American Journal of Psychiatry

Objective:Women with a history of bipolar disorder, postpartum psychosis, or both are at high risk for postpartum relapse. The aim of this meta-analysis was to estimate the risk of postpartum relapse in these three patient groups.Method:A systematic ...

https://doi.org/10.1176/appi.ajp.2015.15010124

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SAVE ARTICLE

The Sequential Integration of Pharmacotherapy and Psychotherapy in the Treatment of Major Depressive Disorder: A Meta-Analysis of the Sequential Model and a Critical Review of the Literature

Publication date: 20 October 2015

Pages128–137

Objective:A number of randomized controlled trials in major depressive disorder have employed a sequential model, which consists of the use of pharmacotherapy in the acute phase and of psychotherapy in its residual phase. The aim of this review was to ...

https://doi.org/10.1176/appi.ajp.2015.15040476

Articles

Defense Mechanisms of Pregnant Mothers Predict Attachment Security, Social-Emotional Competence, and Behavior Problems in Their Toddlers

Publication date: 11 September 2015

Pages138–146

Objective:For at-risk (single parent, low income, low support) mothers, healthy adaptation and the ability to manage stress have clear implications for parenting and the social-emotional well-being of their young offspring. The purpose of this ...

https://doi.org/10.1176/appi.ajp.2015.15020173

The Roles of Maternal Depression, Serotonin Reuptake Inhibitor Treatment, and Concomitant Benzodiazepine Use on Infant Neurobehavioral Functioning Over the First Postnatal Month

Publication date: 30 October 2015

Pages147–157

Objective:The purpose of this article was to systematically compare the developmental trajectory of neurobehavior over the first postnatal month for infants with prenatal exposure to pharmacologically untreated maternal depression, selective serotonin ...

https://doi.org/10.1176/appi.ajp.2015.14080989

Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression

Publication date: 04 September 2015

Pages158–165

Objective:The authors investigated the relative importance of genetic and environmental influences on perinatal depression, and the genetic overlap between perinatal depression and nonperinatal depression.Method:Analyses were conducted using structural ...

https://doi.org/10.1176/appi.ajp.2015.15010085

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Comparative Effectiveness of Clozapine and Standard Antipsychotic Treatment in Adults With Schizophrenia

Publication date: 06 November 2015

Pages166–173

Objective:The authors compared the effectiveness of initiating treatment with either clozapine or a standard antipsychotic among adults with evidence of treatment-resistant schizophrenia in routine clinical practice.Method:U.S. national Medicaid data from ...

https://doi.org/10.1176/appi.ajp.2015.15030332

Video

Systematic Review and Meta-Analysis: Dose-Response Relationship of Selective Serotonin Reuptake Inhibitors in Major Depressive Disorder

Publication date: 10 November 2015

Pages174–183

Objective:Previous studies suggested that the treatment response to selective serotonin reuptake inhibitors (SSRIs) in major depressive disorder follows a flat response curve within the therapeutic dose range. The present study was designed to clarify the ...

https://doi.org/10.1176/appi.ajp.2015.15030331

Longitudinal Psychiatric Symptoms in Prodromal Huntington’s Disease: A Decade of Data

Publication date: 16 October 2015

Pages184–192

Objective:Psychiatric symptoms are a significant aspect of Huntington’s disease, an inherited neurodegenerative illness. The presentation of these symptoms is highly variable, and their course does not fully correlate with motor or cognitive disease ...

https://doi.org/10.1176/appi.ajp.2015.14121551