American Journal of Psychiatry
- Volume 169
- Number 8
- August 2012
In This Issue
Perspectives
Editorial
Perspectives
Images in Psychiatry
Perspectives
Education in Psychiatry
Publication date: 01 August 2012
Pages785–789The authors quantified, first, the effect of misclassified controls (i.e., individuals who are affected with the disease under study but who are classified as controls) on the ability of a case-control study to detect an association between a disease and ...
https://doi.org/10.1176/appi.ajp.2012.11111686Perspectives
Reviews and Overviews
Publication date: 01 August 2012
Pages790–804Objective: Collaborative chronic care models (CCMs) improve outcome in chronic medical illnesses and depression treated in primary care settings. The effect of such models across other treatment settings and mental health conditions has not been ...
https://doi.org/10.1176/appi.ajp.2012.11111616New Research
Articles
Publication date: 01 August 2012
Pages805–812N-acetylcysteine (1,200 mg twice a day) was added to contingency management intervention and very brief weekly cessation counseling in an 8-week, double-blind, randomized, placebo-controlled trial for treatment-seeking cannabis-dependent adolescents. The ...
https://doi.org/10.1176/appi.ajp.2012.12010055Publication date: 01 August 2012
Pages813–821Women who experienced amenorrhea during their first antipsychotic treatment for schizophrenia also received metformin, 1000 mg/day, for 6 months in a double-blind placebo-controlled study. Two-thirds of metformin-treated patients, compared to 5% of ...
https://doi.org/10.1176/appi.ajp.2012.11091432Publication date: 01 August 2012
Pages822–830Objective: Poor prenatal nutrition has been associated with schizophrenia spectrum disorders in the Netherlands and China, and it has been suggested that perinatal and postnatal nutritional factors lead to the development of schizophrenia and the ...
https://doi.org/10.1176/appi.ajp.2012.11081173Publication date: 01 August 2012
Pages831–840Objective: Although the amygdala and ventrolateral prefrontal cortex have been implicated in the pathophysiology of bipolar I disorder, the neural mechanisms underlying bipolar II disorder remain unknown. The authors examined neural activity in response to ...
https://doi.org/10.1176/appi.ajp.2012.11030349Publication date: 01 August 2012
Pages841–850Objective: Increased amygdala response to negative emotions seen in functional MRI (fMRI) has been proposed as a biomarker for negative emotion processing bias underlying depressive symptoms and vulnerability to depressive relapse that are normalized by ...
https://doi.org/10.1176/appi.ajp.2012.11121774Publication date: 01 August 2012
Pages851–859Background: Modulation of nicotinic acetylcholine receptors (nAChRs), specifically those containing the β2 subunit, may be effective in treating patients with major depressive disorder. Using [123I]5-I-A-85380 single photon emission computed tomography (...
https://doi.org/10.1176/appi.ajp.2012.11101546Publication date: 01 August 2012
Pages860–866Severe Tourette's syndrome that cannot be managed with medication is now being experimentally treated with deep brain stimulation. Ten of 11 patients in a series reported 48% reduction in motor tics and 56% reduction in phonic tics. Effects were sustained ...
https://doi.org/10.1176/appi.ajp.2012.11101583