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Published Online: 18 July 2019

Evidence-Based Principles for Bipolar Disorder Treatment

Publication: FOCUS, A Journal of the American Psychiatric Association
This section contains a compilation of recent publications that have shaped the thinking in the field as well as classic works that remain important to the subject reviewed in this issue. This bibliography has been compiled by experts in the field and members of the editorial and advisory boards. Articles from the bibliography that are reprinted in this issue are in bold type.

2019

Baldessarini RJ, Tondo L, Vázquez GH: Pharmacological treatment of adult bipolar disorder. Mol Psychiatry 2019; 24:198–217
Bousman CA, Arandjelovic K, Mancuso SG, et al: Pharmacogenetic tests and depressive symptom remission: a meta-analysis of randomized controlled trials. Pharmacogenomics 2019; 20:37–47
Vajda FJE, Graham JE, Hitchcock AA, et al: Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register. Seizure 2019; 65:6–11

2018

Butler M, Urosevic S, Desai P, et al: Treatment for Bipolar Disorder in Adults: A Systematic Review. AHRQ Comparative Effectiveness Reviews, Report no 18-EHC012-EF. Rockville, MD, Agency for Healthcare Research and Quality, 2018
Gitlin MJ: Antidepressants in bipolar depression: an enduring controversy. Int J Bipolar Disord 2018; 6:25
Grunze H, Vieta E, Goodwin GM, et al: The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: acute and long-term treatment of mixed states in bipolar disorder. World J Biol Psychiatry 2018; 19:2–58
Harrison PJ, Geddes JR, Tunbridge EM: The emerging neurobiology of bipolar disorder. Trends Neurosci 2018; 41:18–30
Pompili M, Verzura C, Trovini G, et al: Lurasidone: efficacy and safety in the treatment of psychotic and mood disorders. Expert Opin Drug Saf 2018; 17:197–205
Sit DK, McGowan J, Wiltrout C, et al: Adjunctive Bright Light Therapy for Bipolar Depression: A Randomized Double-Blind Placebo-Controlled Trial. Am J Psychiatry 2018; 175:131–139
Stern S, Linker S, Vadodaria KC, et al: Prediction of response to drug therapy in psychiatric disorders. Open Biol 2018; 8:180031

2017

Golden JC, Goethe JW, Woolley SB: Complex psychotropic polypharmacy in bipolar disorder across varying mood polarities: a prospective cohort study of 2712 inpatients. J Affect Disord 2017; 221:6–10
Liu B, Zhang Y, Fang H, et al: Efficacy and safety of long-term antidepressant treatment for bipolar disorders: a meta-analysis of randomized controlled trials. J Affect Disord 2017; 223:41–48
Pickard BS: Genomics of lithium action and response. Neurotherapeutics 2017; 14:582–587
Samara MT, Goldberg Y, Levine SZ, et al: Initial symptom severity of bipolar I disorder and the efficacy of olanzapine: a meta-analysis of individual participant data from five placebo-controlled studies. Lancet Psychiatry 2017; 4:859–867
Smith KA, Cipriani A: Lithium and suicide in mood disorders: updated meta-review of the scientific literature. Bipolar Disord 2017; 19:575–586
Song J, Sjölander A, Joas E, et al: Suicidal behavior during lithium and valproate treatment: a within-individual 8-year prospective study of 50,000 patients with bipolar disorder. Am J Psychiatry 2017; 174:795–802
Young RC, Mulsant BH, Sajatovic M, et al: GERI-BD: A randomized double-blind controlled trial of lithium and divalproex in the treatment of mania in older patients with bipolar disorder. Am J Psychiatry 2017; 174:1086–1093
Zhao H, Nyholt DR: Gene-based analyses reveal novel genetic overlap and allelic heterogeneity across five major psychiatric disorders. Hum Genet 2017; 136:263–274

2015–2016

Alda M: Lithium in the treatment of bipolar disorder: pharmacology and pharmacogenetics. Mol Psychiatry 2015; 20:661–670
Fornaro M, De Berardis D, Koshy AS, et al: Prevalence and clinical features associated with bipolar disorder polypharmacy: a systematic review. Neuropsychiatr Dis Treat 2016; 12:719–735
Geddes JR, Gardiner A, Rendell J, et al: Comparative evaluation of quetiapine plus lamotrigine combination versus quetiapine monotherapy (and folic acid versus placebo) in bipolar depression (CEQUEL): a 2 × 2 factorial randomised trial. Lancet Psychiatry 2016; 3:31–39
Henriksen TE, Skrede S, Fasmer OB, et al: Blue-blocking glasses as additive treatment for mania: a randomized placebo-controlled trial. Bipolar Disord 2016; 18:221–232
Post RM, Leverich GS, Kupka R, et al: Clinical correlates of sustained response to individual drugs used in naturalistic treatment of patients with bipolar disorder. Compr Psychiatry 2016; 66:146–156
Wesseloo R, Kamperman AM, Munk-Olsen T, et al: Risk of postpartum relapse in bipolar disorder and postpartum psychosis: a systematic review and meta-analysis. Am J Psychiatry 2016; 173:117–127
Yatham LN, Beaulieu S, Schaffer A, et al: Optimal duration of risperidone or olanzapine adjunctive therapy to mood stabilizer following remission of a manic episode: a CANMAT randomized double-blind trial. Mol Psychiatry 2016; 21:1050–1056

