Focus
- Volume 14
- Number 2
- April 2016
From the Guest Editor
Clinical Synthesis
Publication date: 01 April 2016
Pages156–173Combination treatment with psychotherapy and antidepressant medication can be provided from the initiation of treatment, sequentially after nonremission with a single-modality treatment or sequentially after remission to buttress the patient’s recovery to ...
https://doi.org/10.1176/appi.focus.20150042Publication date: 01 April 2016
Pages174–179A number of high-intensity psychosocial interventions have been shown to be as efficacious as and more enduring than medications in the treatment of nonpsychotic depression. Moreover, there have been important advances in the development of strategies to ...
https://doi.org/10.1176/appi.focus.20150044Publication date: 01 April 2016
Pages180–183Depressive episodes that do not respond to at least several adequate courses of standard antidepressants account for a substantial proportion of the socioeconomic and medical burden associated with this common illness. As such, treatment-resistant ...
https://doi.org/10.1176/appi.focus.20150041Publication date: 01 April 2016
Pages184–193Depression and diabetes are common, chronic, and frequently comorbid diseases that contribute substantially to global disability and mortality. Their relationship is bidirectional: depression increases the risk of developing type 2 diabetes mellitus (T2DM)...
https://doi.org/10.1176/appi.focus.20150040Publication date: 01 April 2016
Pages194–206Cognitive dysfunction is increasingly being recognized as an important clinical dimension in major depressive disorder. This review summarizes the existing data on the epidemiology, assessment, and treatment of cognitive dysfunction among nonelderly ...
https://doi.org/10.1176/appi.focus.20150043Ask the Expert
Patient Management Exercise
Ethics Commentary
Communication Commentary
Safety Commentary
Bibliography
Abstracts
Influential Publications
Publication date: 01 April 2016
Pages229–243Background: Previous meta-analyses comparing the efficacy of psychotherapeutic interventions for depression were clouded by a limited number of within-study treatment comparisons. This study used network meta-analysis, a novel methodological approach that ...
https://doi.org/10.1176/appi.focus.140201Publication date: 01 April 2016
Pages244–265Background: Atypical antipsychotic medications are widely prescribed for the adjunctive treatment of depression, yet their total risk–benefit profile is not well understood. We thus conducted a systematic review of the efficacy and safety profiles of ...
https://doi.org/10.1176/appi.focus.140202Publication date: 01 April 2016
Pages266–276In this Seminar we discuss developments from the past 5 years in the diagnosis, neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and medical comorbidity have been emphasised as important factors in improving the ...
https://doi.org/10.1176/appi.focus.140208Publication date: 01 April 2016
Pages277–282Background: A few studies have examined the durability of transcranial magnetic stimulation (TMS) antidepressant benefit once patients remitted. This study examined the long-term durability of clinical benefit from TMS using a protocol-specified TMS taper ...
https://doi.org/10.1176/appi.focus.140204Past Issues
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