The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 11
- Number 3
- August 1999
Windows to the Brain
Special Article
Publication date: 01 August 1999
Pages301–306In the past two decades, neuroscientific investigations such as postmortem and neuroimaging studies have revealed a variety of regional brain disturbances in major mental illnesses. These emerging findings are difficult to appreciate fully without a ...
https://doi.org/10.1176/jnp.11.3.301Publication date: 01 August 1999
Pages307–314Clinical correlates of violent behavior are known, but the underlying mechanisms are not well understood. This article reviews recent progress in the understanding of such mechanisms involving complex interactions between genes, prenatal and perinatal ...
https://doi.org/10.1176/jnp.11.3.307Publication date: 01 August 1999
Pages315–327Adrenoleukodystrophy is an inherited X-linked peroxisomal disorder that preferentially affects the adrenal cortex, testes, and brain and may occur at almost any age. Psychiatric symptomatology is present in many of the adult-onset cases reported in the ...
https://doi.org/10.1176/jnp.11.3.315Regular Article
Publication date: 01 August 1999
Pages328–335Violent behavior in psychiatric patients may result in long-term hospitalization. There is no FDA-approved psychopharmacologic treatment for aggression. In this study, 20 chronically aggressive hospitalized patients were administered 1 week of placebo ...
https://doi.org/10.1176/jnp.11.3.328Publication date: 01 August 1999
Pages336–342The authors retrospectively assessed the effectiveness and side effects of risperidone used to treat behavioral disturbances in elderly outpatients with dementia. In 41 patients treated with risperidone 1.8±1.4 mg/day, there was complete suppression of ...
https://doi.org/10.1176/jnp.11.3.336Publication date: 01 August 1999
Pages343–348In 14 patients with myeloproliferative disorders associated with thrombocytosis, neurological and neuropsychological function were monitored prior to therapy with recombinant human interferon alpha (rIFN; dose 25 mU/week; range 10–35 mU/week) and after 3, ...
https://doi.org/10.1176/jnp.11.3.343Publication date: 01 August 1999
Pages349–353In light of the postulated role of thyrotropin-releasing hormone (TRH) as an endogenous antidepressant, 56 refractory mood-disordered patients and 34 healthy adult control subjects underwent lumbar puncture for cerebrospinal fluid (CSF) TRH analysis. By ...
https://doi.org/10.1176/jnp.11.3.349Publication date: 01 August 1999
Pages354–360After severe traumatic brain injury (TBI), sleep disturbances and changes in hormone secretion are frequently observed. Similarly, in depression, abnormalities of sleep and neuroendocrine regulation are common. To test the hypothesis that the changes in ...
https://doi.org/10.1176/jnp.11.3.354Publication date: 01 August 1999
Pages361–369Although cocaine use is a significant public health problem, there is a paucity of scientific data on long-term neurobehavioral effects. This study examined the dose-related association between chronic cocaine use and neurobehavioral performance. A ...
https://doi.org/10.1176/jnp.11.3.361Publication date: 01 August 1999
Pages370–379This study examined facial emotional expressions produced by schizophrenic (SZ), unipolar depressed (UD), and normal control (NC) right-handed adults. Hypotheses regarding right-hemisphere activation in UD and suppression in SZ were addressed, as well as ...
https://doi.org/10.1176/jnp.11.3.370Publication date: 01 August 1999
Pages380–386The authors studied the functional anatomy of the déjà vu (DV) experience in nonlesional temporal lobe epilepsy (TLE), using interictal fluorine-18 fluorodeoxyglucose PET in 14 patients with and 17 patients without DV. Several clinical conditions, such as ...
https://doi.org/10.1176/jnp.11.3.380Publication date: 01 August 1999
Pages387–391Many clinical and research findings converge to indicate that frontal lobe, basal ganglia, and related neuronal connections are primarily involved in human immunodeficiency virus (HIV) infection; frontal lobe, mainly the prefrontal cortex, has a ...
https://doi.org/10.1176/jnp.11.3.387Clinical and Research Reports
Publication date: 01 August 1999
Pages392–394Twenty-one patients with Parkinson's disease and psychosis were included in an open-label 8-week trial of olanzapine. Eight subjects had dementia. Six subjects (29%) discontinued treatment prematurely because of drowsiness. Delusions and hallucinations ...
https://doi.org/10.1176/jnp.11.3.392Publication date: 01 August 1999
Pages395–397This study examined the verbal and design fluency abilities of 25 subclinical obsessive-compulsive (OC) subjects and 27 noncompulsive control subjects. As hypothesized, the OC group showed reduced design fluency, and design fluency was also negatively ...
https://doi.org/10.1176/jnp.11.3.395Publication date: 01 August 1999
Pages398–400Obsessive musical tunes have been described in some cases of obsessive-compulsive disorder (OCD). The authors present 2 cases of patients with musical obsessions, including findings from functional brain imaging. Both patients, 1 with idiopathic OCD and 1 ...
https://doi.org/10.1176/jnp.11.3.398Neuropsychiatric Practice and Opinion
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