American Journal of Psychiatry
- Volume 154
- Number 8
- August 1997
Publication date: 01 August 1997
Pages1047–1050OBJECTIVE: This study reports the first paired measurements of glucose metabolism and volume of the anterior cingulate gyrus in autism. METHOD: Magnetic resonance imaging (MRI) and positron emission tomography (PET) scans of seven high-functioning ...
https://doi.org/10.1176/ajp.154.8.1047Publication date: 01 August 1997
Pages1051–1056OBJECTIVE: The purpose of this study was to examine the size of subregions of the corpus callosum in autistic individuals. METHOD: The areas of three subregions (anterior, body, and posterior) of the corpus callosum were examined on midsagittal magnetic ...
https://doi.org/10.1176/ajp.154.8.1051Publication date: 01 August 1997
Pages1057–1062OBJECTIVE: The authors evaluated the relative efficacy and safety of pimozide and haloperidol in the treatment of Gilles de la Tourette's syndrome in children and adolescents. METHOD: A double-blind, 24-week, placebo-controlled double crossover study of ...
https://doi.org/10.1176/ajp.154.8.1057Publication date: 01 August 1997
Pages1063–1069OBJECTIVE: Down's syndrome is characterized by the genetically programmed accumulation of substantial Alzheimer's disease neuropathology after age 40 and the development of early dementia years later, providing a unique human model to investigate the ...
https://doi.org/10.1176/ajp.154.8.1063Publication date: 01 August 1997
Pages1070–1075OBJECTIVE: Experience with a new surrogate consent system for patients with Alzheimer's disease is reviewed. It was hypothesized that as patients' cognitive status deteriorated, surrogate consent through a durable power of attorney would become necessary ...
https://doi.org/10.1176/ajp.154.8.1070Publication date: 01 August 1997
Pages1076–1080OBJECTIVE: This investigation was designed to assess the acoustic startle response in treatment-seeking women with sexual assault-related posttraumatic stress disorder (PTSD). METHOD: Thirteen patients with sexual assault-related PTSD and 16 healthy ...
https://doi.org/10.1176/ajp.154.8.1076Publication date: 01 August 1997
Pages1081–1088OBJECTIVE: The aims of this study were to investigate psychophysiological changes associated with peritraumatic dissociation in female victims of recent rape and to assess the relation between these changes and symptoms of posttraumatic stress disorder (...
https://doi.org/10.1176/ajp.154.8.1081Publication date: 01 August 1997
Pages1089–1095OBJECTIVE: This study tested the hypothesis that compared to other DSM- IV specific phobia types, situational specific phobias have more in common with panic disorder and agoraphobia. METHOD: Responses to hyperventilation and CO2 inhalation were compared ...
https://doi.org/10.1176/ajp.154.8.1089Publication date: 01 August 1997
Pages1096–1100OBJECTIVE: gamma-Aminobutyric acid type A (GABAA) receptor subunit genes are candidate genes for panic disorder. Benzodiazepine agonists acting at this receptor can suppress panic attacks, and both inverse agonists and antagonists can precipitate them. ...
https://doi.org/10.1176/ajp.154.8.1096Publication date: 01 August 1997
Pages1101–1106OBJECTIVE: The purpose of this study was to assess a full range of pathological childhood experiences reported by patients with criteria- defined borderline personality disorder and comparison patients with other personality disorders. METHOD: The ...
https://doi.org/10.1176/ajp.154.8.1101Publication date: 01 August 1997
Pages1107–1113OBJECTIVE: In contrast to the recent surge of interest in other dissociative disorders, DSM-III-R depersonalization disorder has not been thoroughly investigated and characterized. The authors systematically elucidated its phenomenology, comorbidity, ...
https://doi.org/10.1176/ajp.154.8.1107Publication date: 01 August 1997
Pages1114–1119OBJECTIVE: Full and partial posttraumatic stress disorder (PTSD) following trauma exposure were examined in a community sample in order to determine their prevalence and their relative importance and functional significance. METHOD: A standardized ...
https://doi.org/10.1176/ajp.154.8.1114Publication date: 01 August 1997
Pages1120–1126OBJECTIVE: To examine the prevalence of obsessive-compulsive symptoms and DSM-IV obsessive-compulsive disorder (OCD), the authors conducted a telephone survey of 2,261 adults in four regions of Canada. METHOD: Trained lay interviewers administered a ...
https://doi.org/10.1176/ajp.154.8.1120Publication date: 01 August 1997
Pages1127–1132OBJECTIVE: The goal of this study was to better understand the etiology, clinical characteristics, and prognosis of eating disorders in males. METHOD: All males with eating disorders who had been treated at Massachusetts General Hospital from Jan. 1, 1980,...
https://doi.org/10.1176/ajp.154.8.1127Publication date: 01 August 1997
Pages1133–1138OBJECTIVE: The authors examined the temporal stability and predictive utility of bulimic symptoms and related variables over the course of 10 years, from 1982 to 1992. METHOD: The subjects were 459 women who were aged 18-22 years in 1982 and were surveyed ...
https://doi.org/10.1176/ajp.154.8.1133Publication date: 01 August 1997
Pages1146–1147OBJECTIVE: The purpose of this study was to identify the specific expanded CAG/CTG trinucleotide repeat associated with bipolar disorder. METHOD: The study employed an efficient multistage approach for using a genomic CAG/CTG screening set. RESULTS: The ...
https://doi.org/10.1176/ajp.154.8.1146Publication date: 01 August 1997
Pages1148–1150OBJECTIVE: This study aimed to evaluate aspects of second messenger function in the brain of suicide victims and patients with bipolar disorder. METHOD: Inositol and its synthetic enzyme, inositol monophosphatase, were measured in postmortem brain samples ...
https://doi.org/10.1176/ajp.154.8.1148Publication date: 01 August 1997
Pages1151–1152OBJECTIVE: Although the antidepressant mechanism of ECT is unknown, there are considerable data to support serotonergic involvement. The effects of tryptophan depletion were studied in patients with major depression treated successfully with ECT. METHOD: ...
https://doi.org/10.1176/ajp.154.8.1151Publication date: 01 August 1997
Pages1153–1155OBJECTIVE: Brain serotonin systems might be involved in the pathophysiology of seasonal affective disorder. The authors tested whether tryptophan depletion alters the mood of depressed patients with seasonal affective disorder. METHOD: Eleven drug-free ...
https://doi.org/10.1176/ajp.154.8.1153Publication date: 01 August 1997
Pages1156–1158OBJECTIVE: The authors performed a case-control study of neuroleptic malignant syndrome to identify potential risk factors. METHOD: Twenty- five patients with neuroleptic malignant syndrome were matched with 50 comparison subjects on age, sex, primary ...
https://doi.org/10.1176/ajp.154.8.1156Publication date: 01 August 1997
Pages1159–1160OBJECTIVE: The authors investigated the extent and characteristics of published psychiatric research from U.S. and Canadian medical schools that was carried out without external funding. METHOD: They reviewed reports of unfunded research in 14 psychiatric ...
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