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American Journal of Psychiatry

  • Volume 125
  • Number 4
  • October 1968

Article

Publication date: 01 October 1968

Pages445–457

The question posed by the title of this paper has been debated in the psychiatric literature both here and abroad for many years, as evidenced by such distinctions as endogenous vs. psychogenic or reactive, and psychotic vs. neurotic, forms of depression. ...

https://doi.org/10.1176/ajp.125.4.445

Publication date: 01 October 1968

Pages458–472

In this paper the author attempts to connect theory, general programmatic approaches, and specific programs related to family-oriented preventive programs in a systematic and meaningful way. His theoretical framework views the family as a flexible social ...

https://doi.org/10.1176/ajp.125.4.458

Publication date: 01 October 1968

Pages473–481

To examine the diagnostic and therapeutic significance of the EEG pattern called 14 and 6 per second positive spiking, when it occurs in patients with behavior disorders, the authors studied 78 adolescent and young adult inpatients. Although they did find ...

https://doi.org/10.1176/ajp.125.4.473

Publication date: 01 October 1968

Pages482–486

The authors describe the somewhat unexpected results they obtained by questioning psychiatric residents, nurses, and patients about what they thought had been helpful during psychiatric hospitalization. Nursing was mentioned frequently by patients, rarely ...

https://doi.org/10.1176/ajp.125.4.482

Publication date: 01 October 1968

Pages487–491

A double-blind study involving 29 patients was designed to investigate the efficacy of lithium compared with imipramine in the treatment of acute endogenous depression. After two to three weeks, there was evidence of a moderate to strong antidepressant ...

https://doi.org/10.1176/ajp.125.4.487

Publication date: 01 October 1968

Pages492–498

In a longitudinal outpatient study, the authors found that lithium produced a mild decrease in depth of depression scores among patients who had been on the drug for more than seven months, as compared with patients who had been receiving lithium less ...

https://doi.org/10.1176/ajp.125.4.492

Publication date: 01 October 1968

Pages499–512

A longitudinal double-blind study of two manic patients treated in a random fashion with lithium carbonate and placebo is reported. Daily ratings of mania were recorded independently by a trained psychiatric nursing team and by a psychiatrist. The major ...

https://doi.org/10.1176/ajp.125.4.499

Publication date: 01 October 1968

Pages512–519

The authors review the evidence for their conclusion that acutely manic patients retain more lithium ion and distribute it differently in the total body water than do normothymic patients. The pattern of lithium ion retention and distribution was studied ...

https://doi.org/10.1176/ajp.125.4.512

Publication date: 01 October 1968

Pages520–527

The increasing use of lithium in the treatment of manic-depressive disorder raises the risk of poisoning, either by mismanagement of treatment or by accident. The authors report on the prodromes, clinical pictures, and outcomes of eight cases of lithium ...

https://doi.org/10.1176/ajp.125.4.520

Publication date: 01 October 1968

Pages527–530

The authors report a possible long-termn side effect of lithium treatment in cases of manic-depressive disease. They examined 19 manic-depressive patients who had been on long-term lithium carbonate therapy and found that six had goiters and four others ...

https://doi.org/10.1176/ajp.125.4.527

Publication date: 01 October 1968

Pages530–536

Two sets of experiments were conducted to study the effects of lithium on the gross electrical activity of the cat brain. The first series, designed to study acute effects by means of recording evoked potentials using encephale isolé cats, suggests that ...

https://doi.org/10.1176/ajp.125.4.530

Publication date: 01 October 1968

Pages536–543

Lithium carbonate was administered to normal controls and to manic-depressive patients under carefully controlled conditions. Particular attention was given to diet. The authors found that lithium clearly affects the metabolism of sodium and calcium and, ...

https://doi.org/10.1176/ajp.125.4.536

Publication date: 01 October 1968

Pages544–548

Lithium was successfully used to treat five patients with recurrent depressions, three of whom had typical manic-depressive illnesses. Their clinical and also their characteristic subjective responses to lithium establish a very suggestive relationship ...

https://doi.org/10.1176/ajp.125.4.544

Publication date: 01 October 1968

Pages549–555

Lithium carbonate has been widely acclaimed as a useful drug in the treatment of manic-depressive psychoses. The results of this clinical study emphasize that lithium is highly beneficial in preventing and alleviating acute mania and the hypomanic aspects ...

https://doi.org/10.1176/ajp.125.4.549

Publication date: 01 October 1968

Pages562–569

In response to the need for standardization of methodology in assessing the side effects of psychotropic drugs, the authors describe a rating scale, structured for computer optical reading, to measure changes in physical and laboratory data. They feel ...

https://doi.org/10.1176/ajp.125.4.562

Publication date: 01 October 1968

Pages570–572

During an examination for competency to stand trial, the authors were impressed with a patient's "hypercompetency"—in this case, his extensive knowledge of the legal process. This observation, along with others, substantiated a diagnosis of paranoid ...

https://doi.org/10.1176/ajp.125.4.570

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