American Journal of Psychiatry
- Volume 156
- Number 10
- October 1999
Presidential Paper
Editorial
Images In Psychiatry
Special Article
Publication date: 01 October 1999
Pages1500–1505OBJECTIVE: This article highlights the mental health consequences of a domestic terrorist incident involving chemical or biological weapons. METHOD: The author reviews the literature on the neuropsychiatric effects of selected chemical and biological ...
https://doi.org/10.1176/ajp.156.10.1500Publication date: 01 October 1999
Pages1506–1514OBJECTIVE: The authors critically examine the evidence supporting the hypothesis that lithium’s therapeutic effects in bipolar affective disorder are mediated by alterations in the expression of specific genes in critical neuronal circuits. METHOD: Using ...
https://doi.org/10.1176/ajp.156.10.1506Regular Article
Publication date: 01 October 1999
Pages1515–1521OBJECTIVE: The relationships of attention deficit hyperactivity disorder (ADHD), conduct disorder, and gender to substance abuse were studied in a large population-based sample of adolescent twins. METHOD: Structured interviews were administered to 626 ...
https://doi.org/10.1176/ajp.156.10.1515Publication date: 01 October 1999
Pages1522–1528OBJECTIVE: The authors investigated the concurrent and predictive validity of the DSM-III-R diagnosis of personality disorder in adolescents by means of baseline and follow-up assessments of inpatients treated at the Yale Psychiatric Institute. METHOD: ...
https://doi.org/10.1176/ajp.156.10.1522Publication date: 01 October 1999
Pages1529–1535OBJECTIVE: This study examines associations between childhood psychopathology and young adult personality disorder in a random sample of 551 youths, who were 9 to 16 years old at first assessment. METHOD: Subjects were evaluated for DSM-III-R psychiatric ...
https://doi.org/10.1176/ajp.156.10.1529Publication date: 01 October 1999
Pages1536–1544OBJECTIVE: The Challenger space shuttle explosion in January 1986 offered an opportunity to determine what, if any, symptoms of posttraumatic stress disorder (PTSD) and bereavement normal latency-age children and adolescents would develop after a distant, ...
https://doi.org/10.1176/ajp.156.10.1536Publication date: 01 October 1999
Pages1545–1549OBJECTIVE: The aim of this study was to investigate the association of panic attacks and suicide attempts in a community-based sample of 13–14-year-old adolescents. METHOD: The data are from a survey of 1,580 students in an urban public school system ...
https://doi.org/10.1176/ajp.156.10.1545Publication date: 01 October 1999
Pages1550–1556OBJECTIVE: The aim of the study was to investigate affective responses to emotional stimuli in subjects with borderline personality disorder. METHOD: Twenty-four female patients with borderline personality disorder and 27 normal female comparison subjects ...
https://doi.org/10.1176/ajp.156.10.1550Publication date: 01 October 1999
Pages1557–1562OBJECTIVE: This longitudinal follow-up study examined the predictive validity of relatives’ expressed emotion in a group of patients diagnosed with borderline personality disorder. METHOD: Thirty-five patients with DSM-III-R-diagnosed borderline ...
https://doi.org/10.1176/ajp.156.10.1557Publication date: 01 October 1999
Pages1563–1569OBJECTIVE: This study compared the effectiveness of psychoanalytically oriented partial hospitalization with standard psychiatric care for patients with borderline personality disorder. METHOD: Thirty-eight patients with borderline personality disorder, ...
https://doi.org/10.1176/ajp.156.10.1563Publication date: 01 October 1999
Pages1570–1574OBJECTIVE: It has been reported that clinicians are less inclined than researchers to use direct questions in ascertaining the presence of personality disorders, and questions have been raised about the validity of research on personality disorders in ...
https://doi.org/10.1176/ajp.156.10.1570Publication date: 01 October 1999
Pages1575–1579OBJECTIVE: Cytogenetic abnormalities are increased in schizophrenia, suggesting a possible etiologic contribution. However, their clinical and pathophysiologic roles in the disorder are unknown. To investigate this, a group of children and adolescents ...
