American Journal of Psychiatry
- Volume 174
- Number 11
- November 2017
Editorials
Treatment in Psychiatry
Perspectives in Global Mental Health
Articles
Publication date: 28 July 2017
Pages1054–1063Objective: Chromosome 22q11.2 deletion syndrome (22q11.2DS) is associated with a more than 20-fold increased risk for developing schizophrenia. The aim of this study was to identify additional genetic factors (i.e., “second hits”) that may contribute to ...
https://doi.org/10.1176/appi.ajp.2017.16121417Publication date: 04 August 2017
Pages1064–1074Objective: Kraepelin considered declining course a hallmark of schizophrenia, but others have suggested that outcomes usually stabilize or improve after treatment initiation. The authors investigated this question in an epidemiologically defined cohort ...
https://doi.org/10.1176/appi.ajp.2017.16101191Publication date: 16 December 2016
Pages1075–1085Objective: Social impairment is a long-recognized core feature of schizophrenia and is common in other psychotic disorders. Still, to date the long-term trajectories of social impairment in psychotic disorders have rarely been studied systematically. ...
https://doi.org/10.1176/appi.ajp.2016.15111419Publication date: 04 August 2017
Pages1086–1093Objective: Clinicians treating older patients with bipolar disorder with mood stabilizers need evidence from age-specific randomized controlled trials. The authors describe findings from a first such study of late-life mania. Method: The authors compared the ...
https://doi.org/10.1176/appi.ajp.2017.15050657Publication date: 04 August 2017
Pages1094–1101Objective: Although several risk factors have been identified for alcohol use disorder, many individuals with these factors do not go on to develop the disorder. Identifying early phenotypic differences between vulnerable individuals and healthy control ...
https://doi.org/10.1176/appi.ajp.2017.16101180Publication date: 15 September 2017
Pages1102–1111Objective: The striatum receives segregated and integrative white matter tracts from the cortex facilitating information processing in the cortico-basal ganglia network. The authors examined both types of input tracts in the striatal associative loop in ...
https://doi.org/10.1176/appi.ajp.2017.16091046Publication date: 26 September 2017
Pages1112–1119Objective: Previous studies have implicated aberrant reward processing in the pathogenesis of adolescent depression. However, no study has used functional connectivity within a distributed reward network, assessed using resting-state functional MRI (fMRI), ...
https://doi.org/10.1176/appi.ajp.2017.17040430Letters to the Editor
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