American Journal of Psychiatry
- Volume 179
- Number 8
- August 2022
Editor’s Note
Editorials
Reviews and Overviews
Publication date: 01 August 2022
Pages528–543Neuropsychiatric symptoms of dementia (NPS) are a group of noncognitive symptoms that occur in over 90% of individuals with dementia. NPS seem to result from a complex interaction among various biological, psychosocial, and environmental factors, and they ...
https://doi.org/10.1176/appi.ajp.20220508Articles
Publication date: 26 May 2022
Pages544–552Objective: The Veterans Health Administration (VHA) and the Centers for Medicare and Medicaid Services (CMS) each created initiatives to reduce off-label use of antipsychotics in patients with dementia in nursing homes. Although CMS has reported ...
https://doi.org/10.1176/appi.ajp.21060591Publication date: 15 June 2022
Pages553–561Objective: Pimavanserin, a serotonin 5-HT2 antagonist, is indicated for treatment of hallucinations and delusions associated with Parkinson’s disease psychosis. In premarketing trials in patients with Parkinson’s disease psychosis, 11% of patients died ...
https://doi.org/10.1176/appi.ajp.21090876Publication date: 25 March 2022
Pages562–572Objective: Previous research has demonstrated that the amygdala is enlarged in children with autism spectrum disorder (ASD). However, the precise onset of this enlargement during infancy, how it relates to later diagnostic behaviors, whether the timing of ...
https://doi.org/10.1176/appi.ajp.21090896Publication date: 26 May 2022
Pages573–585Objective: Autism spectrum disorder (ASD) is heritable, and younger siblings of ASD probands are at higher likelihood of developing ASD themselves. Prospective MRI studies of siblings report that atypical brain development precedes ASD diagnosis, although ...
https://doi.org/10.1176/appi.ajp.21101002