https://doi.org/10.1176/ajp.156.10.1575Publication date: 01 October 1999
Pages1580–1589OBJECTIVE: Abnormalities in dopamine neurotransmission in the prefrontal cortex have been implicated in the pathophysiology of schizophrenia. However, the integrity of the dopamine projections to the prefrontal cortex in this disorder has not been ...
https://doi.org/10.1176/ajp.156.10.1580Publication date: 01 October 1999
Pages1590–1595OBJECTIVE: Patients with schizophrenia are known to be at high risk for suicide attempts and dying by suicide. However, little research has been conducted to determine whether the risk for suicidal behavior is elevated among patients with psychosis in ...
https://doi.org/10.1176/ajp.156.10.1590Publication date: 01 October 1999
Pages1596–1601OBJECTIVE: The goal of this study was to describe the association between conjugal loss and both syndromal depression and depressive symptoms in a prospective cohort study of people aged 70 years or older. METHOD: A measure of syndromal depression, the ...
https://doi.org/10.1176/ajp.156.10.1596Publication date: 01 October 1999
Pages1602–1607OBJECTIVE: Previous studies reported that depressed subjects had more white matter hyperintensities on magnetic resonance imaging scans than control subjects, but the subjects had cerebrovascular disease risk factors. This study used subjects with a ...
https://doi.org/10.1176/ajp.156.10.1602Publication date: 01 October 1999
Pages1608–1617OBJECTIVE: This study assessed the efficacy of antidepressant treatment (sertraline) and group cognitive behavior therapy, alone or in combination, in primary dysthymia. The clinical features of dysthymia, as well as the functional impairments associated ...
https://doi.org/10.1176/ajp.156.10.1608Publication date: 01 October 1999
Pages1618–1629OBJECTIVE: To assist in the development of a model for the psychopathology of emotions, the present study sought to identify the neural circuits associated with the evaluation of visual stimuli for emotional valence. METHOD: Seventeen healthy individuals ...
https://doi.org/10.1176/ajp.156.10.1618Clinical Case Conference
Brief Report
Publication date: 01 October 1999
Pages1635–1637OBJECTIVE: The mechanism of action of CO2-induced anxiety is unknown and has been little studied. The authors studied healthy volunteers for the possible influence of serotonin (5-HT) on CO2-induced anxiety. METHOD: Fourteen healthy volunteers received ...
https://doi.org/10.1176/ajp.156.10.1635Publication date: 01 October 1999
Pages1638–1640OBJECTIVE: Studies have identified two types of antidepressant response: true drug response and placebo pattern response. This study examined the relationship between true drug response and choline-creatine ratios in the basal ganglia of depressed ...
https://doi.org/10.1176/ajp.156.10.1638Publication date: 01 October 1999
Pages1641–1643OBJECTIVE: The authors investigated the links between depression, cardiac disease, and microcirculatory cerebral blood flow (CBF). METHOD: A magnetic resonance imaging technique based on arterial spin tagging was used to estimate microcirculatory CBF in ...
https://doi.org/10.1176/ajp.156.10.1641Publication date: 01 October 1999
Pages1644–1645OBJECTIVE: The psycho-oncology literature to date contains only one outcome study based on a group model for high-risk relatives of breast cancer patients. The authors set out to study the effects of group intervention in high-risk relatives of breast ...
https://doi.org/10.1176/ajp.156.10.1644Publication date: 01 October 1999
Pages1646–1649OBJECTIVE: This study sought to determine whether thought disorder induced in healthy volunteers by the N-methyl-d-aspartic acid (NMDA) receptor antagonist ketamine resembles the thought disorder found in patients with schizophrenia. METHOD: The Scale for ...
https://doi.org/10.1176/ajp.156.10.1646Publication date: 01 October 1999
Pages1650–1652OBJECTIVE: Increased obstetrical complications have been reported in individuals with adult-onset schizophrenia, with several studies finding an association between such complications and an earlier age at onset. Consequently, obstetrical records were ...
https://doi.org/10.1176/ajp.156.10.1650