Further Reading

Adli M, Whybrow PC, Grof P, et al: Use of polypharmacy and self-reported mood in outpatients with bipolar disorder. Int J Psychiatry Clin Pract 2005; 9:251–256
Alsdorf R, Wyszynski DF: Teratogenicity of sodium valproate. Expert Opin Drug Saf 2005; 4:345–353
Altshuler LL, Post RM, Hellemann G, et al: Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study. J Clin Psychiatry 2009; 70:450–457
Altshuler LL, Suppes T, Black DO, et al: Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants. Am J Psychiatry 2006; 163:313–315
Bergink V, Bouvy PF, Vervoort JSP, et al: Prevention of postpartum psychosis and mania in women at high risk. Am J Psychiatry 2012; 169:609–615
Calabrese JR, Shelton MD, Rapport DJ, et al: A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorder. Am J Psychiatry 2005; 162:2152–2161
Deligiannidis KM, Byatt N, Freeman MP: Pharmacotherapy for mood disorders in pregnancy: a review of pharmacokinetic changes and clinical recommendations for therapeutic drug monitoring. J Clin Psychopharmacol 2014; 34:244–255
Diav-Citrin O, Shechtman S, Tahover E, et al: Pregnancy outcome following in utero exposure to lithium: a prospective, comparative, observational study. Am J Psychiatry 2014; 171:785–794
Geddes JR, Goodwin GM, Rendell J, et al: Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. Lancet 2010; 375:385–395
Ghaemi SN, Ostacher MM, El-Mallakh RS, et al: Antidepressant discontinuation in bipolar depression: a Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) randomized clinical trial of long-term effectiveness and safety. J Clin Psychiatry 2010; 71:372–380
Goldberg JF, Brooks JO III, Kurita K, et al: Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP-BD. J Clin Psychiatry 2009; 70:155–162
Goldberg JF, Burdick KE, Endick CJ: Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression. Am J Psychiatry 2004; 161:564–566
Jentink J, Loane MA, Dolk H, et al: Valproic acid monotherapy in pregnancy and major congenital malformations. N Engl J Med 2010; 362:2185–2193
Kessing LV, Hellmund G, Andersen PK: Predictors of excellent response to lithium: results from a nationwide register-based study. Int Clin Psychopharmacol 2011; 26:323–328
Lam DH, Hayward P, Watkins ER, et al: Relapse prevention in patients with bipolar disorder: cognitive therapy outcome after 2 years. Am J Psychiatry 2005; 162:324–329
Miklowitz DJ, George EL, Richards JA, et al: A randomized study of family-focused psychoeducation and pharmacotherapy in the outpatient management of bipolar disorder. Arch Gen Psychiatry 2003; 60:904–912
Miklowitz DJ, Otto MW, Frank E, et al: Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program. Arch Gen Psychiatry 2007; 64:419–426
Munk-Olsen T, Laursen TM, Mendelson T, et al: Risks and predictors of readmission for a mental disorder during the postpartum period. Arch Gen Psychiatry 2009; 66:189–195
Newport DJ, Viguera AC, Beach AJ, et al: Lithium placental passage and obstetrical outcome: implications for clinical management during late pregnancy. Am J Psychiatry 2005; 162:2162–2170
Nierenberg AA, Friedman ES, Bowden CL, et al: Lithium treatment moderate-dose use study (LiTMUS) for bipolar disorder: a randomized comparative effectiveness trial of optimized personalized treatment with and without lithium. Am J Psychiatry 2013; 170:102–110
Pacchiarotti I, Bond DJ, Baldessarini RJ, et al: The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry 2013; 170:1249–1262
Popovic D, Reinares M, Goikolea JM, et al: Polarity index of pharmacological agents used for maintenance treatment of bipolar disorder. Eur Neuropsychopharmacol 2012; 22:339–346
Reinares M, Rosa AR, Franco C, et al: A systematic review on the role of anticonvulsants in the treatment of acute bipolar depression. Int J Neuropsychopharmacol 2013; 16:485–496
Rosa AR, Fountoulakis K, Siamouli M, et al: Is anticonvulsant treatment of mania a class effect? Data from randomized clinical trials. CNS Neurosci Ther 2011; 17:167–177
Sachs GS, Nierenberg AA, Calabrese JR, et al: Effectiveness of adjunctive antidepressant treatment for bipolar depression. N Engl J Med 2007; 356:1711–1722
Sidor MM, Macqueen GM: Antidepressants for the acute treatment of bipolar depression: a systematic review and meta-analysis. J Clin Psychiatry 2011; 72:156–167
Swann AC, Bowden CL, Morris D, et al: Depression during mania: treatment response to lithium or divalproex. Arch Gen Psychiatry 1997; 54:37–42
Taylor DM, Cornelius V, Smith L, et al: Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis. Acta Psychiatr Scand 2014; 130:452–469
Tohen M, Vieta E, Calabrese J, et al: Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Arch Gen Psychiatry 2003; 60:1079–1088
Viguera AC, Whitfield T, Baldessarini RJ, et al: Risk of recurrence in women with bipolar disorder during pregnancy: prospective study of mood stabilizer discontinuation. Am J Psychiatry 2007; 164:1817–1824, quiz 1923
Yonkers KA, Wisner KL, Stowe Z, et al: Management of bipolar disorder during pregnancy and the postpartum period. Am J Psychiatry 2004; 161:608–620

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FOCUS, A Journal of the American Psychiatric Association
Pages: 272 - 274

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Published in print: Summer 2019
Published online: 18 July 2019

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