Lamotrigine-Induced Rash After Sun Exposure
Mr. A, a 42-year-old man with a diagnosis of schizoaffective disorder, bipolar type, was hospitalized in our clinic after a recurrence of his disorder that was induced by discontinuing his drug therapy. He received lamotrigine, 25 mg t.i.d., coadministrated with haloperidol, 20 mg b.i.d. His dose of lamotrigine was titrated gradually within a month. One year later, during Mr. A’s last hospitalization, his dose of lamotrigine was raised to 100 mg b.i.d., whereas his dose of haloperidol stayed the same. He showed a marked regulation of his mood fluctuations after his discharge, and he also experienced a relatively satisfying vocational and social adjustment. Three months later, an acute maculopapular rash with itching appeared, which subsided after his lamotrigine treatment was interrupted. The day before the rash appeared, he had been exposed to sunlight while doing agricultural work.Ms. B, a 30-year-old woman with a diagnosis of bipolar disorder type I (her most recent episode was manic), received lamotrigine as a prophylactic therapy. Her lamotrigine dose was titrated gradually within 1 month up to 100 mg b.i.d. Six months later, while her mood had a normal fluctuation, she developed an acute maculopapular rash with itching. The day before the rash appeared, she had been exposed to the light of a solarium. The rash subsided after her treatment with lamotrigine was discontinued.
References
Information & Authors
Information
Published In
History
Authors
Metrics & Citations
Metrics
Citations
Export Citations
If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.
For more information or tips please see 'Downloading to a citation manager' in the Help menu.
There are no citations for this item
View Options
View options
PDF/ePub
View PDF/ePubGet Access
Login options
Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.
Personal login Institutional Login Open Athens loginNot a subscriber?
PsychiatryOnline subscription options offer access to the DSM-5-TR® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.
Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).