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American Journal of Psychiatry

  • Volume 154
  • Number 9
  • September 1997

Publication date: 01 September 1997

Pages1199–1208

OBJECTIVE: The authors describe the APA Practice Research Network (PRN), a national research initiative that ultimately will engage 1,000 practicing psychiatrists in collaborative clinical and services research. The PRN is designed to generate practice-...

https://doi.org/10.1176/ajp.154.9.1199

Publication date: 01 September 1997

Pages1209–1213

OBJECTIVE: Animal data suggest that the strong euphoriant effects of cocaine are related to the drug's enhancement of available dopamine at the synaptic cleft. The authors' goal was to determine whether this mechanism is the same in humans because the ...

https://doi.org/10.1176/ajp.154.9.1209

Publication date: 01 September 1997

Pages1214–1219

OBJECTIVE: Previous research has suggested that support services supplementing methadone maintenance programs vary in their cost- effectiveness. This study examined the cost-effectiveness of varying levels of supplementary support services to determine ...

https://doi.org/10.1176/ajp.154.9.1214

Publication date: 01 September 1997

Pages1220–1227

OBJECTIVE: An excess of obstetric complications in the histories of schizophrenic patients is a well-replicated finding, but less consistent results have been found concerning the relationships between obstetric complications and family history of ...

https://doi.org/10.1176/ajp.154.9.1220

Publication date: 01 September 1997

Pages1228–1234

OBJECTIVE: This study compared insured and uninsured schizophrenic inpatients in China and examined changes in the acute inpatient care of schizophrenic patients during China's economic reform era. METHOD: Detailed chart reviews of 50 randomly selected ...

https://doi.org/10.1176/ajp.154.9.1228

Publication date: 01 September 1997

Pages1235–1242

OBJECTIVE: The authors examined the clinical characteristics of suicide victims with schizophrenia in the general population of Finland. METHOD: As part of the nationwide National Suicide Prevention Project in Finland, all suicides over a 12-month period ...

https://doi.org/10.1176/ajp.154.9.1235

Publication date: 01 September 1997

Pages1243–1247

OBJECTIVE: The authors sought to determine the time to clozapine response in treatment-refractory patients with schizophrenia. METHOD: Antipsychotic response to a clozapine trial was examined in 50 treatment-refractory schizophrenic inpatients. Subjects ...

https://doi.org/10.1176/ajp.154.9.1243

Publication date: 01 September 1997

Pages1248–1254

OBJECTIVE: Tardive dyskinesia is a serious and common complication of neuroleptic treatment. Olanzapine is a novel antipsychotic agent exhibiting regional mesolimbic dopaminergic selectivity and a broad- based pharmacology encompassing serotonin, dopamine,...

https://doi.org/10.1176/ajp.154.9.1248

Publication date: 01 September 1997

Pages1255–1260

OBJECTIVE: The purpose of this study was to determine the concentrations of sertraline and desmethylsertraline in both human breast milk and infant serum. METHOD: Breast milk samples from 12 women were collected at specific time intervals after oral doses ...

https://doi.org/10.1176/ajp.154.9.1255

Publication date: 01 September 1997

Pages1261–1264

OBJECTIVE: It is now well documented that fluoxetine is a viable treatment option for patients with obsessive-compulsive disorder (OCD), and there is a small body of evidence indicating that monoamine oxidase inhibitors may be effective in at least a ...

https://doi.org/10.1176/ajp.154.9.1261

Publication date: 01 September 1997

Pages1265–1271

OBJECTIVE: The authors previously reported that birth complications interact with early maternal rejection in predisposing individuals to violence at age 18 years. This study extended the follow-up period for violent offending from 18 years to 34 years, ...

https://doi.org/10.1176/ajp.154.9.1265

Publication date: 01 September 1997

Pages1272–1276

OBJECTIVE: Evaluation of patients' potential for violence is an important component of care in psychiatric emergency and inpatient settings. Although situational variables are widely acknowledged to influence the risk of violence by psychiatric patients, ...

https://doi.org/10.1176/ajp.154.9.1272

Publication date: 01 September 1997

Pages1277–1284

OBJECTIVE: Fluctuating motor and vocal tics are the diagnostic feature of Tourette's disorder. The pathophysiology of tics is still unclear. One major hypothesis is a deficient inhibitory control through the cortical-striatal-thalamic-cortical motor loop. ...

https://doi.org/10.1176/ajp.154.9.1277

Publication date: 01 September 1997

Pages1293–1295

OBJECTIVE: The purpose of this study was to determine whether combined treatment with a selective serotonin reuptake inhibitor (SSRI) and a norepinephrine reuptake inhibitor, desipramine, effectively reduces obsessive-compulsive symptoms in patients who ...

https://doi.org/10.1176/ajp.154.9.1293

Publication date: 01 September 1997

Pages1296–1298

OBJECTIVE: The authors tested the hypothesis that photic visual stimuli cause a greater blood flow activation response in subjects with schizophrenia than in normal subjects. METHOD: Eleven medicated patients with schizophrenia and 10 normal subjects were ...

https://doi.org/10.1176/ajp.154.9.1296

Publication date: 01 September 1997

Pages1299–1301

OBJECTIVE: The authors compared the clinical characteristics and family history of patients with early-onset (before age 18), typical-onset (at 20-25 years), and late-onset (after age 35) affective psychosis at the time of first hospitalization. METHOD: ...

https://doi.org/10.1176/ajp.154.9.1299

Publication date: 01 September 1997

Pages1302–1304

OBJECTIVE: This study describes medication compliance rates among a group of homeless mentally ill subjects who received assertive community treatment. METHOD: The medication compliance of 77 homeless persons who had been referred to an assertive ...

https://doi.org/10.1176/ajp.154.9.1302

Publication date: 01 September 1997

Pages1305–1307

OBJECTIVE: The purpose of this study was to examine DSM-III-R axis I and axis II comorbidity in psychiatrically hospitalized young adults with substance use disorders. METHOD: Structured diagnostic interviews were given to 117 consecutive inpatients. ...

https://doi.org/10.1176/ajp.154.9.1305

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