); Department of Biomedical Engineering, Illinois Institute of Technology, Chicago (Gutman).
Notes
Send correspondence to Dr. Jacquemont ([email protected]) and Dr. Kumar ([email protected]).
Author Contributions
Dr. Kumar and Dr. Modenato contributed equally.
Competing Interests
Dr. van den Bree, Dr. Owen, and Dr. Hall have received grants from Takeda Pharmaceuticals. Dr. Owen has received a grant from Akrivia Health. Dr. Ching and Dr. Thompson have received a research grant from Biogen. Dr. Gutman is employed by and holds stock in Natera. The other authors report no financial relationships with commercial interests.
Funding Information
This research was supported by Calcul Québec (http://www.calculquebec.ca) and Compute Canada (http://www.computecanada.ca), the Brain Canada Multi-Investigator Research Initiative, NIMH (grant 1U01MH119690-01), the Canadian Institutes of Health Research (CIHR_400528), IVADO (Institut de Valorisation des Données) through the Canada First Research Excellence Fund, and Healthy Brains for Healthy Lives through the Canada First Research Excellence Fund. Dr. Jacquemont is a recipient of a Canada Research Chair in neurodevelopmental disorders and a chair from the Jeanne et Jean-Louis Levesque Foundation. The Cardiff CNV cohort was supported by the Wellcome Trust Strategic Award “DEFINE” and the National Centre for Mental Health with funds from Health and Care Research Wales (code 100202/Z/12/Z). The Centre Hospitalier Universitaire Vaudois (CHUV) cohort was supported by the Schweizerischer Nationalfonds (Swiss National Science Foundation) (Dr. Maillard, project PMPDP3 171331). Data from the UCLA cohort provided by Dr. Bearden (participants with 22q11.2 deletions or duplications and controls) were supported through grants from NIH (U54EB020403), NIMH (R01MH085953, R01MH100900, and R03MH105808), and the Simons Foundation Autism Research Initiative (SFARI Explorer Award). Dr. Modenato was supported by a Doc.Mobility grant from the Swiss National Science Foundation. Dr. Kumar was supported by the IVADO Postdoctoral Fellowship Program through the Canada First Research Excellence Fund. Dr. Ching and Dr. Thompson are supported in part by NIMH grants R01MH116147, R01MH123163, and R01MH121246, by the Milken Institute, and by the Baszucki Brain Research Fund. Dr. Sønderby is supported by the Research Council of Norway (grant 223273), the South-Eastern Norway Regional Health Authority (grant 2020060), the European Union’s Horizon 2020 Research and Innovation Programme (CoMorMent project, grant 847776), and Kristian Gerhard Jebsen Stiftelsen (SKGJ-MED-021). Dr. Draganski is supported by the Swiss National Science Foundation (project grants 32003B_135679, 32003B_159780, 324730_192755, and CRSK-3_190185), ERA NET iSEE project, the Swiss Personalized Health Network SACR project, and the Leenaards Foundation. The Laboratoire de Recherche en Neuroimagerie receives support from the Roger De Spoelberch and Partridge Foundations.
Metrics & Citations
Metrics
Citations
Export Citations
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.
For more information or tips please see 'Downloading to a citation manager' in the Help menu.
To download the citation to this article, select your reference manager software.
There are no citations for this item
View Options
Get Access
Login options
Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.
Personal login Institutional Login Open Athens loginPurchase Options
Purchase this article to access the full text.
PPV Articles - American Journal of Psychiatry
Not a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).