The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 15
- Number 3
- August 2003
Windows to the Brain
Special Article
Publication date: 01 August 2003
Pages294–305There has been much interest in the role of serotonin in aggressive behavior during the past two decades, but no simple one-to-one causal relationship has been found between this biological variable and aggression. The influence of serotonin is best ...
https://doi.org/10.1176/jnp.15.3.294Publication date: 01 August 2003
Pages306–316The dopamine (DA) system has long been associated with the pathophysiology of psychosis. The DA theory of schizophrenia continues to find support in neuroreceptor imaging and ligand-binding studies that show excess DA transmission in patients, as compared ...
https://doi.org/10.1176/jnp.15.3.306Regular Article
Publication date: 01 August 2003
Pages317–325Methamphetamine use is on the rise, with an imminent upsurge of abuse and dependence reported across the United States. Currently, preliminary evidence suggests that methamphetamine dependence may cause long-term neural damage in humans, with concomitant ...
https://doi.org/10.1176/jnp.15.3.317Publication date: 01 August 2003
Pages326–332This study examined brain functioning in patients with Lyme encephalopathy. Eleven patients underwent neuropsychological tests and Xenon133-regional cerebral blood flow (rCBF) studies, using an external detector system. Each rCBF scan was age- and sex-...
https://doi.org/10.1176/jnp.15.3.326Publication date: 01 August 2003
Pages333–339Cognitive reserve (CR) theory proposes that certain genetic and nonacquired variables, such as larger head size and greater neuronal density, and some life experiences, such as higher educational and occupational attainment, provide a buffer against brain ...
https://doi.org/10.1176/jnp.15.3.333Publication date: 01 August 2003
Pages340–345A population-based prevalence sample of 355 residents of Cache County, Utah, who were diagnosed with dementia, was rated on the Neuropsychiatric Inventory (NPI). Of the 355 residents, 119 had no neuropsychiatric symptoms at baseline and were, consequently,...
https://doi.org/10.1176/jnp.15.3.340Publication date: 01 August 2003
Pages346–353This cross-sectional study examines relationships among the constellation of psychiatric syndromes in Alzheimer's disease (AD) as a function of dementia severity in 1155 patients with probable AD. The frequency of major depression decreased in severe ...
https://doi.org/10.1176/jnp.15.3.346Publication date: 01 August 2003
Pages354–358To investigate a possible effect of the apolipoprotein (APOE) ϵ4 allele on memory decline in Alzheimer's disease (AD), we examined 64 AD patients with the APOE ϵ3/3, ϵ3/4, or ϵ4/4 allele using the Alzheimer Disease Assessment Scale-Cognitive subscale (...
https://doi.org/10.1176/jnp.15.3.354Publication date: 01 August 2003
Pages359–362This study compared the performances of matched schizophrenia patients with or without obsessive-compulsive (OC) symptoms, patients with obsessive-compulsive disorder (OCD), and control subjects on selected frontal lobe tests. Schizophrenic patients ...
https://doi.org/10.1176/jnp.15.3.359Publication date: 01 August 2003
Pages363–366Delirium is a common syndrome among hospitalized elderly patients. In humans, sleep and circadian rhythms are disturbed during delirium, and both are influenced by the hormone melatonin. This prompted us to investigate the relationship of the clinical ...
https://doi.org/10.1176/jnp.15.3.363Clinical and Research Reports
Publication date: 01 August 2003
Pages367–370Proton magnetic resonance spectroscopy was used to compare medial temporal lobe (MTL) concentrations of N-acetylaspartate and choline between former prisoners of war (POWs) with and without posttraumatic stress disorder (PTSD). MTL N-acetylaspartate and ...
https://doi.org/10.1176/jnp.15.3.367Publication date: 01 August 2003
Pages371–374This study evaluated the frequency of obsessive-compulsive disorder (OCD), obsessive-compulsive symptoms (OCS), and related disorders (e.g., tic disorders, trichotillomania, and body dysmorphic disorder) in 100 patients with Parkinson's disease (PD) and ...
https://doi.org/10.1176/jnp.15.3.371Publication date: 01 August 2003
Pages375–377This study investigated the effectiveness and tolerability of a switching strategy using quetiapine in 16 women with schizophrenia who were suffering from haloperidol- or risperidone-induced amenorrhea. Findings revealed that 10 patients (71.6%) resumed ...
https://doi.org/10.1176/jnp.15.3.375Publication date: 01 August 2003
Pages378–380A rare disorder, neuroacanthocytosis is characterized by chorea, tics, subcortical cognitive impairments, and acanthocytosis. This study presents two men with neuroacanthocytosis who were initially diagnosed with schizophrenia. Findings revealed the ...
https://doi.org/10.1176/jnp.15.3.378Book Reviews
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