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American Journal of Psychiatry

  • Volume 165
  • Number 12
  • December 2008

In This Issue

Editorial

Commentary

Introspection

Treatment in Psychiatry

Clinical Case Conference

Images in Psychiatry

Reviews and Overviews

Publication date: 01 December 2008

Pages1532–1542

Objective: OCD is a clinically heterogeneous condition. This heterogeneity has the potential to reduce power in genetic, neuroimaging, and clinical trials. Despite a mounting number of studies, there remains debate regarding the exact factor ...

https://doi.org/10.1176/appi.ajp.2008.08020320

Article

Publication date: 01 December 2008

Pages1543–1550

Objective: A prior depressive episode is thought to increase the risk of depression. However, among older adults with prior depression, it is unclear whether sleep disturbance predicts depression recurrence independent of other depressive ...

https://doi.org/10.1176/appi.ajp.2008.07121882

Publication date: 01 December 2008

Pages1551–1558

Objective: The purpose of this study was to test the hypothesis that disturbances in levels of plasma melatonin differentiate pregnant and postpartum women with major depression from matched pregnant and postpartum healthy comparison women. ...

https://doi.org/10.1176/appi.ajp.2008.08050709

Publication date: 01 December 2008

Pages1559–1565

Objective: Recent studies demonstrate the poor psychosocial outcomes associated with bipolar disorder. Occupational functioning, a key indicator of psychosocial disability, is often severely affected by the disorder. The authors describe the ...

https://doi.org/10.1176/appi.ajp.2008.07121953

Publication date: 01 December 2008

Pages1566–1575

Objective: Despite increased risk for psychiatric disorders after trauma exposure, many people are able to adapt with minimal life disruption, and others eventually recover after a symptomatic period. This study examined psychosocial factors ...

https://doi.org/10.1176/appi.ajp.2008.07121939

Publication date: 01 December 2008

Pages1576–1584

Objective: The authors previously identified a haplotype on chromosome 6p22 defined by three single-nucleotide polymorphisms (SNPs) that was associated with dyslexia (reading disability) in two independent samples of families that included at ...

https://doi.org/10.1176/appi.ajp.2008.07121872

Publication date: 01 December 2008

Pages1585–1593

Objective: Deficits in working memory and cognitive control in schizophrenia are associated with impairments in prefrontal cortical function, including altered gamma band oscillations. These abnormalities are thought to reflect a deficiency in ...

https://doi.org/10.1176/appi.ajp.2008.08030395

Publication date: 01 December 2008

Pages1594–1603

Objective: Deficits in gamma-aminobutyric acid (GABA) signaling have been described in the prefrontal cortex, limbic system, and cerebellum in individuals with schizophrenia. The purpose of the present study was to further investigate ...

https://doi.org/10.1176/appi.ajp.2008.07121845

Publication date: 01 December 2008

Pages1604–1610

Objective: The authors tested the hypothesis that either prenatal feminization or masculinization hormone influences in utero or later socialization affects the risk for anorexia and bulimia nervosa and disordered eating in members of opposite-...

https://doi.org/10.1176/appi.ajp.2008.08030362

Letters to the Editor

Correction

Book Forum

Books Received

Annual Author Index

In Appreciation

Past Issues

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