American Journal of Psychiatry
- Volume 156
- Number 12
- December 1999
Editorial
Images In Neuroscience
Special Article
Publication date: 01 December 1999
Pages1850–1855The author provides a preliminary framework for a systematic and dynamic understanding of dissociation through a consideration of the theories of Hughlings Jackson. Jackson’s ideas are briefly reviewed. He saw the proper scientific investigation of mental ...
https://doi.org/10.1176/ajp.156.12.1850Publication date: 01 December 1999
Pages1856–1864OBJECTIVE: A major change in DSM-IV is the inclusion in almost one-half of the diagnostic criteria sets of a clinical significance criterion, which requires that symptoms cause “clinically significant distress or impairment in social, occupational, or ...
https://doi.org/10.1176/ajp.156.12.1856Regular Article
Publication date: 01 December 1999
Pages1865–1870OBJECTIVE: There are few data addressing the outcome of ECT for persons over 75 years of age. In a prospective, multisite study, the authors compared characteristics and treatment outcomes of adult (59 and younger), young-old (60 to 74 years), and old-old ...
https://doi.org/10.1176/ajp.156.12.1865Publication date: 01 December 1999
Pages1871–1878OBJECTIVE: To determine whether there are abnormalities in the in vivo status of the serotonin type 2A (5-HT2A) receptor in late-life depression and Alzheimer’s disease, the authors used positron emission tomography (PET) to assess patients with these two ...
https://doi.org/10.1176/ajp.156.12.1871Publication date: 01 December 1999
Pages1879–1886OBJECTIVE: An extra portion of chromosome 21 in Down’s syndrome leads to a dementia in later life that is phenotypically similar to Alzheimer’s disease. Down’s syndrome therefore represents a model for studying preclinical stages of Alzheimer’s disease. ...
https://doi.org/10.1176/ajp.156.12.1879Publication date: 01 December 1999
Pages1887–1894OBJECTIVE: Studies examining suicide rates for U.S. women physicians and other U.S. women have found odds ratios as high as 4 to 1. Although such reports are controversial and are based on small groups (N=17 to 49 suicides), they are often cited as ...
https://doi.org/10.1176/ajp.156.12.1887Publication date: 01 December 1999
Pages1895–1901OBJECTIVE: The enzyme phosphoinositide-specific phospholipase C (PI-PLC) is a component of the phosphoinositide signal transduction system. Other components of this system have been found to be abnormal in adults and adolescents who have committed suicide,...
https://doi.org/10.1176/ajp.156.12.1895Publication date: 01 December 1999
Pages1902–1908OBJECTIVE: The most widely accepted hypothesis regarding the mechanism underlying lithium’s therapeutic efficacy in manic-depressive illness (bipolar affective disorder) is the inositol depletion hypothesis, which posits that lithium produces a lowering ...
https://doi.org/10.1176/ajp.156.12.1902Publication date: 01 December 1999
Pages1909–1914OBJECTIVE: This investigation evaluated the relationship between changes in thyroid indices and mood stability during lithium and carbamazepine prophylaxis for bipolar disorder. METHOD: In the first 2 years, 30 patients with bipolar mood disorder were ...
https://doi.org/10.1176/ajp.156.12.1909Publication date: 01 December 1999
Pages1915–1923OBJECTIVE: Generalized anxiety disorder might be better conceptualized as a prodrome, residual, or severity marker of major depression or other comorbid disorders than as an independent diagnosis. The authors questioned whether generalized anxiety ...
https://doi.org/10.1176/ajp.156.12.1915Publication date: 01 December 1999
Pages1924–1930OBJECTIVE: The authors examined the self-reported presence and treatment of current depressive disorder, posttraumatic stress disorder (PTSD), and alcohol-related disorder in a group of outpatient veterans. METHOD: Data were obtained from the Veterans ...
https://doi.org/10.1176/ajp.156.12.1924Publication date: 01 December 1999
Pages1931–1937OBJECTIVE: Despite the increasing recognition of attention deficit hyperactivity disorder (ADHD) in adults, there is a paucity of controlled pharmacological trials. Recent reports have suggested the potential usefulness of cholinergic agents for ADHD. To ...
