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American Journal of Psychiatry

  • Volume 156
  • Number 12
  • December 1999

Editorial

Images In Neuroscience

Special Article

Publication date: 01 December 1999

Pages1850–1855

The author provides a preliminary framework for a systematic and dynamic understanding of dissociation through a consideration of the theories of Hughlings Jackson. Jackson’s ideas are briefly reviewed. He saw the proper scientific investigation of mental ...

https://doi.org/10.1176/ajp.156.12.1850

Publication date: 01 December 1999

Pages1856–1864

OBJECTIVE: A major change in DSM-IV is the inclusion in almost one-half of the diagnostic criteria sets of a clinical significance criterion, which requires that symptoms cause “clinically significant distress or impairment in social, occupational, or ...

https://doi.org/10.1176/ajp.156.12.1856

Regular Article

Publication date: 01 December 1999

Pages1865–1870

OBJECTIVE: There are few data addressing the outcome of ECT for persons over 75 years of age. In a prospective, multisite study, the authors compared characteristics and treatment outcomes of adult (59 and younger), young-old (60 to 74 years), and old-old ...

https://doi.org/10.1176/ajp.156.12.1865

Publication date: 01 December 1999

Pages1871–1878

OBJECTIVE: To determine whether there are abnormalities in the in vivo status of the serotonin type 2A (5-HT2A) receptor in late-life depression and Alzheimer’s disease, the authors used positron emission tomography (PET) to assess patients with these two ...

https://doi.org/10.1176/ajp.156.12.1871

Publication date: 01 December 1999

Pages1879–1886

OBJECTIVE: An extra portion of chromosome 21 in Down’s syndrome leads to a dementia in later life that is phenotypically similar to Alzheimer’s disease. Down’s syndrome therefore represents a model for studying preclinical stages of Alzheimer’s disease. ...

https://doi.org/10.1176/ajp.156.12.1879

Publication date: 01 December 1999

Pages1887–1894

OBJECTIVE: Studies examining suicide rates for U.S. women physicians and other U.S. women have found odds ratios as high as 4 to 1. Although such reports are controversial and are based on small groups (N=17 to 49 suicides), they are often cited as ...

https://doi.org/10.1176/ajp.156.12.1887

Publication date: 01 December 1999

Pages1895–1901

OBJECTIVE: The enzyme phosphoinositide-specific phospholipase C (PI-PLC) is a component of the phosphoinositide signal transduction system. Other components of this system have been found to be abnormal in adults and adolescents who have committed suicide,...

https://doi.org/10.1176/ajp.156.12.1895

Publication date: 01 December 1999

Pages1902–1908

OBJECTIVE: The most widely accepted hypothesis regarding the mechanism underlying lithium’s therapeutic efficacy in manic-depressive illness (bipolar affective disorder) is the inositol depletion hypothesis, which posits that lithium produces a lowering ...

https://doi.org/10.1176/ajp.156.12.1902

Publication date: 01 December 1999

Pages1909–1914

OBJECTIVE: This investigation evaluated the relationship between changes in thyroid indices and mood stability during lithium and carbamazepine prophylaxis for bipolar disorder. METHOD: In the first 2 years, 30 patients with bipolar mood disorder were ...

https://doi.org/10.1176/ajp.156.12.1909

Publication date: 01 December 1999

Pages1915–1923

OBJECTIVE: Generalized anxiety disorder might be better conceptualized as a prodrome, residual, or severity marker of major depression or other comorbid disorders than as an independent diagnosis. The authors questioned whether generalized anxiety ...

https://doi.org/10.1176/ajp.156.12.1915

Publication date: 01 December 1999

Pages1924–1930

OBJECTIVE: The authors examined the self-reported presence and treatment of current depressive disorder, posttraumatic stress disorder (PTSD), and alcohol-related disorder in a group of outpatient veterans. METHOD: Data were obtained from the Veterans ...

