American Journal of Psychiatry
- Volume 173
- Number 7
- July 2016
Editorials
Treatment in Psychiatry
Images in Psychiatry
APA Presidential Addresses
Reviews and Overviews
Messages for Clinicians: Moderators and Mediators of Treatment Outcome in Randomized Clinical Trials
Publication date: 17 March 2016
Pages672–679Many problems in randomized clinical trial design, execution, analysis, presentation and interpretation stem in part from an inadequate understanding of the roles of moderators and mediators of treatment outcome. As a result, 1) the results of clinical ...
https://doi.org/10.1176/appi.ajp.2016.15101333Articles
Publication date: 01 April 2016
Pages680–687Objective: Interpersonal psychotherapy (IPT) has been developed for the treatment of depression but has been examined for several other mental disorders. A comprehensive meta-analysis of all randomized trials examining the effects of IPT for all mental ...
https://doi.org/10.1176/appi.ajp.2015.15091141Publication date: 12 February 2016
Pages688–694Objective: The purpose of this study was to determine the cumulative rates of 2- and 4-year remission, and the recurrences that follow them, of 24 symptoms of borderline personality disorder over 16 years of prospective follow-up. Method: A total of 290 ...
https://doi.org/10.1176/appi.ajp.2015.15081045Publication date: 19 February 2016
Pages695–704Objective: The authors sought to assess dimensional symptomatic predictors of new-onset bipolar spectrum disorders in youths at familial risk of bipolar disorder (“at-risk” youths). Method: Offspring 6–18 years old of parents with bipolar I or II disorder (N=...
https://doi.org/10.1176/appi.ajp.2015.15040414Publication date: 25 March 2016
Pages705–713Objective: Increased risk of psychopathology is observed in children exposed to maternal prenatal distress, and elevated maternal cortisol and epigenetic regulation of placental glucocorticoid-pathway genes are potential mechanisms. The authors examined ...
https://doi.org/10.1176/appi.ajp.2015.15091171Publication date: 19 February 2016
Pages714–721Objective: Phosphodiesterase 10A (PDE10A) is an enzyme present in striatal medium spiny neurons that degrades the intracellular second messengers triggered by dopamine signaling. The pharmaceutical industry has considerable interest in PDE10A inhibitors ...
https://doi.org/10.1176/appi.ajp.2015.15040518Publication date: 19 February 2016
Pages722–730Objective: Bipolar disorder and disruptive mood dysregulation disorder (DMDD) are clinically and pathophysiologically distinct, yet irritability can be a clinical feature of both illnesses. The authors examine whether the neural mechanisms mediating ...
https://doi.org/10.1176/appi.ajp.2015.15060833Letters to the Editor
Book Forum
APA Official Actions
Publication date: 01 July 2016
Pages740–750The following are edited/abbreviated versions of the annual reports of the APA Secretary, Treasurer, CEO and Medical Director, Speaker, and Speaker-Elect and the chairpersons of the APA Committee on Bylaws, Membership Committee, Committee of Tellers, and ...
https://doi.org/10.1176/appi.ajp.2015.173701Correction
Past Issues
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Vol. 181 | No. 11
Vol. 181 | No. 10
Vol. 181 | No. 9
