American Journal of Psychiatry
- Volume 156
- Number 11
- November 1999
Editorial
Images In Neuroscience
Special Article
Publication date: 01 November 1999
Pages1677–1685OBJECTIVE: A new diagnosis can greatly influence scientific research, access to resources, and treatment selection in clinical practice. The authors review the historical evolution, rationale, empirical foundation, and clinical utility to date of the ...
https://doi.org/10.1176/ajp.156.11.1677Publication date: 01 November 1999
Pages1686–1696OBJECTIVE: The purpose of this study was to estimate and compare the effects of antipsychotics—both the newer ones and the conventional ones—on body weight. METHOD: A comprehensive literature search identified 81 English- and non-English-language ...
https://doi.org/10.1176/ajp.156.11.1686Regular Article
Publication date: 01 November 1999
Pages1697–1702OBJECTIVE: Clinicians are under increasing pressure to transfer inpatients with anorexia nervosa to less intensive treatment early in their hospital course. This study identifies prognostic factors clinicians can use in determining the earliest time to ...
https://doi.org/10.1176/ajp.156.11.1697Publication date: 01 November 1999
Pages1703–1708OBJECTIVE: Obsessive-compulsive disorder (OCD) symptoms are common in people who are ill with bulimia nervosa. However, little is known about whether OCD symptoms persist after long-term recovery from bulimia. METHOD: Thirty-one female patients with ...
https://doi.org/10.1176/ajp.156.11.1703Publication date: 01 November 1999
Pages1709–1719OBJECTIVE: Abnormalities in prefrontal cortical γ-aminobutyric acid (GABA) neurotransmission may contribute to cognitive dysfunction in schizophrenia. The density of chandelier neuron axon terminals (cartridges) immunoreactive for the GABA membrane ...
https://doi.org/10.1176/ajp.156.11.1709Publication date: 01 November 1999
Pages1720–1724OBJECTIVE: There have been claims that schizophrenia is a disease of the limbic circuit and that the volume of the hippocampus and its content of neurons are low in schizophrenia. The fornix is a major pathway through which neurons project to and from the ...
https://doi.org/10.1176/ajp.156.11.1720Publication date: 01 November 1999
Pages1725–1729OBJECTIVE: There have been numerous reports of organic or structural abnormalities in the central nervous system (CNS) of patients with schizophrenia. Given that pathological conditions in the CNS are frequently reflected in the cell profiles of CSF, the ...
https://doi.org/10.1176/ajp.156.11.1725Publication date: 01 November 1999
Pages1730–1735OBJECTIVE: Studies of schizophrenia have not clearly defined handedness as a differentiating variable. Moreover, the relationship between thought disorder and anatomical anomalies has not been studied extensively in left-handed schizophrenic men. The ...
https://doi.org/10.1176/ajp.156.11.1730Publication date: 01 November 1999
Pages1736–1743OBJECTIVE: The authors assessed the presence and severity of depressive symptoms, as well as their associations with other clinical measures, in a group of mid- to late-life patients with schizophrenia who were not in a major depressive episode or ...
https://doi.org/10.1176/ajp.156.11.1736Publication date: 01 November 1999
Pages1744–1750OBJECTIVE: This study explored the relative efficacy of three different doses of clozapine. METHOD: Fifty patients who met Kane et al.’s criteria for treatment-refractory schizophrenia or schizoaffective disorder were studied. All subjects were randomly ...
https://doi.org/10.1176/ajp.156.11.1744Publication date: 01 November 1999
Pages1751–1757OBJECTIVE: Previous studies of smoking habits of schizophrenic patients have found rates as high as 88%. The authors report the smoking habits of all known schizophrenic patients within a discrete geographical area and compare them with the smoking habits ...
https://doi.org/10.1176/ajp.156.11.1751Publication date: 01 November 1999
Pages1758–1764OBJECTIVE: The opiate antagonist drug naltrexone has been shown in a few studies with limited sample sizes to be effective when combined with psychosocial therapies for the treatment of alcohol dependence. The goal of this study was to obtain additional ...
