Focus
- Volume 10
- Number 4
- October 2012
From the Guest Editors
Clinical Synthesis
Publication date: 01 October 2012
Pages413–421This review of emerging data linking inflammatory processes to the pathophysiology and treatment of njor depressive disorder exemplifies how the field is moving forward from historically bound, monoamine-based hypotheses.
https://doi.org/10.1176/appi.focus.10.4.413Publication date: 01 October 2012
Pages422–427Chronic forms of depression have been closely studied over the last three decades, and it is now widely recognized that these conditions are better classified under the umbrella of affective disorders rather than characterological or personality ...
https://doi.org/10.1176/appi.focus.10.4.422Publication date: 01 October 2012
Pages428–433Major depressive disorder is one of the leading causes of disability in the world. Effective treatment guidelines have been developed and disseminated; however, unlike other fields of medicine, psychiatry has been slow to adapt and utilize these ...
https://doi.org/10.1176/appi.focus.10.4.428Publication date: 01 October 2012
Pages434–441In recent years, depression has been reconceptualized from a short, self-limiting condition to longer time frames as a result of the observation that most depressed persons will have a recurrent or chronic course.
https://doi.org/10.1176/appi.focus.10.4.434Publication date: 01 October 2012
Pages442–451Over the past two decades, the number of somatic treatments for psychiatric disorders has expanded, leading to new insights into the complex relationship between chemical and electric transmission of signals in the brain. In this article, the authors ...
https://doi.org/10.1176/appi.focus.10.4.442Publication date: 01 October 2012
Pages452–460After years of emphasizing the same monoamine-based neurotransmitter mechanisms for treating depression, the antidepressant medication pipeline is broadening its reach. Researchers are working on compounds targeting receptors in novel ways, as well as ...
https://doi.org/10.1176/appi.focus.10.4.452Publication date: 01 October 2012
Pages473–480The APA's Performance in Practice modules are guided practice improvement programs created for psychiatrists, designed to meet Part 4 MOC requirements for clinical modules. Modules follow a three-stage Performance Improvement CME structure that takes ...
https://doi.org/10.1176/appi.focus.10.4.473Influential Publications
Publication date: 01 October 2012
Pages489–491SummaryMindfulness-based cognitive therapy (MBCT) was developed as a psychological approach for people at risk for depressive relapse who wish to learn how to stay well in the long-term. In this article we set out the rationale for MBCT, outline the ...
https://doi.org/10.1176/appi.focus.10.4.489Publication date: 01 October 2012
Pages492–505ObjectiveTwo antidepressant medication combinations were compared with selective serotonin reuptake inhibitor monotherapy to determine whether either combination produced a higher remission rate in first-step acute-phase (12 weeks) and long-term (7 months)...
https://doi.org/10.1176/appi.focus.10.4.492Publication date: 01 October 2012
Pages510–517Abstract:The authors provide an overview of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study (www.star-d.org), a large-scale practical clinical trial to determine which of several treatments are the most effective “next-steps” for ...
https://doi.org/10.1176/appi.focus.10.4.510Past Issues
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