Site maintenance Wednesday, November 13th, 2024. Please note that access to some content and account information will be unavailable on this date.
Skip to main content
Skip to Footer

American Journal of Psychiatry

  • Volume 178
  • Number 12
  • December 2021

Editor's Note

Editorials

Reviews and Overviews

Publication date: 01 December 2021

Pages1082–1088

For many decades, psychiatric treatment has been primarily guided by two major paradigms of psychopathology: a neurochemical paradigm leading to the development of medications and a psychological paradigm resulting in the development of psychotherapies. A ...

https://doi.org/10.1176/appi.ajp.2021.21101034

Articles

Publication date: 10 September 2021

Pages1089–1097

Objective: This observational study examined the effects of electroconvulsive therapy (ECT) on suicide and all-cause mortality risk in older psychiatric patients. Methods: Participants were Medicare-insured psychiatric inpatients age 65 or older. ...

https://doi.org/10.1176/appi.ajp.2021.21040351

Publication date: 23 September 2021

Pages1098–1106

Objective: In a phase 3 randomized double-blind placebo-controlled study, the authors investigated the efficacy and safety of 42 mg/day of lumateperone in patients with bipolar I or bipolar II disorder experiencing a major depressive episode. Methods: ...

https://doi.org/10.1176/appi.ajp.2021.20091339

Publication date: 14 October 2021

Pages1107–1118

Objective: Evidence from anti-inflammatory drug trials for the treatment of depression has been inconsistent. This may be ascribed to the differing symptom-specific effects of inflammation. Accordingly, the authors explored the associations between ...

https://doi.org/10.1176/appi.ajp.2021.20121776

Publication date: 14 October 2021

Pages1119–1128

Objective: Structural neuroimaging findings in younger and older adults with major depressive disorder (MDD) are highly heterogeneous, possibly as a result of methodological limitations, lack of distinction between MDD and late-life depression (LLD), or ...

https://doi.org/10.1176/appi.ajp.2021.21010088

Letters to the Editor

Appreciation

Past Issues

View Issues Archive
No.11
View Issue
1 Nov 2024

Vol. 181 | No. 11

No.10
View Issue
1 Oct 2024

Vol. 181 | No. 10

No.9
View Issue
1 Sep 2024

Vol. 181 | No. 9

No.8
View Issue
1 Aug 2024

Vol. 181 | No. 8