American Journal of Psychiatry
- Volume 175
- Number 3
- March 2018
Editorials
Images in Psychiatry
Clinical Case Conference
Reviews and Overviews
Publication date: 05 December 2017
Pages215–224Recent research has linked age-related hearing loss to impaired performance across cognitive domains and increased risk for dementia diagnosis. The data linking hearing impairment to incident late-life depression are more mixed but suggest that diminished ...
https://doi.org/10.1176/appi.ajp.2017.17040423Articles
Publication date: 15 December 2017
Pages225–231Objective: Research in both animals and humans indicates that cannabidiol (CBD) has antipsychotic properties. The authors assessed the safety and effectiveness of CBD in patients with schizophrenia. Method: In an exploratory double-blind parallel-group trial,...
https://doi.org/10.1176/appi.ajp.2017.17030325Publication date: 28 November 2017
Pages232–241Objective: Depression is associated with an increased risk of Alzheimer’s disease. Research has shown that the selective serotonin reuptake inhibitor (SSRI) citalopram decreases amyloid-β generation and plaque load. The authors evaluated the impact of SSRI ...
https://doi.org/10.1176/appi.ajp.2017.17040404Publication date: 03 October 2017
Pages242–250Objective: The authors evaluated the efficacy and durability of a therapist-supported method for computer-assisted cognitive-behavioral therapy (CCBT) in comparison to standard cognitive-behavioral therapy (CBT). Method: A total of 154 medication-free ...
https://doi.org/10.1176/appi.ajp.2017.17010089Publication date: 15 December 2017
Pages251–261Objective: Genetic variation within the hypothalamic-pituitary-adrenal (HPA) axis has been linked to risk for depression and antidepressant response. However, these associations have yet to produce clinical gains that inform treatment decisions. The ...
https://doi.org/10.1176/appi.ajp.2017.17020172Publication date: 24 January 2018
Pages262–274Objective: Proinflammatory cytokines have recently received considerable attention for their role in suicidal behavior; however, how the expression of cytokine genes is regulated is not clearly known. The authors examined underlying mechanisms of critical ...
https://doi.org/10.1176/appi.ajp.2017.16070759Publication date: 05 December 2017
Pages275–283Objective: Although patients with schizophrenia exhibit impaired suppression of the P50 event-related brain potential in response to the second of two identical auditory stimuli during a paired-stimulus paradigm, uncertainty remains over whether this ...
https://doi.org/10.1176/appi.ajp.2017.16111203