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American Journal of Psychiatry

  • Volume 171
  • Number 4
  • April 2014

In This Issue

Perspectives

Editorials

Perspectives

Commentary

Perspectives

Clinical Case Conference

Perspectives

Images in Psychiatry

Perspectives

Reviews and Overviews

Publication date: 01 April 2014

Pages404–415

There are no strategies yet for preventing antidepressant-induced adverse hepatic events, but early detection by aminotransferase surveillance is essential, as drug-induced liver injury from antidepressants, although rare, may be irreversible in at-risk ...

https://doi.org/10.1176/appi.ajp.2013.13050709

New Research

Articles

Publication date: 01 April 2014

Pages416–425

Adolescent rhesus monkeys administered D9-tetrahydrocannabinol (THC) 5 days a week for 6 months showed less practice-related improvement than unexposed monkeys on a test measuring working memory of spatial relationships. The exposed and unexposed monkeys ...

https://doi.org/10.1176/appi.ajp.2013.13030335

Publication date: 01 April 2014

Pages426–435

Personality and failures in interpersonal relationships play a stronger etiologic role in major depression for women, but childhood sexual abuse, externalizing psychopathology, prior depression, and acute financial, occupational, or legal stress were ...

https://doi.org/10.1176/appi.ajp.2013.13101375

Publication date: 01 April 2014

Pages436–444

Computer-based training for cognitive-behavioral therapy (CBT4CBT) can increase abstinence rates in patients with cocaine dependence enrolled in methadone maintenance and weekly group sessions. The 47 patients randomly assigned to CBT4CBT completed five ...

https://doi.org/10.1176/appi.ajp.2013.13070987

Publication date: 01 April 2014

Pages445–452

Heavy drinkers trying to cut back but not completely eliminate their alcohol intake were treated with topiramate as an adjunct to counseling and reduced their drinking more rapidly than patients given placebo. The effect of topiramate was significant only ...

https://doi.org/10.1176/appi.ajp.2013.13081014

Publication date: 01 April 2014

Pages453–462

The mechanisms linking depression to mortality were found to be related to biological dysregulations or lifestyle factors rather than disease specific in this unprecedented meta-analysis of 247 studies—which included 105,986 depressed and 578,503 ...

https://doi.org/10.1176/appi.ajp.2013.13030325

Publication date: 01 April 2014

Pages463–469

A head injury, especially a severe head injury or one occurring between the ages of 11 and 15, increased the risk for subsequent schizophrenia by 65%, the risk of depression by 59%, the risk of bipolar disorder by 28%, and the risk of organic mental ...

https://doi.org/10.1176/appi.ajp.2013.13020190

Communications and Updates

Book Forum

Communications and Updates

Books Received

Past Issues

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