American Journal of Psychiatry
- Volume 169
- Number 7
- July 2012
In This Issue
Perspectives
Editorial
Perspectives
Clinical Case Conference
Publication date: 01 July 2012
Pages688–691PTSD and substance use disorder are often comorbid in combat veterans. Abstinence has been historically required before PTSD treatment, to maximize the effect of PTSD treatment and minimize the risk that psychologically challenging treatments, such as ...
https://doi.org/10.1176/appi.ajp.2011.11091433Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 July 2012
Pages693–703Objective: Functional neuroimaging investigations of major depressive disorder can advance both the neural theory and treatment of this debilitating illness. Inconsistency of neuroimaging findings and the use of region-of-interest approaches have hindered ...
https://doi.org/10.1176/appi.ajp.2012.11071105New Research
Articles
Publication date: 01 July 2012
Pages704–709Mechanisms to compensate insurance plans covering disproportionate numbers of chronically mentally ill patients in the planned health insurance exchanges are generally adequate, according to an analysis of past claims data. After implementation of the ...
https://doi.org/10.1176/appi.ajp.2012.11071044Publication date: 01 July 2012
Pages710–718Objective: Cognitive remediation is an efficacious treatment for schizophrenia and, when used within broader psychosocial treatments, improves transfer to real-world behavior change. The authors examined whether cognitive remediation effectively ...
https://doi.org/10.1176/appi.ajp.2012.11091337Publication date: 01 July 2012
Pages719–724Objective: Some 25%–30% of patients with schizophrenia have auditory verbal hallucinations that are refractory to antipsychotic drugs. Outcomes in studies of repetitive transcranial magnetic stimulation suggest the possibility that application of ...
https://doi.org/10.1176/appi.ajp.2012.11071091Publication date: 01 July 2012
Pages725–734Objective: Antidopaminergic drugs bind to hERG1 potassium channels encoded by the gene KCNH2, which accounts for the side effect of QT interval prolongation. KCNH2 has also been associated with schizophrenia risk, and risk alleles predict increased ...
https://doi.org/10.1176/appi.ajp.2012.11081214Publication date: 01 July 2012
Pages735–742When smokers were separated by their nicotinic receptor gene variants, those with the low-risk genotype responded equally well to pharmacological treatments, including both nicotine replacement and bupropion, and nonpharmacological therapies. Those with ...
https://doi.org/10.1176/appi.ajp.2012.11101545Publication date: 01 July 2012
Pages743–749Objective: Psychopathy is a personality disorder associated with severely antisocial behavior and a host of cognitive and affective deficits. The neuropathological basis of the disorder has not been clearly established. Cortical thickness is a sensitive ...
https://doi.org/10.1176/appi.ajp.2012.11111627Publication date: 01 July 2012
Pages750–758Objective: Amygdala dysfunction has been reported to exist in youths and adults with psychopathic traits. However, there has been disagreement as to whether this dysfunction reflects a primary emotional deficit or is secondary to atypical attentional ...
https://doi.org/10.1176/appi.ajp.2012.11081270