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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 10
  • Number 4
  • November 1998

Special Article

Publication date: 01 November 1998

Pages373–382

Alzheimer's disease is the leading cause of mental impairment in elderly people, accounting for a large proportion of admissions to nursing homes and assisted living homes. Psychiatric symptoms associated with Alzheimer's disease, although common, have ...

https://doi.org/10.1176/jnp.10.4.373

Publication date: 01 November 1998

Pages383–394

For many years, the structures of the medial temporal lobe have been implicated in the pathogenesis of schizophrenia. Recent hypotheses, based on data from MRI and functional imaging, propose that disruption of frontotemporal neural networks may be an ...

https://doi.org/10.1176/jnp.10.4.383

Publication date: 01 November 1998

Pages395–404

Of the proliferating approaches to neuropsychiatric assessment, a relatively neglected technique is the venerable, accessible, noninvasive, and inexpensive neurologic examination. This article organizes and synthesizes the literature on neurological ...

https://doi.org/10.1176/jnp.10.4.395

Regular Article

Publication date: 01 November 1998

Pages405–412

The authors assessed the accuracy of published clinical criteria and their own modifications of those criteria in diagnosing Lewy body disease (LBD). Clinical diagnoses were made by two clinicians, blinded to neuropathologic diagnoses, using the Rochester ...

https://doi.org/10.1176/jnp.10.4.405

Publication date: 01 November 1998

Pages413–420

The amygdala is thought to be an important neural structure underlying the “fight-or-flight” response, but information on its role in humans is scarce. The clinical and psychophysiological effects of amygdalar destruction were studied in 2 patients who ...

https://doi.org/10.1176/jnp.10.4.413

Publication date: 01 November 1998

Pages421–425

The authors assessed a consecutive series of 196 patients with probable Alzheimer's disease (AD) for the presence of aggressive behavior, using a standardized neurological, neuropsychiatric, and neuropsychological battery that included both the Overt ...

https://doi.org/10.1176/jnp.10.4.421

Publication date: 01 November 1998

Pages426–432

Relationships between measures of executive skills and neuropsychiatric and functional status were examined in a group of 31 patients with Alzheimer's disease. Deficits in four executive skills tests were significantly associated with the Agitation/...

https://doi.org/10.1176/jnp.10.4.426

Publication date: 01 November 1998

Pages433–439

The authors examined 65 patients with Alzheimer's disease for delusions and explored the relationship of delusions with regional cerebral glucose metabolism determined by [18F]fluorodeoxyglucose PET. In patients with delusions (n=26), normalized glucose ...

https://doi.org/10.1176/jnp.10.4.433

Publication date: 01 November 1998

Pages440–447

Patients with clinical diagnoses of Alzheimer's disease, vascular dementia, or undifferentiated dementia were rated on standardized measures of depression, cognitive impairment, and functional impairment. Logistic regression was used to evaluate the ...

https://doi.org/10.1176/jnp.10.4.440

Publication date: 01 November 1998

Pages448–452

A sample of 44 patients with a neurological disorder and a DSM-IV diagnosis of Psychosis due to a General Medical Condition were followed on average for 4 years and their response to treatment and clinical course noted. Outcome was more benign than in ...

https://doi.org/10.1176/jnp.10.4.448

Clinical and Research Report

Publication date: 01 November 1998

Pages453–455

Emotional incontinence (EI) is a perturbing condition characterized by uncontrollable outbursts of exaggerated, involuntary facial expressions and pathological crying or laughter. There is increasing evidence that serotonergic neurotransmission may be ...

https://doi.org/10.1176/jnp.10.4.453

Publication date: 01 November 1998

Pages456–458

Three patients with neuropathologically confirmed frontotemporal dementia, motor neuron disease type, manifested hallucinations. In this dementia, the superficial layers of the frontal and temporal cortices are predominantly affected. Hallucinations may ...

https://doi.org/10.1176/jnp.10.4.456

Neuropsychiatric Practice and Opinion

Book Review

Letter

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