https://doi.org/10.1176/ajp.156.12.1931Publication date: 01 December 1999
Pages1938–1943OBJECTIVE: A dimensional approach to the characterization of delusions was used to examine the use of non-content-related descriptors of delusions in revealing differences across diagnostic categories and delusion types. METHOD: Interviews with 1,136 ...
https://doi.org/10.1176/ajp.156.12.1938Publication date: 01 December 1999
Pages1944–1950OBJECTIVE: Cognitive impairment is an important feature of schizophrenia and is correlated with functional outcome. However, psychiatry lacks a screening instrument that can reliably assess the types of cognitive impairment often seen in schizophrenia. ...
https://doi.org/10.1176/ajp.156.12.1944Publication date: 01 December 1999
Pages1951–1957OBJECTIVE: In a companion article in this issue of the Journal, the authors presented data suggesting that the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is sensitive to the types of impairments observed in schizophrenia, ...
https://doi.org/10.1176/ajp.156.12.1951Publication date: 01 December 1999
Pages1958–1967OBJECTIVE: The authors investigated the extent and distribution of signal hyperintensities on T2-weighted magnetic resonance imaging (MRI) of the brains of subjects with late-onset schizophrenia. METHOD: The study group consisted of 25 subjects with DSM-...
https://doi.org/10.1176/ajp.156.12.1958Publication date: 01 December 1999
Pages1968–1975OBJECTIVE: The goal of this study was to evaluate the effectiveness of involuntary outpatient commitment in reducing rehospitalizations among individuals with severe mental illnesses. METHOD: Subjects who were hospitalized involuntarily were randomly ...
https://doi.org/10.1176/ajp.156.12.1968Clinical Case Conference
Images in Psychiatry
Brief Report
Publication date: 01 December 1999
Pages1983–1985OBJECTIVE: Studies suggest a link between visual acuity and visual hallucinations in dementia, but links with specific eye pathologies have not been evaluated. METHOD: Fifty patients (20 with visual hallucinations, 30 without) with probable Alzheimer’s ...
https://doi.org/10.1176/ajp.156.12.1983Publication date: 01 December 1999
Pages1986–1988OBJECTIVE: This study investigated prefrontal cortex function in the manic state of bipolar disorder. METHOD: High-sensitivity [15O]H2O positron emission tomography and a word generation activation paradigm were used to study regional cerebral blood flow ...
https://doi.org/10.1176/ajp.156.12.1986Publication date: 01 December 1999
Pages1989–1991OBJECTIVE: The striatum (caudate and putamen) appears to be important in the pathogenesis of depression. Some studies show smaller than normal striatal structure volumes in depressed subjects. This study compared striatal volumes in depressed and ...
https://doi.org/10.1176/ajp.156.12.1989Publication date: 01 December 1999
Pages1992–1993OBJECTIVE: The purpose of this study was to assess the duration of periods of euthymia in patients with dysthymia. METHOD: All patients with dysthymia who came to the Center for Anxiety and Depression over a 10-month period (N=22) were interviewed by the ...
https://doi.org/10.1176/ajp.156.12.1992Publication date: 01 December 1999
Pages1994–1995OBJECTIVE: The purpose of this study was to examine the influence of traumatic grief on suicidal ideation. METHOD: The Beck-Kovacs Scale for Suicidal Ideation was administered to 76 young adult friends of suicide victims. RESULTS: Traumatic grief was ...
https://doi.org/10.1176/ajp.156.12.1994Publication date: 01 December 1999
Pages1996–1997OBJECTIVE: The authors’ goal was to examine whether the postpsychotic decline in full-scale IQ during adolescence for patients with childhood-onset schizophrenia is due to a dementing process or simply failure to acquire new information and skills. METHOD:...
https://doi.org/10.1176/ajp.156.12.1996Publication date: 01 December 1999
Pages1998–2000OBJECTIVE: The aim of the present study was to determine the rate of obsessive-compulsive disorder (OCD) in patients with first-episode schizophrenia. METHOD: Fifty patients consecutively hospitalized with first-episode psychosis who met DSM-IV criteria ...
https://doi.org/10.1176/ajp.156.12.1998