American Journal of Psychiatry

A large body of evidence has demonstrated that exposure to childhood maltreatment at any stage of development can have long-lasting consequences. It is associated with a marked increase in risk for psychiatric and ...

https://doi.org/10.1176/appi.ajp.2019.19010020

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Association of Childhood Maltreatment With Interpersonal Distance and Social Touch Preferences in Adulthood

Publication date: 16 August 2019

Pages37–46

Objective: Childhood maltreatment is a major risk factor for psychopathology associated with interpersonal problems in adulthood, but the etiological pathways involved are still unclear. The authors propose that childhood maltreatment confers risk for ...

https://doi.org/10.1176/appi.ajp.2019.19020212

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Adverse Childhood Experiences: Implications for Offspring Telomere Length and Psychopathology

Publication date: 06 September 2019

Pages47–57

Objective: Adverse childhood experiences (ACEs) are associated with mental and physical health risks that, through biological and psychosocial pathways, likely span generations. Within an individual, telomere length (TL), an established marker of cellular ...

https://doi.org/10.1176/appi.ajp.2019.18030335

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Association of Prospective Risk for Chronic PTSD Symptoms With Low TNFα and IFNγ Concentrations in the Immediate Aftermath of Trauma Exposure

Publication date: 29 July 2019

Pages58–65

Objective: Although several reports have documented heightened systemic inflammation in posttraumatic stress disorder (PTSD), few studies have assessed whether inflammatory markers serve as prospective biomarkers for PTSD risk. The present study aimed to ...

https://doi.org/10.1176/appi.ajp.2019.19010039

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Maternal Bacterial Infection During Pregnancy and Offspring Risk of Psychotic Disorders: Variation by Severity of Infection and Offspring Sex

Publication date: 04 October 2019

Pages66–75

Objective: Previous studies suggest that prenatal immune challenges may elevate the risk of schizophrenia and related psychoses in offspring, yet there has been limited research focused on maternal bacterial infection. The authors hypothesized that ...

https://doi.org/10.1176/appi.ajp.2019.18101206

Lithium Exposure During Pregnancy and the Postpartum Period: A Systematic Review and Meta-Analysis of Safety and Efficacy Outcomes

Publication date: 18 October 2019

Pages76–92

Objective: Uncertainty surrounds the risks of lithium use during pregnancy in women with bipolar disorder. The authors sought to provide a critical appraisal of the evidence related to the efficacy and safety of lithium treatment during the peripartum ...

https://doi.org/10.1176/appi.ajp.2019.19030228