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Published Online: 1 August 1999

Olanzapine for Psychosis in Patients With Parkinson's Disease With and Without Dementia

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine. Eight subjects had dementia. Six subjects (29%) discontinued treatment prematurely because of drowsiness. Delusions and hallucinations improved significantly, and 80% were rated as much or very much improved. There was no worsening of parkinsonism or cognition.

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Pages: 392 - 394
PubMed: 10440017

History

Published online: 1 August 1999
Published in print: August 1999

Authors

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D. Aarsland, M.D., Ph.D.
Received October 9, 1998; revised December 7, 1998; accepted January 14, 1999. From the Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, and the Department of Neurology, Central Hospital of Rogaland, Stavanger, Norway. Address correspondence to Dr. Aarsland, Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, P.O. Box 1163 Hillevåg, 4004 Stavanger, Norway. e-mail: [email protected]
J. P. Larsen, M.D., Ph.D.
Received October 9, 1998; revised December 7, 1998; accepted January 14, 1999. From the Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, and the Department of Neurology, Central Hospital of Rogaland, Stavanger, Norway. Address correspondence to Dr. Aarsland, Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, P.O. Box 1163 Hillevåg, 4004 Stavanger, Norway. e-mail: [email protected]
N. G. Lim , M.D.
Received October 9, 1998; revised December 7, 1998; accepted January 14, 1999. From the Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, and the Department of Neurology, Central Hospital of Rogaland, Stavanger, Norway. Address correspondence to Dr. Aarsland, Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, P.O. Box 1163 Hillevåg, 4004 Stavanger, Norway. e-mail: [email protected]
E. Tandberg, M.D.
Received October 9, 1998; revised December 7, 1998; accepted January 14, 1999. From the Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, and the Department of Neurology, Central Hospital of Rogaland, Stavanger, Norway. Address correspondence to Dr. Aarsland, Section of Geriatric Psychiatry, Rogaland Psychiatric Hospital, P.O. Box 1163 Hillevåg, 4004 Stavanger, Norway. e-mail: [email protected]

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