https://doi.org/10.1176/ajp.156.12.1924

Publication date: 01 December 1999

Pages1938–1943

OBJECTIVE: A dimensional approach to the characterization of delusions was used to examine the use of non-content-related descriptors of delusions in revealing differences across diagnostic categories and delusion types. METHOD: Interviews with 1,136 ...

https://doi.org/10.1176/ajp.156.12.1938

Publication date: 01 December 1999

Pages1944–1950

OBJECTIVE: Cognitive impairment is an important feature of schizophrenia and is correlated with functional outcome. However, psychiatry lacks a screening instrument that can reliably assess the types of cognitive impairment often seen in schizophrenia. ...

https://doi.org/10.1176/ajp.156.12.1944

Publication date: 01 December 1999

Pages1951–1957

OBJECTIVE: In a companion article in this issue of the Journal, the authors presented data suggesting that the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is sensitive to the types of impairments observed in schizophrenia, ...

https://doi.org/10.1176/ajp.156.12.1951

Publication date: 01 December 1999

Pages1958–1967

OBJECTIVE: The authors investigated the extent and distribution of signal hyperintensities on T2-weighted magnetic resonance imaging (MRI) of the brains of subjects with late-onset schizophrenia. METHOD: The study group consisted of 25 subjects with DSM-...

https://doi.org/10.1176/ajp.156.12.1958

Publication date: 01 December 1999

Pages1968–1975

OBJECTIVE: The goal of this study was to evaluate the effectiveness of involuntary outpatient commitment in reducing rehospitalizations among individuals with severe mental illnesses. METHOD: Subjects who were hospitalized involuntarily were randomly ...

https://doi.org/10.1176/ajp.156.12.1968

Clinical Case Conference

Images in Psychiatry

Brief Report

Publication date: 01 December 1999

Pages1983–1985

OBJECTIVE: Studies suggest a link between visual acuity and visual hallucinations in dementia, but links with specific eye pathologies have not been evaluated. METHOD: Fifty patients (20 with visual hallucinations, 30 without) with probable Alzheimer’s ...

https://doi.org/10.1176/ajp.156.12.1983

Publication date: 01 December 1999

Pages1989–1991

OBJECTIVE: The striatum (caudate and putamen) appears to be important in the pathogenesis of depression. Some studies show smaller than normal striatal structure volumes in depressed subjects. This study compared striatal volumes in depressed and ...

https://doi.org/10.1176/ajp.156.12.1989

Publication date: 01 December 1999

Pages1992–1993

OBJECTIVE: The purpose of this study was to assess the duration of periods of euthymia in patients with dysthymia. METHOD: All patients with dysthymia who came to the Center for Anxiety and Depression over a 10-month period (N=22) were interviewed by the ...

https://doi.org/10.1176/ajp.156.12.1992

Publication date: 01 December 1999

Pages1994–1995

OBJECTIVE: The purpose of this study was to examine the influence of traumatic grief on suicidal ideation. METHOD: The Beck-Kovacs Scale for Suicidal Ideation was administered to 76 young adult friends of suicide victims. RESULTS: Traumatic grief was ...

https://doi.org/10.1176/ajp.156.12.1994

Publication date: 01 December 1999

Pages1996–1997

OBJECTIVE: The authors’ goal was to examine whether the postpsychotic decline in full-scale IQ during adolescence for patients with childhood-onset schizophrenia is due to a dementing process or simply failure to acquire new information and skills. METHOD:...

https://doi.org/10.1176/ajp.156.12.1996

Publication date: 01 December 1999

Pages1998–2000

OBJECTIVE: The aim of the present study was to determine the rate of obsessive-compulsive disorder (OCD) in patients with first-episode schizophrenia. METHOD: Fifty patients consecutively hospitalized with first-episode psychosis who met DSM-IV criteria ...

https://doi.org/10.1176/ajp.156.12.1998

Book Forum: LITERATURE

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Book Forum: ART

Book Forum: GOOD AND EVIL

Letter to the Editor

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