American Journal of Psychiatry
- Volume 181
- Number 6
- June 2024
Editor’s Note
Editorials
Review and Overview
Publication date: 01 June 2024
Pages482–492Schizophrenia is routinely referred to as a neurodevelopmental disorder, but the role of brain development in a disorder typically diagnosed during early adult life is enigmatic. The authors revisit the neurodevelopmental model of schizophrenia with ...
https://doi.org/10.1176/appi.ajp.20240305Articles
Publication date: 02 November 2023
Pages493–511Objective: Schizophrenia is a brain disorder that originates during neurodevelopment and has complex genetic and environmental etiologies. Despite decades of clinical evidence of altered striatal function in affected patients, studies examining its ...
https://doi.org/10.1176/appi.ajp.20220723Publication date: 13 March 2024
Pages512–519Objective: Markers for treatment resistance in schizophrenia are needed to reduce delays in effective treatment. Nigrostriatal hyperdopaminergic function plays a critical role in the pathology of schizophrenia, yet antipsychotic nonresponders do not show ...
https://doi.org/10.1176/appi.ajp.20220780Publication date: 13 March 2024
Pages520–531Objective: Cognitive remediation provides substantial improvements in cognitive performance and real-world functioning for people living with schizophrenia, but the durability of these benefits needs to be reassessed and better defined. The aims of this ...
https://doi.org/10.1176/appi.ajp.20230396Publication date: 15 May 2024
Pages532–540Objective: Understanding prognosis is critical to anticipating public health needs and providing care to individuals with psychotic disorders. However, the long-term course of remission and recovery remains unclear. In this study, the most common ...
https://doi.org/10.1176/appi.ajp.20230189Publication date: 30 April 2024
Pages541–552Objective: To investigate shared and specific neural correlates of cognitive functions in attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), the authors performed a comprehensive meta-analysis and considered a balanced set ...
https://doi.org/10.1176/appi.ajp.20230270Publication date: 13 March 2024
Pages553–562Objective: A large body of functional MRI research has examined a potential role for subcortico-cortical loops in the pathogenesis of attention deficit hyperactivity disorder (ADHD), but has produced inconsistent findings. The authors performed a mega-...
https://doi.org/10.1176/appi.ajp.20230026