American Journal of Psychiatry
- Volume 157
- Number 3
- March 2000
Editorial
Images in Neuroscience
Special Article
Publication date: 01 March 2000
Pages327–337OBJECTIVE: Recent reports have criticized the design of antidepressant studies and have questioned their validity. These critics have concluded that antidepressants are no better than placebo treatment and that their illusory superiority depends on ...
https://doi.org/10.1176/appi.ajp.157.3.327Regular Article
Publication date: 01 March 2000
Pages338–343OBJECTIVE: Many claims have been made for superior compliance with selective serotonin reuptake inhibitors (SSRIs) compared with tricyclic antidepressants, but to date meta-analyses have not confirmed reduced dropouts in randomized controlled trials. The ...
https://doi.org/10.1176/appi.ajp.157.3.338Publication date: 01 March 2000
Pages344–350OBJECTIVE: The atypical subtype of depression appears to be both well validated and common. Although monoamine oxidase inhibitors are effective in treating atypical depression, their side effects and prescription-associated dietary restrictions reduce ...
https://doi.org/10.1176/appi.ajp.157.3.344Publication date: 01 March 2000
Pages351–359OBJECTIVE: This study compared nortriptyline and fluoxetine with placebo in the treatment of depression and in recovery from physical and cognitive impairments after stroke. METHOD: A total of 104 patients with acute stroke enrolled between 1991 and 1997 ...
https://doi.org/10.1176/appi.ajp.157.3.351Publication date: 01 March 2000
Pages360–367OBJECTIVE: The authors assessed changes over time in antidepressant utilization among elderly subjects regarding the prevalence of antidepressant users, shifts in prescription patterns, and related financial implications. METHOD: The authors conducted a ...
https://doi.org/10.1176/appi.ajp.157.3.360Publication date: 01 March 2000
Pages368–374OBJECTIVE: Case studies suggest cigarette abstinence may precipitate a major depressive episode. This study examined the incidence and predictors of major depression in the 12 months after treatment for smoking cessation. METHOD: Participants (N=304, 172 ...
https://doi.org/10.1176/appi.ajp.157.3.368Publication date: 01 March 2000
Pages375–379OBJECTIVE: Numerous studies have shown that the highest risk for first onset of depression occurs in women of childbearing years and that there is a strong association between lifetime rates of depressive disorders in mothers and their offspring. This ...
https://doi.org/10.1176/appi.ajp.157.3.375Publication date: 01 March 2000
Pages380–384OBJECTIVE: The authors’ goal was to examine the prevalence and experience of psychiatric morbidity among primary care patients with chronic fatigue in Hong Kong. METHOD: One hundred adult patients with medically unexplained fatigue for 6 or more months ...
https://doi.org/10.1176/appi.ajp.157.3.380Publication date: 01 March 2000
Pages385–392OBJECTIVE: Knowledge about the frequency, severity, and risk factors of somatization (somatic manifestations of psychological distress) among immigrants is limited. The authors examined somatic distress in an immigrant population in Israel, explored its ...
https://doi.org/10.1176/appi.ajp.157.3.385Publication date: 01 March 2000
Pages393–401OBJECTIVE: Lifetime rates of full and partial anorexia nervosa and bulimia nervosa were determined in first-degree relatives of diagnostically pure proband groups and relatives of matched, never-ill comparison subjects. METHOD: Rates of each eating ...
https://doi.org/10.1176/appi.ajp.157.3.393Publication date: 01 March 2000
Pages402–408OBJECTIVE: Schizophrenia is clinically heterogeneous. Recent linkage studies suggest that multiple genes are important in the etiology of schizophrenia. The authors examined the hypothesis of whether the clinical variability in schizophrenia is due to ...
https://doi.org/10.1176/appi.ajp.157.3.402Publication date: 01 March 2000
Pages409–415OBJECTIVE: Velocardiofacial syndrome is a common genetic condition often accompanied by mild cognitive impairment. Children and adolescents with velocardiofacial syndrome also are at greater risk for developing serious neuropsychiatric disorders in ...
https://doi.org/10.1176/appi.ajp.157.3.409Publication date: 01 March 2000
Pages416–421OBJECTIVE: The authors sought to investigate the contribution of genotype on structural brain abnormalities in schizophrenia. METHOD: Intracranial volumes and volumes of the cerebrum, white and gray matter, lateral and third ventricles, frontal lobes, ...
