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To the Editor: We thank Dr. Goldberg for calling our attention to the findings suggesting that switch risk is increased in patients with bipolar disorder who also have substance use disorders and are treated with antidepressants. Whether the risk we observed is specific to antidepressant-treated patients is an important issue that merits further investigation.

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Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 869
PubMed: 20595436

History

Accepted: April 2010
Published online: 1 July 2010
Published in print: July 2010

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Michael J. Ostacher, M.D., M.P.H.
Roy H. Perlis, M.D., M.Sc.

Competing Interests

The authors disclosures accompany the original article.

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