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Focus

  • Volume 14
  • Number 4
  • October 2016

From the Guest Editor

Reviews

Publication date: 01 October 2016

Pages410–421

Mild traumatic brain injury (MTBI) is a significant public health problem worldwide. Injured individuals have an increased relative risk of developing a variety of neuropsychiatric conditions associated with the profile of brain regions typically affected ...

https://doi.org/10.1176/appi.focus.20160025

Publication date: 01 October 2016

Pages422–431

Psychogenic nonepileptic seizures (PNES) are a subtype of conversion disorder (also called functional neurological symptom disorder in DSM-5). Patients with PNES are high utilizers of health care and can have disability levels similar to those of patients ...

https://doi.org/10.1176/appi.focus.20160020

Publication date: 01 October 2016

Pages432–436

Antibodies to brain cell-surface proteins have recently been identified in patients whose symptoms cross the boundary between neurology and psychiatry and are associated with syndromes that are responsive to treatment with immunosuppression-based ...

https://doi.org/10.1176/appi.focus.20160019

Clinical Synthesis

Publication date: 01 October 2016

Pages437–447

Cognitive impairment is ubiquitous in medicine and a common experience in everyday life. When severe, persistent, or progressive, it becomes a matter of clinical concern. Top causes of clinically significant cognitive impairment are neurodegenerative ...

https://doi.org/10.1176/appi.focus.20160026

Publication date: 01 October 2016

Pages448–464

The term frontotemporal dementia (FTD) describes a diverse group of clinical syndromes, including behavioral-variant FTD (bvFTD), nonfluent/agrammatic-variant primary progressive aphasia (nfvPPA), semantic-variant primary progressive aphasia (svPPA), FTD ...

https://doi.org/10.1176/appi.focus.20160018

Publication date: 01 October 2016

Pages465–472

Mood disorders associated with epilepsy are very common and overrepresented compared with other chronic medical conditions. Depression is a particularly common and worrisome comorbidity, especially because suicidality seems to be increased significantly ...

https://doi.org/10.1176/appi.focus.20160017

Ask the Expert

Ethics Commentary

Communication Commentary

Patient Management Exercise

Bibliography

Abstracts

Influential Publications

Publication date: 01 October 2016

Pages492–498

Worldwide prevalence of dementia is predicted to double every 20 years. The most common cause in individuals over 65 is Alzheimer’s disease (AD), but in those under 65, frontotemporal dementia (FTD) is as frequent. The physical and cognitive decline that ...

https://doi.org/10.1176/appi.focus.140406

Publication date: 01 October 2016

Pages499–509

Adaptive behavior requires neural systems that mediate the evaluation of stimuli in terms of the well-being of the organism and generate subsequent goal-directed behavior. The authors provide an overview of these systems, with an emphasis on those related ...

https://doi.org/10.1176/appi.focus.140401

Publication date: 01 October 2016

Pages510–515

Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a recently-discovered synaptic autoimmune disorder in which auto-antibodies target NMDARs in the brain, leading to their removal from the synapse. Patients manifest with prominent psychiatric ...

https://doi.org/10.1176/appi.focus.140405

Publication date: 01 October 2016

Pages516–522

The aim of this study was to investigate the neuropsychological correlates of behavioral and psychological symptoms (BPSD) in patients affected by various forms of dementia, namely Alzheimer’s disease (AD), frontal-variant frontotemporal dementia (fvFTD), ...

https://doi.org/10.1176/appi.focus.140407

Publication date: 01 October 2016

Pages523–532

This review presents data showing that apathy is common across a number of disorders. Apathy is not only common, but is also associated with significant problems: reduced functional level, decreased response to treatment, poor illness outcome, caregiver ...

https://doi.org/10.1176/appi.focus.140402

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