American Journal of Psychiatry
- Volume 168
- Number 8
- August 2011
In This Issue
Perspectives
Editorials
Perspectives
Commentary
Perspectives
Introspection
Perspectives
Clinical Case Conference
Perspectives
Images in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 August 2011
Pages783–789Studies by Breen et al. and Pergadia et al. find evidence for genetic linkage between major depressive disorder and the same region on chromosome 3. The linked region contains the gene GRM7, which encodes a protein for the metabotropic glutamate receptor ...
https://doi.org/10.1176/appi.ajp.2011.11060835Publication date: 01 August 2011
Pages790–799Objective: Computer-assisted therapies offer a novel, cost-effective strategy for providing evidence-based therapies to a broad range of individuals with psychiatric disorders. However, the extent to which the growing body of randomized trials evaluating ...
https://doi.org/10.1176/appi.ajp.2011.10101443New Research
Articles
Publication date: 01 August 2011
Pages800–805Objective: A major focus of early intervention research is determining the risk of conversion to psychosis and developing optimal algorithms of prediction. Although reported rates of nonconversion vary in the literature, the nonconversion rate always ...
https://doi.org/10.1176/appi.ajp.2011.10081191Publication date: 01 August 2011
Pages806–813Objective: Cognitive deficits have been well documented in schizophrenia and have been shown to impair quality of life and to compromise everyday functioning. Recent studies of adolescents and young adults at high risk for developing psychosis show that ...
https://doi.org/10.1176/appi.ajp.2011.10081209Publication date: 01 August 2011
Pages814–821Objective: Several studies based on clinical samples have found an association between Toxoplasma gondii infection and schizophrenia, and a case-control study among U.S. military personnel with specimens available from both before and after diagnosis found ...
https://doi.org/10.1176/appi.ajp.2011.10091351Publication date: 01 August 2011
Pages822–830Objective: Longitudinal changes in gray matter volume and cognitive performance were evaluated among individuals exposed to neurotropic herpes simplex virus subtype 1 (HSV1). There is a replicable association of HSV1 exposure with smaller prefrontal ...
https://doi.org/10.1176/appi.ajp.2011.10101423Publication date: 01 August 2011
Pages831–839Objective: The impact of the atypical antipsychotics olanzapine, quetiapine, and risperidone on cognition in patients with Alzheimer's disease is unclear. The authors assessed the effects of time and treatment on neuropsychological functioning during the ...
https://doi.org/10.1176/appi.ajp.2011.08121844Publication date: 01 August 2011
Pages840–847Objective: The purpose of this study was to find loci for major depression via linkage analysis of a large sibling pair sample. Method: The authors conducted a genome-wide linkage analysis of 839 families consisting of 971 affected sibling pairs with severe ...
https://doi.org/10.1176/appi.ajp.2011.10091342Publication date: 01 August 2011
Pages848–852Objective: The authors tested for genetic linkage of DSM-IV-diagnosed major depressive disorder in families that were ascertained for cigarette smoking. Method: Within a study that targeted families characterized by a history of smoking, analyses derived a ...
https://doi.org/10.1176/appi.ajp.2011.10091319