American Journal of Psychiatry
- Volume 169
- Number 12
- December 2012
In This Issue
Perspectives
Editorials
Publication date: 01 December 2012
Pages1233–1237The Editors offer their personal selections of the articles this year they found particularly interesting and important. Also available in Spanish.
https://doi.org/10.1176/appi.ajp.2012.12091250Perspectives
Treatment in Psychiatry
Publication date: 01 December 2012
Pages1238–1244ECT is often effective for severely depressed patients who have not responded to multiple medication trials or who are at imminent risk of suicide. This issue's Treatment in Psychiatry highlights the safety and efficacy of ECT while stressing the ...
https://doi.org/10.1176/appi.ajp.2012.12050648Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 December 2012
Pages1247–1255Objective The author reviewed prospective longitudinal studies of the offspring of parents with bipolar disorder to inform our understanding of the nature of the association between childhood ADHD and the risk of developing bipolar disorder in adolescence ...
https://doi.org/10.1176/appi.ajp.2012.11111725Publication date: 01 December 2012
Pages1256–1266Objective The existence of comorbidity between attention deficit hyperactivity disorder (ADHD) and bipolar I disorder has been documented in clinical and epidemiological studies, in studies of children and adults, and in diagnosed ADHD and bipolar I ...
https://doi.org/10.1176/appi.ajp.2012.12010087New Research
Articles
Publication date: 01 December 2012
Pages1267–1274Patients with major depression who have an insufficient response to selective serotonin reuptake inhibitors (SSRIs) may benefit from the addition of 15 mg/day of l-methylfolate, the only form of folate that crosses the blood-brain barrier. Adding 7.5 mg/...
https://doi.org/10.1176/appi.ajp.2012.11071114Publication date: 01 December 2012
Pages1275–1283Objective The authors sought to directly examine compromises in the semantic system in mild cognitive impairment and their possible relationship to everyday functional competencies. Method Study participants were 25 patients who met criteria for amnestic ...
https://doi.org/10.1176/appi.ajp.2012.12030383Publication date: 01 December 2012
Pages1284–1291Objective It has been estimated that 10%–20% of U.S. veterans of the wars in Iraq and Afghanistan experienced mild traumatic brain injury (TBI), mostly secondary to blast exposure. Diffusion tensor imaging (DTI) may detect subtle white matter changes in ...
https://doi.org/10.1176/appi.ajp.2012.12050600Publication date: 01 December 2012
Pages1292–1300Objective Immunopathogenic mechanisms have been implicated in schizophrenia and bipolar disorder, and genome-wide association studies (GWAS) point to the major histocompatibility complex, a region that contains many immune-related genes. One of the ...
https://doi.org/10.1176/appi.ajp.2012.11091431Publication date: 01 December 2012
Pages1301–1308Objective The single-nucleotide polymorphism rs1344706, located within an intron of the ZNF804A gene, exhibits genome-wide significant association with schizophrenia. Although genotype at rs1344706 is associated with altered functional brain connectivity, ...
https://doi.org/10.1176/appi.ajp.2012.11121845Publication date: 01 December 2012
Pages1309–1317Objective Multiple sources of evidence suggest that genetic factors influence variation in clinical features of schizophrenia. The authors present the first genome-wide association study (GWAS) of dimensional symptom scores among individuals with ...
https://doi.org/10.1176/appi.ajp.2012.12020218Communications and Updates
Letters to the Editor
Communications and Updates
Corrections
Communications and Updates
Book Forum
Communications and Updates
Books Received
Communications and Updates
In Appreciation
Publication date: 01 December 2012
Pages1327–1332https://doi.org/10.1176/appi.ajp.2012.16912reviewersPast Issues
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