American Journal of Psychiatry
- Volume 154
- Number 4
- April 1997
Publication date: 01 April 1997
Pages448–456OBJECTIVE: This article explores the clinical, legal, and ethical problems that typically occur when a psychotherapist serves as both a treating clinician and forensic evaluator (or expert witness) in the same case. METHOD: The professional literature, ...
https://doi.org/10.1176/ajp.154.4.448Publication date: 01 April 1997
Pages457–465OBJECTIVE: This international, multicenter double-blind trial was designed to compare the therapeutic profile of an atypical antipsychotic, olanzapine, with that of a conventional dopamine D2 antagonist, haloperidol. METHOD: A total of 1,996 patients at ...
https://doi.org/10.1176/ajp.154.4.457Publication date: 01 April 1997
Pages466–474OBJECTIVE: The authors investigated whether primary negative symptoms of schizophrenia are enduring or treatment-responsive. METHODS: Previously, a double-blind, random-assignment trial of the novel antipsychotic olanzapine (in low, medium, and high dose ...
https://doi.org/10.1176/ajp.154.4.466Publication date: 01 April 1997
Pages475–482OBJECTIVE: The age at onset of schizophrenia for males has usually but not always been reported to be less than that for females. Early onset has also been associated with poor response to neuroleptic treatment and worse long-term outcome. The authors ...
https://doi.org/10.1176/ajp.154.4.475Publication date: 01 April 1997
Pages483–489OBJECTIVE: The authors examined the refusal of antipsychotic medications and associated outcomes prospectively in a group of 348 psychiatric patients admitted to three acute inpatient units in a state- operated mental health facility in Virginia where ...
https://doi.org/10.1176/ajp.154.4.483Publication date: 01 April 1997
Pages490–496OBJECTIVE: This study was undertaken to measure serotonergic modulation of dopamine in vivo by using positron emission tomography (PET), a radiotracer for the striatal dopamine D2 receptor ([11C]raclopride), and a pharmacologic challenge of the serotonin ...
https://doi.org/10.1176/ajp.154.4.490Publication date: 01 April 1997
Pages497–501OBJECTIVE: The authors' goal was to characterize the clinical and demographic features of vascular depression. METHOD: They classified 89 depressed patients into two groups-those with vascular (N = 32) and nonvascular (N = 57) depression-on the basis of ...
https://doi.org/10.1176/ajp.154.4.497Publication date: 01 April 1997
Pages502–509OBJECTIVE: The authors tested the hypothesis that patients whose episodes of major depression evidenced more neurobiological disturbance would be less responsive to psychotherapy. METHOD: The study subjects were outpatients who were given a diagnosis of ...
https://doi.org/10.1176/ajp.154.4.502Publication date: 01 April 1997
Pages510–515OBJECTIVE: The purpose of this study was to compare the sustained effects of two cognitive, psychoeducational preventive interventions for families in which a parent had an affective disorder. METHOD: Thirty-seven families, in which there was a child ...
https://doi.org/10.1176/ajp.154.4.510Publication date: 01 April 1997
Pages516–522OBJECTIVE: The purpose of this study was to investigate the pharmacokinetics of fluvoxamine in the human brain by using fluorine-19 magnetic resonance spectroscopy (19F MRS) and to assess the relationships among fluvoxamine brain levels, fluvoxamine ...
https://doi.org/10.1176/ajp.154.4.516Publication date: 01 April 1997
Pages523–531OBJECTIVE: Two treatments for bulimia nervosa have emerged as having established efficacy: cognitive-behavioral therapy and antidepressant medication. This study sought to address 1) how the efficacy of a psychodynamically oriented supportive ...
https://doi.org/10.1176/ajp.154.4.523Publication date: 01 April 1997
Pages532–535OBJECTIVE: The present study examined probandwise concordance rates for attention deficit hyperactivity disorder (ADHD) in a community sample of 194 monozygotic and 94 dizygotic male twins, ages 11-12 years. METHOD: DSM-III and DSM-III-R diagnoses of ADHD ...
https://doi.org/10.1176/ajp.154.4.532Publication date: 01 April 1997
Pages536–542OBJECTIVE: The authors evaluated the effectiveness of brief trauma/grief-focused psychotherapy among early adolescents exposed to the 1988 earthquake in Armenia. METHOD: Posttraumatic stress and depressive reactions among treated and not treated subjects ...
https://doi.org/10.1176/ajp.154.4.536Publication date: 01 April 1997
Pages548–550OBJECTIVE: This study tested the hypothesis that resumption of lithium treatment of bipolar disorders may be less effective after maintenance treatment has been discontinued. METHOD: Eighty-six patients with type I or II bipolar disorder, not selected ...
https://doi.org/10.1176/ajp.154.4.548Publication date: 01 April 1997
Pages551–553OBJECTIVE: The aim of this study was to verify reduction of early affective morbidity by gradual, rather than rapid, discontinuation of lithium treatment. METHOD: For 78 patients with bipolar disorders, lithium treatment was discontinued either rapidly (...
https://doi.org/10.1176/ajp.154.4.551Publication date: 01 April 1997
Pages554–555OBJECTIVE: The authors examined the efficacy of lithium carbonate for treating conduct disorder in adolescents. METHOD: The subjects were 33 inpatients aged 12-17 years. Lithium or placebo was administered in a double-blind fashion for 2 weeks. RESULTS: ...
https://doi.org/10.1176/ajp.154.4.554Publication date: 01 April 1997
Pages556–558OBJECTIVE: Indirect evidence suggests that abnormalities in serotonergic function may be involved in the pathogenesis of premenstrual dysphoric disorder. The goal of this study was to test the hypothesis of serotonergic deficiency in premenstrual ...
https://doi.org/10.1176/ajp.154.4.556Publication date: 01 April 1997
Pages559–561OBJECTIVE: The adequacy of pharmacologic treatment received by patients with psychotic major depression was evaluated. METHOD: The authors systematically assessed the pharmacotherapy received by 187 depressed patients before initiation of ECT and compared ...
https://doi.org/10.1176/ajp.154.4.559Publication date: 01 April 1997
Pages562–565OBJECTIVE: The authors' goal was to examine the clinical presentation of a group of depressed elderly patients with clinically defined risk factors for vascular depression compared with a group of elderly depressed patients without such risk factors. ...
https://doi.org/10.1176/ajp.154.4.562Publication date: 01 April 1997
Pages566–569OBJECTIVE: The authors investigated the hypothesis that in acute anorexia nervosa a low body weight predicts a poor weight prognosis for the future. METHOD: The body mass indexes at referral of 272 female patients were examined in relation to the body ...
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