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American Journal of Psychiatry

  • Volume 156
  • Number 11
  • November 1999

Editorial

Images In Neuroscience

Special Article

Publication date: 01 November 1999

Pages1677–1685

OBJECTIVE: A new diagnosis can greatly influence scientific research, access to resources, and treatment selection in clinical practice. The authors review the historical evolution, rationale, empirical foundation, and clinical utility to date of the ...

https://doi.org/10.1176/ajp.156.11.1677

Publication date: 01 November 1999

Pages1686–1696

OBJECTIVE: The purpose of this study was to estimate and compare the effects of anti­psychotics—both the newer ones and the conventional ones—on body weight. METHOD: A comprehensive literature search identified 81 English- and non-English-language ...

https://doi.org/10.1176/ajp.156.11.1686

Regular Article

Publication date: 01 November 1999

Pages1697–1702

OBJECTIVE: Clinicians are under increasing pressure to transfer inpatients with anorexia nervosa to less intensive treatment early in their hospital course. This study identifies prognostic factors clinicians can use in determining the earliest time to ...

https://doi.org/10.1176/ajp.156.11.1697

Publication date: 01 November 1999

Pages1703–1708

OBJECTIVE: Obsessive-compulsive disorder (OCD) symptoms are common in people who are ill with bulimia nervosa. However, little is known about whether OCD symptoms persist after long-term recovery from bulimia. METHOD: Thirty-one female patients with ...

https://doi.org/10.1176/ajp.156.11.1703

Publication date: 01 November 1999

Pages1709–1719

OBJECTIVE: Abnormalities in prefrontal cortical γ-aminobutyric acid (GABA) neurotransmission may contribute to cognitive dysfunction in schizophrenia. The density of chandelier neuron axon terminals (cartridges) immunoreactive for the GABA membrane ...

https://doi.org/10.1176/ajp.156.11.1709

Publication date: 01 November 1999

Pages1720–1724

OBJECTIVE: There have been claims that schizophrenia is a disease of the limbic circuit and that the volume of the hippocampus and its content of neurons are low in schizophrenia. The fornix is a major pathway through which neurons project to and from the ...

https://doi.org/10.1176/ajp.156.11.1720

Publication date: 01 November 1999

Pages1725–1729

OBJECTIVE: There have been numerous reports of organic or structural abnormalities in the central nervous system (CNS) of patients with schizophrenia. Given that pathological conditions in the CNS are frequently reflected in the cell profiles of CSF, the ...

https://doi.org/10.1176/ajp.156.11.1725

Publication date: 01 November 1999

Pages1730–1735

OBJECTIVE: Studies of schizophrenia have not clearly defined handedness as a differentiating variable. Moreover, the relationship between thought disorder and anatomical anomalies has not been studied extensively in left-handed schizophrenic men. The ...

https://doi.org/10.1176/ajp.156.11.1730

Publication date: 01 November 1999

Pages1736–1743

OBJECTIVE: The authors assessed the presence and severity of depressive symptoms, as well as their associations with other clinical measures, in a group of mid- to late-life patients with schizophrenia who were not in a major depressive episode or ...

https://doi.org/10.1176/ajp.156.11.1736

Publication date: 01 November 1999

Pages1744–1750

OBJECTIVE: This study explored the relative efficacy of three different doses of clozapine. METHOD: Fifty patients who met Kane et al.’s criteria for treatment-refractory schizophrenia or schizoaffective disorder were studied. All subjects were randomly ...

https://doi.org/10.1176/ajp.156.11.1744

Publication date: 01 November 1999

Pages1751–1757

OBJECTIVE: Previous studies of smoking habits of schizophrenic patients have found rates as high as 88%. The authors report the smoking habits of all known schizophrenic patients within a discrete geographical area and compare them with the smoking habits ...

https://doi.org/10.1176/ajp.156.11.1751

Publication date: 01 November 1999

Pages1758–1764

OBJECTIVE: The opiate antagonist drug naltrexone has been shown in a few studies with limited sample sizes to be effective when combined with psychosocial therapies for the treatment of alcohol dependence. The goal of this study was to obtain additional ...

