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American Journal of Psychiatry

  • Volume 177
  • Number 5
  • May 2020

Editor’s Note

Editorials

Reviews and Overviews

Publication date: 01 May 2020

Pages381–390

The search for more effective treatments for depression is a long-standing primary objective in both psychiatry and translational neuroscience. From initial models centered on neurochemical deficits, such as the monoamine hypothesis, research toward this ...

https://doi.org/10.1176/appi.ajp.2020.20030280

Publication date: 26 February 2020

Pages391–410

Objective: The authors provide an evidenced-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders. Methods: Searches of PubMed and PsycINFO via Ovid were conducted for articles in English, in peer-reviewed ...

https://doi.org/10.1176/appi.ajp.2019.19010035

Articles

Publication date: 22 January 2020

Pages411–421

Objective: Disrupted emotional processing is a common feature of many psychiatric disorders. The authors investigated functional disruptions in neural circuitry underlying emotional processing across a range of tasks and across psychiatric disorders ...

https://doi.org/10.1176/appi.ajp.2019.18111271

Publication date: 26 February 2020

Pages422–434

Objective: Imaging studies of major depressive disorder have reported structural and functional abnormalities in a variety of spatially diverse brain regions. Quantitative meta-analyses of this literature, however, have failed to find statistically ...

https://doi.org/10.1176/appi.ajp.2019.19050560

Publication date: 12 March 2020

Pages435–446

Objective: Treatment of different depression symptoms may require different brain stimulation targets with different underlying brain circuits. The authors sought to identify such targets, which could improve the efficacy of therapeutic brain stimulation ...

https://doi.org/10.1176/appi.ajp.2019.19090915

Publication date: 28 April 2020

Pages447–453

Objective: The authors sought to clarify the role of rearing environment in the etiology of major depression. Methods: Defining high risk as having at least one biological parent with major depression, the authors identified a Swedish National Sample of 666 ...

https://doi.org/10.1176/appi.ajp.2019.19090911

Publication date: 07 April 2020

Pages454–463

Objective: Although both pediatric and adult patients with anxiety disorders exhibit similar neural responding to threats, age-related differences have been found in some functional MRI (fMRI) studies. To reconcile disparate findings, the authors compared ...

https://doi.org/10.1176/appi.ajp.2019.19060650

Letters to the Editor

Books Received

Past Issues

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No.11
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1 Nov 2024

Vol. 181 | No. 11

No.10
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1 Oct 2024

Vol. 181 | No. 10

No.9
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1 Sep 2024

Vol. 181 | No. 9

No.8
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1 Aug 2024

Vol. 181 | No. 8