American Journal of Psychiatry
- Volume 179
- Number 4
- April 2022
Editor’s Note
Editorials
Reviews and Overviews
Publication date: 01 April 2022
Pages267–276The major cause of disability in schizophrenia is cognitive impairment, which remains largely refractory to existing treatments. This reflects the fact that antipsychotics and other therapies have not been designed to address specific brain abnormalities ...
https://doi.org/10.1176/appi.ajp.20220147Articles
Publication date: 01 April 2022
Pages277–287Objective: Cognitive impairments in schizophrenia are associated with lower gamma oscillation power in the prefrontal cortex (PFC). Gamma power depends in part on excitatory drive to fast-spiking parvalbumin interneurons (PVIs). Excitatory drive to ...
https://doi.org/10.1176/appi.ajp.2021.21080798Publication date: 01 April 2022
Pages288–297Objective: Determining the extent to which relationships between duration of untreated psychosis (DUP) and outcome endure longitudinally across the lifetime course of psychotic illness requires prospective, systematic studies of epidemiologically ...
https://doi.org/10.1176/appi.ajp.2021.20111658Publication date: 01 April 2022
Pages298–304Objective: Understanding the effectiveness of medication treatment for opioid use disorder to decrease the risk of suicide mortality may inform clinical and policy decisions. The authors sought to describe the effect of medications for opioid use disorder (...
https://doi.org/10.1176/appi.ajp.2021.21070700Publication date: 08 December 2021
Pages305–311Objective: The authors examined directly whether county-level changes in opioid dispensing rates affect individual-level prescription opioid misuse, frequency of use, and dependence, as well as the same outcomes for heroin. Methods: Using data from the ...
https://doi.org/10.1176/appi.ajp.2021.21060602Other Items Of Interest
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Vol. 181 | No. 12
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Vol. 181 | No. 10
