American Journal of Psychiatry
- Volume 181
- Number 5
- May 2024
Editor’s Note
Commentary
Reviews and Overviews
Publication date: 01 May 2024
Pages362–371Substance use disorders (SUD) present a worldwide challenge with few effective therapies except for the relative efficacy of opioid pharmacotherapies, despite limited treatment access. However, the proliferation of illicit fentanyl use initiated a ...
https://doi.org/10.1176/appi.ajp.20230828Publication date: 01 May 2024
Pages372–380Opioid overdose deaths and opioid-related harms have reached unprecedented levels, particularly as compounds such as xylazine and fentanyl have infiltrated the drug supply. Harm reduction strategies are especially relevant in this climate, as they aim to ...
https://doi.org/10.1176/appi.ajp.20230918Publication date: 01 May 2024
Pages381–390The fourth wave of the United States overdose crisis—driven by the polysubstance use of fentanyl with stimulants and other synthetic substances—has driven sharply escalating racial/ethnic inequalities in drug overdose death rates. Here the authors present ...
https://doi.org/10.1176/appi.ajp.20230917Publication date: 01 May 2024
Pages391–402Alcohol use disorder (AUD) and chronic pain disorders are pervasive, multifaceted medical conditions that often co-occur. However, their comorbidity is often overlooked, despite its prevalence and clinical relevance. Individuals with AUD are more likely ...
https://doi.org/10.1176/appi.ajp.20230886Articles
Publication date: 01 May 2024
Pages403–411Objective: There have been no well-controlled and well-powered comparative trials of topiramate with other pharmacotherapies for alcohol use disorder (AUD), such as naltrexone. Moreover, the literature is mixed on the effects of two polymorphisms—rs2832407 ...
https://doi.org/10.1176/appi.ajp.20230666Publication date: 01 May 2024
Pages412–422Objective: Stress and alcohol cue reactivity are associated with poor treatment outcomes in alcohol use disorder (AUD), but sex-specific neural correlates of stress and alcohol cue–induced craving compared with neutral cue–induced craving and of heavy ...
https://doi.org/10.1176/appi.ajp.20230849Publication date: 01 May 2024
Pages423–433Objective: Substance use initiation during early adolescence is associated with later development of substance use and mental health disorders. This study used various domains to predict substance use initiation, defined as trying any nonprescribed ...
https://doi.org/10.1176/appi.ajp.20230882Publication date: 01 May 2024
Pages434–444Objective: The co-occurrence of unhealthy alcohol use and opioid misuse is high and associated with increased rates of overdose, emergency health care utilization, and death. The current study examined whether receipt of an alcohol-related brief ...
https://doi.org/10.1176/appi.ajp.20230683Publication date: 10 January 2024
Pages445–456Objective: Alcohol use disorder (AUD) constitutes a critical public health issue and has sex-specific characteristics. Initial evidence suggests that progesterone and estradiol might reduce or increase alcohol intake, respectively. However, there is a need ...
https://doi.org/10.1176/appi.ajp.20230027Priority Data Letter
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