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Abstract

Objective: The authors investigated the role of genetic factors in 35% CO2-induced panic attacks.Method: Ninety twins recruited from general population were challenged with one-vital capacity inhalations of 35% CO2–65% O2. Probandwise concordance rates were calculated and rates compared for monozygotic and for dizygotic twins.Results: A significantly higher concordance was found for 35% CO2-induced panic attacks among monozygotic than dizygotic twins (55.6% versus 12.5%).Conclusions: These results suggest a relevant role of genetic factors in 35% CO2-induced panic attacks. Am J Psychiatry 1998; 155: 1184-1188

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 1184 - 1188
PubMed: 9734540

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Published online: 1 September 1998
Published in print: September 1998

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Giampaolo Perna, M.D., Ph.D.
Daniela Caldirola, M.D.
Daniela Di Bella, M.D.

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