https://doi.org/10.1176/appi.ajp.157.3.416Publication date: 01 March 2000
Pages422–427OBJECTIVE: The inferior parietal lobule is a heteromodal association cortical region that has been implicated in the pathophysiology of schizophrenia. Inferior parietal lobule gray matter volumes have been shown to differ between healthy male and female ...
https://doi.org/10.1176/appi.ajp.157.3.422Publication date: 01 March 2000
Pages428–437OBJECTIVE: Few studies have evaluated the parietal lobe in schizophrenia despite the fact that it has an important role in attention, memory, and language—all functions that have been reported to be abnormal in schizophrenia. The inferior parietal lobule, ...
https://doi.org/10.1176/appi.ajp.157.3.428Publication date: 01 March 2000
Pages438–443OBJECTIVE: The authors’ goal was to investigate the suggestion of previous investigations that prenatal viral exposures might increase the later risk of psychotic disorders. METHOD: They conducted a follow-up study in young adulthood of a birth cohort ...
https://doi.org/10.1176/appi.ajp.157.3.438Clinical Case Conference
Images in Psychiatry
Brief Report
Publication date: 01 March 2000
Pages451–453OBJECTIVE: Childhood trauma has been associated with increased risk for both panic disorder and dissociative symptoms in adulthood. The authors hypothesized that among individuals with a primary diagnosis of panic disorder, those experiencing ...
https://doi.org/10.1176/appi.ajp.157.3.451Publication date: 01 March 2000
Pages454–456OBJECTIVE: Documentation of hypothalamic-pituitary-adrenal (HPA) axis disturbance in panic disorder has been inconsistent. Increased cortisol levels have been associated with altered HPA function due to stress. The authors examined salivary cortisol ...
https://doi.org/10.1176/appi.ajp.157.3.454Publication date: 01 March 2000
Pages457–459OBJECTIVE: This study compared dopamine D2 receptor binding potential in patients with social phobia and healthy comparison subjects. METHOD: Dopamine D2 receptor binding potential was assessed in 10 unmedicated subjects with generalized social phobia and ...
https://doi.org/10.1176/appi.ajp.157.3.457Publication date: 01 March 2000
Pages460–462OBJECTIVE: Cognitive functions of adolescents treated with ECT for mood disorder were evaluated at long-term follow-up. METHOD: At an average of 3.5 years (SD=1.7) after the last ECT, 10 subjects treated during adolescence with bilateral ECT for severe ...
https://doi.org/10.1176/appi.ajp.157.3.460Publication date: 01 March 2000
Pages463–465OBJECTIVE: Phenytoin, a classical anticonvulsant, shares with antimanic anticonvulsants the property of blockade of voltage-activated sodium channels. The authors therefore planned a trial of phenytoin for mania. METHOD: Patients with either bipolar I ...
https://doi.org/10.1176/appi.ajp.157.3.463Publication date: 01 March 2000
Pages466–468OBJECTIVE: The relationship between attention deficit hyperactivity disorder (ADHD) and earlier age at onset of affective illness was examined in probands with a history of bipolar disorder. METHOD: The authors assessed 56 adult bipolar subjects. Those ...
https://doi.org/10.1176/appi.ajp.157.3.466Publication date: 01 March 2000
Pages469–471OBJECTIVE: The authors sought to derive heritability estimates for anorexia nervosa and to explore the etiology of the comorbid relationship between anorexia nervosa and major depression. METHOD: They applied bivariate structural equation modeling to a ...
https://doi.org/10.1176/appi.ajp.157.3.469Publication date: 01 March 2000
Pages472–473OBJECTIVE: The authors assessed the growth of the literature on the topic of personality disorders before and after publication of DSM-III. METHOD: A MEDLINE search was conducted for journal articles concerning the personality disorders that were ...
https://doi.org/10.1176/appi.ajp.157.3.472Book Forum: NEUROPSYCHIATRY
Book Forum: PERSONALITY AND ITS DISORDERS
Book Forum: MANAGED CARE
Book Forum: PERSONALITY AND ITS DISORDERS
Book Forum: PSYCHOTHERAPY
Book Forum: PERSONALITY AND ITS DISORDERS
Letter to the Editor
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