https://doi.org/10.1176/ajp.156.11.1758

Publication date: 01 November 1999

Pages1765–1770

OBJECTIVE: The changing effectiveness of a treatment program for dual-diagnosis patients was evaluated over a 2-year period with the use of a sequential study group design. METHOD: The treatment outcome of 179 consecutively enrolled patients with chronic ...

https://doi.org/10.1176/ajp.156.11.1765

Publication date: 01 November 1999

Pages1771–1779

OBJECTIVE: A deficit in serotonergic neurotransmission has been linked to impulsive behavior, as well as to disorders characterized by disinhibition. The present study tested the hypothesis that young men at high risk for alcoholism demonstrate greater ...

https://doi.org/10.1176/ajp.156.11.1771

Publication date: 01 November 1999

Pages1780–1786

OBJECTIVE: Acute stress disorder permits an early identification of trauma survivors who are at risk of developing chronic posttraumatic stress disorder (PTSD). This study aimed to prevent PTSD by an early provision of cognitive behavior therapy. ...

https://doi.org/10.1176/ajp.156.11.1780

Publication date: 01 November 1999

Pages1787–1795

OBJECTIVE: Childhood sexual abuse is very common in our society, but little is known about the long-term effects of abuse on brain function. The purpose of this study was to measure neural correlates of memories of childhood abuse in sexually abused women ...

https://doi.org/10.1176/ajp.156.11.1787

Publication date: 01 November 1999

Pages1796–1800

OBJECTIVE: The purpose of this study was to test the hypothesis that the prior experience of physical illness in childhood is associated with later experience of medically unexplained symptoms. METHOD: A nested case-control study was performed within a ...

https://doi.org/10.1176/ajp.156.11.1796

Clinical Case Conference

Images In Psychiatry

Brief Report

Publication date: 01 November 1999

Pages1808–1810

OBJECTIVE: This study examined the relation between peritraumatic dissociation and posttraumatic stress disorder (PTSD) in victims of motor vehicle accidents. METHOD: Victims of serious motor vehicle accidents (N=122) were assessed for peritraumatic ...

https://doi.org/10.1176/ajp.156.11.1808

Publication date: 01 November 1999

Pages1811–1813

OBJECTIVE: This study approaches the question of nature and nurture of dissociative phenomena. Within Cloninger’s concept of personality, character traits are thought to develop in response to environmental stimuli and conditions during childhood and ...

https://doi.org/10.1176/ajp.156.11.1811

Publication date: 01 November 1999

Pages1814–1816

OBJECTIVE: Interpersonal psychotherapy is a time-limited treatment initially developed to treat depression. It has not been studied for the treatment of anxiety disorders. METHOD: Interpersonal psychotherapy was modified and tested in a 14-week, open ...

https://doi.org/10.1176/ajp.156.11.1814

Publication date: 01 November 1999

Pages1817–1818

OBJECTIVE: This study aimed to replicate findings that neurocognitive capacity in schizophrenia is more predictive of acquisition of social skills than are symptoms. METHOD: Thirty-two hospitalized patients with chronic psychotic disorders were randomly ...

https://doi.org/10.1176/ajp.156.11.1817

Publication date: 01 November 1999

Pages1819–1821

OBJECTIVE: Pharmacologic prescriptions for anxiety disorders have changed significantly in the last decade. This article investigates whether psychosocial treatments, as reported by 362 subjects in the Harvard/Brown Anxiety Disorders Research Program from ...

https://doi.org/10.1176/ajp.156.11.1819

Publication date: 01 November 1999

Pages1822–1825

OBJECTIVE: d-Serine is a full agonist at the glycine site on the N-methyl-d-aspartate (NMDA) receptor. Previous administration of d-serine to schizophrenic patients taking nonclozapine antipsychotics improved positive, negative, and cognitive symptoms, ...

https://doi.org/10.1176/ajp.156.11.1822

Book Forum: CHANGES IN VALUES AND POLICIES

Book Forum: CHILD PSYCHIATRY

Book Forum: TORTURE AND TRAUMA

Book Forum: TREATMENT

Letter to the Editor

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