American Journal of Psychiatry
- Volume 175
- Number 5
- May 2018
Editorials
Clinical Case Conference
Perspectives in Global Mental Health
Images in Psychiatry
Reviews and Overviews
Publication date: 24 January 2018
Pages411–426Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and usually has its onset during youth. Its chronic course is associated with high rates of morbidity and mortality, making bipolar disorder one of the main causes ...
https://doi.org/10.1176/appi.ajp.2017.17090972Articles
Publication date: 12 January 2018
Pages427–433Objective:The authors assessed the efficacy of trauma memory reactivation performed under the influence of propranolol, a noradrenergic beta-receptor blocker, as a putative reconsolidation blocker, in reducing symptoms of posttraumatic stress disorder (...
https://doi.org/10.1176/appi.ajp.2017.17050481Publication date: 24 January 2018
Pages434–442Objective:The authors sought to describe patterns of health care use prior to first diagnosis of a psychotic disorder in a population-based sample.Method:Electronic health records and insurance claims from five large integrated health systems were used to ...
https://doi.org/10.1176/appi.ajp.2017.17080844Publication date: 02 March 2018
Pages443–452Objective:Early psychosis intervention (EPI) programs improve clinical and functional outcomes for people with first-episode psychosis. Less is known about the impact of these programs on the larger health care system. The authors sought to compare ...
https://doi.org/10.1176/appi.ajp.2017.17050480Publication date: 15 December 2017
Pages453–462Objective:Brain imaging studies of structural abnormalities in OCD have yielded inconsistent results, partly because of limited statistical power, clinical heterogeneity, and methodological differences. The authors conducted meta- and mega-analyses ...
https://doi.org/10.1176/appi.ajp.2017.17050485Publication date: 12 January 2018
Pages463–470Objective:The antidepressant escitalopram is predominantly metabolized by the polymorphic CYP2C19 enzyme. The authors investigated the effect of CYP2C19 genotype on exposure and therapeutic failure of escitalopram in a large patient population.Method:A ...
https://doi.org/10.1176/appi.ajp.2017.17050550Publication date: 02 March 2018
Pages471–479Objective:The authors sought to assess associations among early-life exposure to adversity, the development and maturation of neurons and brain circuits, and neurodevelopmental outcomes. Specifically, they examined whether fetal exposure to placental ...
https://doi.org/10.1176/appi.ajp.2017.16121433Letters to the Editor
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