American Journal of Psychiatry
- Volume 154
- Number 5
- May 1997
Publication date: 01 May 1997
Pages595–602OBJECTIVE: Pharmacological treatments for certain psychiatric disorders in young people are often ineffective and may cause major side effects; thus, it is important to investigate other treatments. This article reviews the literature on the efficacy and ...
https://doi.org/10.1176/ajp.154.5.595Publication date: 01 May 1997
Pages603–608OBJECTIVE: The relationship between number of apolipoprotein E epsilon 4 (APOE epsilon 4) alleles and the rate of cognitive decline in patients with Alzheimer's disease was examined. METHOD: Rate of decline in score on the Mini-Mental State was measured ...
https://doi.org/10.1176/ajp.154.5.603Publication date: 01 May 1997
Pages609–615OBJECTIVE: The validity of subjective memory complaints has been questioned by clinical studies that have shown little relationship between memory complaints and objective memory performance. These studies often have been cross-sectional in design, have ...
https://doi.org/10.1176/ajp.154.5.609Publication date: 01 May 1997
Pages616–623OBJECTIVE: The aim of this study was to confirm and extend the authors' previous work indicating that symptoms of traumatic grief are predictors of future physical and mental health outcomes. METHOD: The study group consisted of 150 future widows and ...
https://doi.org/10.1176/ajp.154.5.616Publication date: 01 May 1997
Pages624–629OBJECTIVE: Corticotropin-releasing factor (CRF) and somatostatin both play important roles in mediating responses to acute and chronic stress. The purpose of this study was to measure CSF concentrations of CRF and somatostatin in patients with chronic ...
https://doi.org/10.1176/ajp.154.5.624Publication date: 01 May 1997
Pages630–634OBJECTIVE: Although there is evidence that stress is associated with alterations in immunity, the role of emotional factors in the onset and course of immune-based diseases such as cancer and AIDS has not been established. This prospective study was ...
https://doi.org/10.1176/ajp.154.5.630Publication date: 01 May 1997
Pages635–639OBJECTIVE: The authors' goal was to investigate the issue of intellectual deterioration in schizophrenia. METHOD: They examined the childhood IQs of adult patients with schizophrenia who had attended a child psychiatry service where measurement of ...
https://doi.org/10.1176/ajp.154.5.635Publication date: 01 May 1997
Pages640–646OBJECTIVE: Schizophrenia has long been thought to be characterized by a fundamental disturbance in semantic associations, which has often been presumed to be of neurobiological origin. The authors examined the neurophysiological characteristics of ...
https://doi.org/10.1176/ajp.154.5.640Publication date: 01 May 1997
Pages647–654OBJECTIVE: Previous studies of covert visuospatial attention in schizophrenia suggest a subtle form of right hemispatial neglect in acutely ill patients but not in chronic, stable patients. Because of previous work documenting various visual information-...
https://doi.org/10.1176/ajp.154.5.647Publication date: 01 May 1997
Pages655–660OBJECTIVE: Previous research has shown biological, phenomenological, and cognitive similarities between schizophrenic patients and individuals with schizophrenia-related personality disorders and features. Evidence further suggests that of these common ...
https://doi.org/10.1176/ajp.154.5.655Publication date: 01 May 1997
Pages661–667OBJECTIVE: The planum temporale, the posterior superior surface of the superior temporal gyrus, is a highly lateralized brain structure involved with language. In schizophrenic patients the authors previously found consistent reversal of the normal left-...
https://doi.org/10.1176/ajp.154.5.661Publication date: 01 May 1997
Pages668–673OBJECTIVE: Major depressive disorder in adolescents is characterized as treatment resistant, but a previous open-label trial of pulse intravenous clomipramine demonstrated rapid relief of depressive symptoms. In the present study a single intravenous dose ...
https://doi.org/10.1176/ajp.154.5.668Publication date: 01 May 1997
Pages674–676OBJECTIVE: This study compared the performance of four brief screening measures for depression in a group of terminally ill patients. The methods included 1) a single-item interview assessing depressed mood, 2) a two-item interview assessing depressed ...
https://doi.org/10.1176/ajp.154.5.674Publication date: 01 May 1997
Pages682–684OBJECTIVE: This study examined glucose metabolism in the anterior and posterior cingulate cortex in schizophrenia. METHOD: Fifty unmedicated male schizophrenic patients and 24 normal men were studied with positron emission tomography. RESULTS: Compared ...
https://doi.org/10.1176/ajp.154.5.682Publication date: 01 May 1997
Pages685–687OBJECTIVE: Anomalous planum temporale asymmetry has been linked to both schizophrenia and dyslexia. The authors examined the planum temporale of adolescents with childhood-onset schizophrenia who had a high rate of prepsychotic language disorders. METHOD: ...
https://doi.org/10.1176/ajp.154.5.685Publication date: 01 May 1997
Pages688–690OBJECTIVE: The authors measured N-acetylaspartate (a putative neuronal marker), using in vivo proton magnetic resonance spectroscopic imaging (1H-MRSI), in the frontal lobes of schizophrenic patients and normal subjects. METHOD: Frontal lobe 1H-MRSI was ...
https://doi.org/10.1176/ajp.154.5.688Publication date: 01 May 1997
Pages691–693OBJECTIVE: The authors evaluated the presence or absence of informative morphogenetic variants in patients with schizophrenia compared with alcohol-dependent patients. METHODS: Taking into consideration the criticisms of the Waldrop Scale, which was ...
https://doi.org/10.1176/ajp.154.5.691Publication date: 01 May 1997
Pages694–696OBJECTIVE: This study was designed to investigate in cognitively normal subjects the possible association between hypersensitive pupil dilation response to the cholinergic antagonist tropicamide and the presence of the apolipoprotein E epsilon 4 (APOE4) ...
https://doi.org/10.1176/ajp.154.5.694Publication date: 01 May 1997
Pages697–699OBJECTIVE: Personality traits in human subjects have shown considerable heritable components. Recently, two research groups reported associations between dopamine D4 receptor genotypes and the personality trait known as novelty seeking. This study was an ...
https://doi.org/10.1176/ajp.154.5.697Publication date: 01 May 1997
Pages700–702OBJECTIVE: The anxiogenic and panicogenic effects of peripheral administration of the cholecystokinin-B receptor agonist pentagastrin and placebo were evaluated in patients with generalized anxiety disorder and normal comparison subjects. METHODS: Seven ...
https://doi.org/10.1176/ajp.154.5.700Past Issues
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