American Journal of Psychiatry
- Volume 165
- Number 12
- December 2008
In This Issue
Editorial
Commentary
Introspection
Treatment in Psychiatry
Clinical Case Conference
Images in Psychiatry
Reviews and Overviews
Publication date: 01 December 2008
Pages1532–1542Objective: OCD is a clinically heterogeneous condition. This heterogeneity has the potential to reduce power in genetic, neuroimaging, and clinical trials. Despite a mounting number of studies, there remains debate regarding the exact factor ...
https://doi.org/10.1176/appi.ajp.2008.08020320Article
Publication date: 01 December 2008
Pages1543–1550Objective: A prior depressive episode is thought to increase the risk of depression. However, among older adults with prior depression, it is unclear whether sleep disturbance predicts depression recurrence independent of other depressive ...
https://doi.org/10.1176/appi.ajp.2008.07121882Publication date: 01 December 2008
Pages1551–1558Objective: The purpose of this study was to test the hypothesis that disturbances in levels of plasma melatonin differentiate pregnant and postpartum women with major depression from matched pregnant and postpartum healthy comparison women. ...
https://doi.org/10.1176/appi.ajp.2008.08050709Publication date: 01 December 2008
Pages1559–1565Objective: Recent studies demonstrate the poor psychosocial outcomes associated with bipolar disorder. Occupational functioning, a key indicator of psychosocial disability, is often severely affected by the disorder. The authors describe the ...
https://doi.org/10.1176/appi.ajp.2008.07121953Publication date: 01 December 2008
Pages1566–1575Objective: Despite increased risk for psychiatric disorders after trauma exposure, many people are able to adapt with minimal life disruption, and others eventually recover after a symptomatic period. This study examined psychosocial factors ...
https://doi.org/10.1176/appi.ajp.2008.07121939Publication date: 01 December 2008
Pages1576–1584Objective: The authors previously identified a haplotype on chromosome 6p22 defined by three single-nucleotide polymorphisms (SNPs) that was associated with dyslexia (reading disability) in two independent samples of families that included at ...
https://doi.org/10.1176/appi.ajp.2008.07121872Publication date: 01 December 2008
Pages1585–1593Objective: Deficits in working memory and cognitive control in schizophrenia are associated with impairments in prefrontal cortical function, including altered gamma band oscillations. These abnormalities are thought to reflect a deficiency in ...
https://doi.org/10.1176/appi.ajp.2008.08030395Publication date: 01 December 2008
Pages1594–1603Objective: Deficits in gamma-aminobutyric acid (GABA) signaling have been described in the prefrontal cortex, limbic system, and cerebellum in individuals with schizophrenia. The purpose of the present study was to further investigate ...
https://doi.org/10.1176/appi.ajp.2008.07121845Publication date: 01 December 2008
Pages1604–1610Objective: The authors tested the hypothesis that either prenatal feminization or masculinization hormone influences in utero or later socialization affects the risk for anorexia and bulimia nervosa and disordered eating in members of opposite-...
https://doi.org/10.1176/appi.ajp.2008.08030362