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Published Online: August 1969

A Theory of Neuronal Malfunction in Schizophrenia

Publication: American Journal of Psychiatry

Abstract

A considerable amount of biological research into schizophrenia, mainly upon blood fluids, is performed throughout the world. The authors report their latest findings on a plasma protein factor and relate these findings to other domestic research and to recent research in other nations, particularly the Soviet Union. They hypothesize that a malcontrolled blood protein contributes to the genesis of schizophrenia by selectively altering neuronal permeability to precursors of important neurotransmitters; if this occurs, it would disrupt information processing in the brain.

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Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 149 - 156
PubMed: 4185016

History

Published in print: August 1969
Published online: 1 April 2006

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Director, Lafayette Clinic, 951 E. Lafayette, Detroit, Mich. 48207, professor and chairman, department of psychiatry, Wayne State University
Associate director, head, biochemistry laboratories, Lafayette Clinic, 951 E. Lafayette, Detroit, Mich. 48207, assistant professor, department of biochemistry, Wayne State University
Lafayette Clinic, 951 E. Lafayette, Detroit, Mich. 48207, professor, department of psychiatry, Wayne State University

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