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American Journal of Psychiatry

  • Volume 179
  • Number 4
  • April 2022

Editor’s Note

Editorials

Reviews and Overviews

Publication date: 01 April 2022

Pages267–276

The major cause of disability in schizophrenia is cognitive impairment, which remains largely refractory to existing treatments. This reflects the fact that antipsychotics and other therapies have not been designed to address specific brain abnormalities ...

https://doi.org/10.1176/appi.ajp.20220147

Articles

Publication date: 01 April 2022

Pages277–287

Objective: Cognitive impairments in schizophrenia are associated with lower gamma oscillation power in the prefrontal cortex (PFC). Gamma power depends in part on excitatory drive to fast-spiking parvalbumin interneurons (PVIs). Excitatory drive to ...

https://doi.org/10.1176/appi.ajp.2021.21080798

Publication date: 01 April 2022

Pages288–297

Objective: Determining the extent to which relationships between duration of untreated psychosis (DUP) and outcome endure longitudinally across the lifetime course of psychotic illness requires prospective, systematic studies of epidemiologically ...

https://doi.org/10.1176/appi.ajp.2021.20111658

Publication date: 01 April 2022

Pages298–304

Objective: Understanding the effectiveness of medication treatment for opioid use disorder to decrease the risk of suicide mortality may inform clinical and policy decisions. The authors sought to describe the effect of medications for opioid use disorder (...

https://doi.org/10.1176/appi.ajp.2021.21070700

Publication date: 08 December 2021

Pages305–311

Objective: The authors examined directly whether county-level changes in opioid dispensing rates affect individual-level prescription opioid misuse, frequency of use, and dependence, as well as the same outcomes for heroin. Methods: Using data from the ...

https://doi.org/10.1176/appi.ajp.2021.21060602

Other Items Of Interest

Past Issues

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No.11
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1 Nov 2024

Vol. 181 | No. 11

No.10
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1 Oct 2024

Vol. 181 | No. 10

No.9
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1 Sep 2024

Vol. 181 | No. 9

No.8
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1 Aug 2024

Vol. 181 | No. 8