American Journal of Psychiatry
- Volume 177
- Number 5
- May 2020
Editor’s Note
Editorials
Reviews and Overviews
Publication date: 01 May 2020
Pages381–390The search for more effective treatments for depression is a long-standing primary objective in both psychiatry and translational neuroscience. From initial models centered on neurochemical deficits, such as the monoamine hypothesis, research toward this ...
https://doi.org/10.1176/appi.ajp.2020.20030280Publication date: 26 February 2020
Pages391–410Objective:The authors provide an evidenced-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders.Methods:Searches of PubMed and PsycINFO via Ovid were conducted for articles in English, in peer-reviewed ...
https://doi.org/10.1176/appi.ajp.2019.19010035Articles
Publication date: 22 January 2020
Pages411–421Objective:Disrupted emotional processing is a common feature of many psychiatric disorders. The authors investigated functional disruptions in neural circuitry underlying emotional processing across a range of tasks and across psychiatric disorders ...
https://doi.org/10.1176/appi.ajp.2019.18111271Publication date: 26 February 2020
Pages422–434Objective:Imaging studies of major depressive disorder have reported structural and functional abnormalities in a variety of spatially diverse brain regions. Quantitative meta-analyses of this literature, however, have failed to find statistically ...
https://doi.org/10.1176/appi.ajp.2019.19050560Publication date: 12 March 2020
Pages435–446Objective:Treatment of different depression symptoms may require different brain stimulation targets with different underlying brain circuits. The authors sought to identify such targets, which could improve the efficacy of therapeutic brain stimulation ...
https://doi.org/10.1176/appi.ajp.2019.19090915Publication date: 28 April 2020
Pages447–453Objective:The authors sought to clarify the role of rearing environment in the etiology of major depression.Methods:Defining high risk as having at least one biological parent with major depression, the authors identified a Swedish National Sample of 666 ...
https://doi.org/10.1176/appi.ajp.2019.19090911Publication date: 07 April 2020
Pages454–463Objective:Although both pediatric and adult patients with anxiety disorders exhibit similar neural responding to threats, age-related differences have been found in some functional MRI (fMRI) studies. To reconcile disparate findings, the authors compared ...
https://doi.org/10.1176/appi.ajp.2019.19060650Letters to the Editor
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