American Journal of Psychiatry
- Volume 180
- Number 10
- October 2023
Editor’s Note
Editorials
Commentary
Articles
Publication date: 30 August 2023
Pages714–722Objective:Major depressive disorder (MDD) is highly heterogeneous. Standard typology partly captures the disorder’s symptomatic heterogeneity, although whether it adequately captures etiological heterogeneity remains elusive. The aim of this study was to ...
https://doi.org/10.1176/appi.ajp.20220906Publication date: 01 October 2023
Pages723–738Objective:Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale genome-wide association studies (GWASs) recently discovered and cross-validated genome-wide significant (GWS) loci for suicide attempt (SA). The present ...
https://doi.org/10.1176/appi.ajp.21121266Publication date: 26 July 2023
Pages739–754Objective:Multidisciplinary studies of posttraumatic stress disorder (PTSD) and major depressive disorder (MDD) implicate the dorsolateral prefrontal cortex (DLPFC) in disease risk and pathophysiology. Postmortem brain studies have relied on bulk-tissue ...
https://doi.org/10.1176/appi.ajp.20220478Publication date: 16 August 2023
Pages755–765Objective:Previous population-based studies have identified associations between childhood neurodevelopmental traits and depression in childhood, adolescence, and young adulthood. However, neurodevelopmental traits are highly correlated with each other, ...
https://doi.org/10.1176/appi.ajp.20220868Publication date: 06 September 2023
Pages766–777Objective:Maternal psychological stress during pregnancy is a common risk factor for psychiatric disorders in offspring, but little is known about how heterogeneity of stress trajectories during pregnancy affect brain systems and behavioral phenotypes in ...
https://doi.org/10.1176/appi.ajp.21111176Past Issues
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