American Journal of Psychiatry
- Volume 170
- Number 4
- April 2013
In This Issue
Perspectives
Editorials
Perspectives
Clinical Case Conference
Publication date: 01 April 2013
Pages366–369Late-onset agranulocytosis is rare during treatment with clozapine, especially in monotherapy. The authors describe a case of agranulocytosis that emerged after 19 years of continuous clozapine monotherapy. The discovery of the agranulocytosis was due to ...
https://doi.org/10.1176/appi.ajp.2012.12081036Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 April 2013
Pages372–382The hypothesis that rapid eye movement (REM) sleep disturbances are the hallmark of posttraumatic stress disorder (PTSD), proposed by Ross and colleagues in 1989, has stimulated a wealth of clinical, preclinical, and animal studies on the role of sleep in ...
https://doi.org/10.1176/appi.ajp.2012.12040432New Research
Articles
Publication date: 01 April 2013
Pages383–390Alcohol and drug use are known to increase the risk for traumatic brain injury (TBI), but the reverse was also true in this study of active-duty U.S. Air Force enlisted and officer personnel. A greater risk for alcohol and nicotine dependence and drug ...
https://doi.org/10.1176/appi.ajp.2012.12010126Publication date: 01 April 2013
Pages391–398Objective Understanding the relationship between fetal growth and autism spectrum disorder (ASD) is likely to advance the search for genetic and nongenetic causes of ASD. The authors explored the associations between fetal growth, gestational age, and ASD ...
https://doi.org/10.1176/appi.ajp.2012.12040543Publication date: 01 April 2013
Pages399–407Immunization with a nicotine conjugate vaccine (3′-AmNic-rEPA) significantly reduced nicotine’s ability to enter the brain and bind to β2-containing nicotinic acetylcholine receptors (β2*-nAChRs) by sequestering nicotine in the blood. Healthy tobacco ...
https://doi.org/10.1176/appi.ajp.2012.12060793Early Smoking Onset and Risk for Subsequent Nicotine Dependence: A Monozygotic Co-Twin Control Study
Publication date: 01 April 2013
Pages408–413Objective Early onset of regular smoking is associated with an elevated risk for later nicotine dependence. Whether or not this association is causal is unknown and has substantial public policy implications. Method The authors used a monozygotic co-twin ...
https://doi.org/10.1176/appi.ajp.2012.12030321Publication date: 01 April 2013
Pages414–425Using telemedicine technologies, off-site mental health specialists collaborating with on-site primary care physicians yielded better depression outcomes than practice-based care with staff available on-site. In this study of mostly rural, unemployed, and ...
https://doi.org/10.1176/appi.ajp.2012.12050696Publication date: 01 April 2013
Pages426–433Objective The relationship between depression and estrogen withdrawal remains controversial. The authors examined the effects of gonadotropin-releasing hormone agonist-induced ovarian suppression on mood, sleep, sexual function, and nighttime hot flushes. ...
https://doi.org/10.1176/appi.ajp.2012.12010117Publication date: 01 April 2013
Pages434–441Objective Understanding the origins of negative cognitive style could provide a means to prevent adult depression. Cognitive style is an important target for intervention because although it is not possible to remove the stress and adversities in people’s ...
https://doi.org/10.1176/appi.ajp.2012.12050673