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American Journal of Psychiatry

  • Volume 154
  • Number 8
  • August 1997

Publication date: 01 August 1997

Pages1047–1050

OBJECTIVE: This study reports the first paired measurements of glucose metabolism and volume of the anterior cingulate gyrus in autism. METHOD: Magnetic resonance imaging (MRI) and positron emission tomography (PET) scans of seven high-functioning ...

https://doi.org/10.1176/ajp.154.8.1047

Publication date: 01 August 1997

Pages1051–1056

OBJECTIVE: The purpose of this study was to examine the size of subregions of the corpus callosum in autistic individuals. METHOD: The areas of three subregions (anterior, body, and posterior) of the corpus callosum were examined on midsagittal magnetic ...

https://doi.org/10.1176/ajp.154.8.1051

Publication date: 01 August 1997

Pages1057–1062

OBJECTIVE: The authors evaluated the relative efficacy and safety of pimozide and haloperidol in the treatment of Gilles de la Tourette's syndrome in children and adolescents. METHOD: A double-blind, 24-week, placebo-controlled double crossover study of ...

https://doi.org/10.1176/ajp.154.8.1057

Publication date: 01 August 1997

Pages1063–1069

OBJECTIVE: Down's syndrome is characterized by the genetically programmed accumulation of substantial Alzheimer's disease neuropathology after age 40 and the development of early dementia years later, providing a unique human model to investigate the ...

https://doi.org/10.1176/ajp.154.8.1063

Publication date: 01 August 1997

Pages1070–1075

OBJECTIVE: Experience with a new surrogate consent system for patients with Alzheimer's disease is reviewed. It was hypothesized that as patients' cognitive status deteriorated, surrogate consent through a durable power of attorney would become necessary ...

https://doi.org/10.1176/ajp.154.8.1070

Publication date: 01 August 1997

Pages1076–1080

OBJECTIVE: This investigation was designed to assess the acoustic startle response in treatment-seeking women with sexual assault-related posttraumatic stress disorder (PTSD). METHOD: Thirteen patients with sexual assault-related PTSD and 16 healthy ...

https://doi.org/10.1176/ajp.154.8.1076

Publication date: 01 August 1997

Pages1081–1088

OBJECTIVE: The aims of this study were to investigate psychophysiological changes associated with peritraumatic dissociation in female victims of recent rape and to assess the relation between these changes and symptoms of posttraumatic stress disorder (...

https://doi.org/10.1176/ajp.154.8.1081

Publication date: 01 August 1997

Pages1089–1095

OBJECTIVE: This study tested the hypothesis that compared to other DSM- IV specific phobia types, situational specific phobias have more in common with panic disorder and agoraphobia. METHOD: Responses to hyperventilation and CO2 inhalation were compared ...

https://doi.org/10.1176/ajp.154.8.1089

Publication date: 01 August 1997

Pages1096–1100

OBJECTIVE: gamma-Aminobutyric acid type A (GABAA) receptor subunit genes are candidate genes for panic disorder. Benzodiazepine agonists acting at this receptor can suppress panic attacks, and both inverse agonists and antagonists can precipitate them. ...

https://doi.org/10.1176/ajp.154.8.1096

Publication date: 01 August 1997

Pages1101–1106

OBJECTIVE: The purpose of this study was to assess a full range of pathological childhood experiences reported by patients with criteria- defined borderline personality disorder and comparison patients with other personality disorders. METHOD: The ...

https://doi.org/10.1176/ajp.154.8.1101

Publication date: 01 August 1997

Pages1107–1113

OBJECTIVE: In contrast to the recent surge of interest in other dissociative disorders, DSM-III-R depersonalization disorder has not been thoroughly investigated and characterized. The authors systematically elucidated its phenomenology, comorbidity, ...

https://doi.org/10.1176/ajp.154.8.1107

Publication date: 01 August 1997

Pages1114–1119

OBJECTIVE: Full and partial posttraumatic stress disorder (PTSD) following trauma exposure were examined in a community sample in order to determine their prevalence and their relative importance and functional significance. METHOD: A standardized ...

https://doi.org/10.1176/ajp.154.8.1114

Publication date: 01 August 1997

Pages1120–1126

OBJECTIVE: To examine the prevalence of obsessive-compulsive symptoms and DSM-IV obsessive-compulsive disorder (OCD), the authors conducted a telephone survey of 2,261 adults in four regions of Canada. METHOD: Trained lay interviewers administered a ...

https://doi.org/10.1176/ajp.154.8.1120

Publication date: 01 August 1997

Pages1127–1132

OBJECTIVE: The goal of this study was to better understand the etiology, clinical characteristics, and prognosis of eating disorders in males. METHOD: All males with eating disorders who had been treated at Massachusetts General Hospital from Jan. 1, 1980,...

https://doi.org/10.1176/ajp.154.8.1127

Publication date: 01 August 1997

Pages1133–1138

OBJECTIVE: The authors examined the temporal stability and predictive utility of bulimic symptoms and related variables over the course of 10 years, from 1982 to 1992. METHOD: The subjects were 459 women who were aged 18-22 years in 1982 and were surveyed ...

https://doi.org/10.1176/ajp.154.8.1133

Publication date: 01 August 1997

Pages1146–1147

OBJECTIVE: The purpose of this study was to identify the specific expanded CAG/CTG trinucleotide repeat associated with bipolar disorder. METHOD: The study employed an efficient multistage approach for using a genomic CAG/CTG screening set. RESULTS: The ...

https://doi.org/10.1176/ajp.154.8.1146

Publication date: 01 August 1997

Pages1148–1150

OBJECTIVE: This study aimed to evaluate aspects of second messenger function in the brain of suicide victims and patients with bipolar disorder. METHOD: Inositol and its synthetic enzyme, inositol monophosphatase, were measured in postmortem brain samples ...

https://doi.org/10.1176/ajp.154.8.1148

Publication date: 01 August 1997

Pages1151–1152

OBJECTIVE: Although the antidepressant mechanism of ECT is unknown, there are considerable data to support serotonergic involvement. The effects of tryptophan depletion were studied in patients with major depression treated successfully with ECT. METHOD: ...

https://doi.org/10.1176/ajp.154.8.1151

Publication date: 01 August 1997

Pages1153–1155

OBJECTIVE: Brain serotonin systems might be involved in the pathophysiology of seasonal affective disorder. The authors tested whether tryptophan depletion alters the mood of depressed patients with seasonal affective disorder. METHOD: Eleven drug-free ...

https://doi.org/10.1176/ajp.154.8.1153

Publication date: 01 August 1997

Pages1156–1158

OBJECTIVE: The authors performed a case-control study of neuroleptic malignant syndrome to identify potential risk factors. METHOD: Twenty- five patients with neuroleptic malignant syndrome were matched with 50 comparison subjects on age, sex, primary ...

https://doi.org/10.1176/ajp.154.8.1156

Publication date: 01 August 1997

Pages1159–1160

OBJECTIVE: The authors investigated the extent and characteristics of published psychiatric research from U.S. and Canadian medical schools that was carried out without external funding. METHOD: They reviewed reports of unfunded research in 14 psychiatric ...

https://doi.org/10.1176/ajp.154.8.1159

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