https://doi.org/10.1176/ajp.156.11.1758Publication date: 01 November 1999
Pages1765–1770OBJECTIVE: The changing effectiveness of a treatment program for dual-diagnosis patients was evaluated over a 2-year period with the use of a sequential study group design. METHOD: The treatment outcome of 179 consecutively enrolled patients with chronic ...
https://doi.org/10.1176/ajp.156.11.1765Publication date: 01 November 1999
Pages1771–1779OBJECTIVE: A deficit in serotonergic neurotransmission has been linked to impulsive behavior, as well as to disorders characterized by disinhibition. The present study tested the hypothesis that young men at high risk for alcoholism demonstrate greater ...
https://doi.org/10.1176/ajp.156.11.1771Publication date: 01 November 1999
Pages1780–1786OBJECTIVE: Acute stress disorder permits an early identification of trauma survivors who are at risk of developing chronic posttraumatic stress disorder (PTSD). This study aimed to prevent PTSD by an early provision of cognitive behavior therapy. ...
https://doi.org/10.1176/ajp.156.11.1780Publication date: 01 November 1999
Pages1787–1795OBJECTIVE: Childhood sexual abuse is very common in our society, but little is known about the long-term effects of abuse on brain function. The purpose of this study was to measure neural correlates of memories of childhood abuse in sexually abused women ...
https://doi.org/10.1176/ajp.156.11.1787Publication date: 01 November 1999
Pages1796–1800OBJECTIVE: The purpose of this study was to test the hypothesis that the prior experience of physical illness in childhood is associated with later experience of medically unexplained symptoms. METHOD: A nested case-control study was performed within a ...
https://doi.org/10.1176/ajp.156.11.1796Clinical Case Conference
Images In Psychiatry
Brief Report
Publication date: 01 November 1999
Pages1808–1810OBJECTIVE: This study examined the relation between peritraumatic dissociation and posttraumatic stress disorder (PTSD) in victims of motor vehicle accidents. METHOD: Victims of serious motor vehicle accidents (N=122) were assessed for peritraumatic ...
https://doi.org/10.1176/ajp.156.11.1808Publication date: 01 November 1999
Pages1811–1813OBJECTIVE: This study approaches the question of nature and nurture of dissociative phenomena. Within Cloninger’s concept of personality, character traits are thought to develop in response to environmental stimuli and conditions during childhood and ...
https://doi.org/10.1176/ajp.156.11.1811Publication date: 01 November 1999
Pages1814–1816OBJECTIVE: Interpersonal psychotherapy is a time-limited treatment initially developed to treat depression. It has not been studied for the treatment of anxiety disorders. METHOD: Interpersonal psychotherapy was modified and tested in a 14-week, open ...
https://doi.org/10.1176/ajp.156.11.1814Publication date: 01 November 1999
Pages1817–1818OBJECTIVE: This study aimed to replicate findings that neurocognitive capacity in schizophrenia is more predictive of acquisition of social skills than are symptoms. METHOD: Thirty-two hospitalized patients with chronic psychotic disorders were randomly ...
https://doi.org/10.1176/ajp.156.11.1817Publication date: 01 November 1999
Pages1819–1821OBJECTIVE: Pharmacologic prescriptions for anxiety disorders have changed significantly in the last decade. This article investigates whether psychosocial treatments, as reported by 362 subjects in the Harvard/Brown Anxiety Disorders Research Program from ...
https://doi.org/10.1176/ajp.156.11.1819Publication date: 01 November 1999
Pages1822–1825OBJECTIVE: d-Serine is a full agonist at the glycine site on the N-methyl-d-aspartate (NMDA) receptor. Previous administration of d-serine to schizophrenic patients taking nonclozapine antipsychotics improved positive, negative, and cognitive symptoms, ...
https://doi.org/10.1176/ajp.156.11.1822Book Forum: CHANGES IN VALUES AND POLICIES
Book Forum: CHILD PSYCHIATRY
Book Forum: TORTURE AND TRAUMA
Book Forum: TREATMENT
Letter to the Editor
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