American Journal of Psychiatry
- Volume 175
- Number 6
- June 2018
Editorials
Commentary
Treatment in Psychiatry
Images in Psychiatry
Reviews and Overviews
Publication date: 01 June 2018
Pages508–516Traumatic stressors have always been a part of the human experience. What is now referred to as posttraumatic stress disorder (PTSD) was first studied in the context of military trauma during the Civil War and World War I but most extensively in World War ...
https://doi.org/10.1176/appi.ajp.2017.17080955Articles
Publication date: 12 January 2018
Pages517–529Objective: DNA methylation has been proposed as an epigenetic mechanism by which early-life experiences become “embedded” in the genome and alter transcriptional processes to compromise health. The authors sought to investigate whether early-life ...
https://doi.org/10.1176/appi.ajp.2017.17060693Publication date: 12 January 2018
Pages530–537Objective: To understand the role of depressive symptoms in preclinical Alzheimer’s disease, it is essential to define their temporal relationship to Alzheimer’s proteinopathies in cognitively normal older adults. The study objective was to examine ...
https://doi.org/10.1176/appi.ajp.2017.17040442Publication date: 28 November 2017
Pages538–544Objective: This study analyzed health service patterns before opioid-related death among nonelderly individuals in the Medicaid program, focusing on decedents with and without past-year diagnoses of noncancer chronic pain. Methods: The authors identified ...
https://doi.org/10.1176/appi.ajp.2017.17070808Publication date: 02 March 2018
Pages545–554Objective: The extent to which major depression is the outcome of a single biological mechanism or represents a final common pathway of multiple disease processes remains uncertain. Genetic approaches can potentially identify etiologic heterogeneity in ...
https://doi.org/10.1176/appi.ajp.2017.17060621Publication date: 02 March 2018
Pages555–563Objective: Alzheimer’s disease is a heritable neurodegenerative disorder in which early-life precursors may manifest in cognition and brain structure. The authors evaluate this possibility by examining, in youths, associations among polygenic risk score ...
https://doi.org/10.1176/appi.ajp.2017.17050529Publication date: 07 May 2018
Pages564–574Objective: Some atypical antipsychotics are associated with metabolic side effects, which are risk factors for gestational diabetes. The authors examined the risk of developing gestational diabetes associated with the continuation of treatment with ...
https://doi.org/10.1176/appi.ajp.2018.17040393