American Journal of Psychiatry
- Volume 168
- Number 7
- July 2011
In This Issue
Perspectives
Editorials
Perspectives
Commentary
Perspectives
Clinical Case Conference
Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 July 2011
Pages681–688Objective: The authors systematically reviewed the management of treatment-refractory depression in older people (defined as age 55 or older). Method: The authors conducted an electronic database search and reviewed the 14 articles that fit predetermined ...
https://doi.org/10.1176/appi.ajp.2011.10081165New Research
Articles
Publication date: 01 July 2011
Pages689–701Objective: Two antidepressant medication combinations were compared with selective serotonin reuptake inhibitor monotherapy to determine whether either combination produced a higher remission rate in first-step acute-phase (12 weeks) and long-term (7 ...
https://doi.org/10.1176/appi.ajp.2011.10111645Publication date: 01 July 2011
Pages702–708Objective: This randomized trial addressed the risks and benefits of staying on antipsychotic polypharmacy or switching to monotherapy. Method: Adult outpatients with schizophrenia taking two antipsychotics (127 participants across 19 sites) were randomly ...
https://doi.org/10.1176/appi.ajp.2011.10060908Publication date: 01 July 2011
Pages709–717Objective: Naltrexone, an efficacious medication for alcohol dependence, does not work for everyone. Symptoms such as insomnia and mood instability that are most evident during early abstinence might respond better to a different pharmacotherapy. ...
https://doi.org/10.1176/appi.ajp.2011.10101436Publication date: 01 July 2011
Pages718–726Objective: Obsessive-compulsive disorder (OCD) is characterized by repetitive, ritualistic behaviors and thought patterns. Although patients with OCD report that these compulsive behaviors are unproductive and often senseless, they are unable to desist. ...
https://doi.org/10.1176/appi.ajp.2011.10071062Publication date: 01 July 2011
Pages727–734Objective: Clinical and preclinical evidence suggests a hyperactive glutamatergic system in clinical depression. Recently, the metabotropic glutamate receptor 5 (mGluR5) has been proposed as an attractive target for novel therapeutic approaches to ...
https://doi.org/10.1176/appi.ajp.2011.09111607Publication date: 01 July 2011
Pages735–741Objective: Biased processing of emotion stimuli is thought to confer vulnerability to psychopathology, but few longitudinal studies of this link have been conducted. The authors examined the relationship between predeployment gaze bias for emotion stimuli ...
https://doi.org/10.1176/appi.ajp.2011.10091309Publication date: 01 July 2011
Pages742–748Objective: The authors examined treatment utilization and outcomes over 2 years among patients admitted to emergency departments with early-phase primary or substance-induced psychosis. The main hypothesis was that patients with substance-induced psychosis ...
https://doi.org/10.1176/appi.ajp.2011.10071051