American Journal of Psychiatry
- Volume 163
- Number 4
- April 2006
In This Issue
Editorial
Images in Neuroscience
Reviews and Overviews
Publication date: 01 April 2006
Pages579–585Objective: Stimulant medications, such as methylphenidate and amphetamines, are commonly prescribed to treat attention deficit hyperactivity disorder. Stimulant use increased fourfold from 1987 (0.6%) to 1996 (2.4%) among subjects 18-year-old ...
https://doi.org/10.1176/ajp.2006.163.4.579Treatment in Psychiatry
Clinical Case Conference
Images in Psychiatry
Article
Publication date: 01 April 2006
Pages600–610Objective: When a schizophrenia patient has an inadequate response to treatment with an antipsychotic drug, it is unclear what other antipsychotic to switch to and when to use clozapine. In this study, the authors compared switching to ...
https://doi.org/10.1176/ajp.2006.163.4.600Publication date: 01 April 2006
Pages611–622Background: In the treatment of schizophrenia, changing antipsychotics is common when one treatment is suboptimally effective, but the relative effectiveness of drugs used in this strategy is unknown. This randomized, double-blind study ...
https://doi.org/10.1176/ajp.2006.163.4.611Publication date: 01 April 2006
Pages623–629Objective: The purpose of the study was to assess the prevalence of DSM-IV dissociative disorders in an inner-city outpatient psychiatric population. Method: Subjects were 231 consecutive admissions (84 men and 147 women, ...
https://doi.org/10.1176/ajp.2006.163.4.623Publication date: 01 April 2006
Pages630–636Objective: Smaller hippocampal volume has been reported in several stress-related psychiatric disorders, including posttraumatic stress disorder (PTSD), borderline personality disorder with early abuse, and depression with early abuse. Patients ...
https://doi.org/10.1176/ajp.2006.163.4.630Publication date: 01 April 2006
Pages637–643Objective: The authors tested the hypothesis that concentrations of the pain-transmitting neuropeptide substance P are elevated in the CSF of patients with major depression or posttraumatic stress disorder (PTSD), which have overlapping ...
https://doi.org/10.1176/ajp.2006.163.4.637Publication date: 01 April 2006
Pages644–651Objective: In a cohort that spanned all of childhood and suffered equivalent types of traumas, the authors examined diagnostic validity and risk factors for posttraumatic stress disorder (PTSD). For older children, parent-child agreement was ...
https://doi.org/10.1176/ajp.2006.163.4.644Publication date: 01 April 2006
Pages652–658Objective: The aim of the present study was to examine the association between trauma and posttraumatic stress disorder (PTSD) and substance use disorders and to examine the correlates of substance use disorder plus PTSD comorbidity in the ...
https://doi.org/10.1176/ajp.2006.163.4.652Publication date: 01 April 2006
Pages659–666Objective: This study assessed the psychopathological effects of combat in veterans with and without combat stress reaction. Method: Veterans (N=214) from the 1982 Lebanon War were assessed in a prospective longitudinal ...
https://doi.org/10.1176/ajp.2006.163.4.659Publication date: 01 April 2006
Pages667–673Objective: The authors evaluated psychological responses to continuous terror. Method: Data were collected after 10 months of escalating hostilities against civilians in Israel. The study’s participants were randomly ...
https://doi.org/10.1176/ajp.2006.163.4.667Publication date: 01 April 2006
Pages674–681Studies imposing rigorous control over lifetime alcohol intake have usually not found smaller hippocampal volumes in persons with posttraumatic stress disorder. Because the majority of negative studies have used adolescent samples, it has been suggested ...
https://doi.org/10.1176/ajp.2006.163.4.674Publication date: 01 April 2006
Pages682–688Objective: Although previous studies of shorter duration have identified numerous risks and protective factors that powerfully influence outcomes in young adulthood and midlife, this long-term prospective study examines the effect of these ...
https://doi.org/10.1176/ajp.2006.163.4.682Publication date: 01 April 2006
Pages689–696Objective: The authors used the Psychiatric Research Interview for Substance and Mental Disorders for DSM-IV (PRISM-IV) to test the reliability of DSM-IV-defined disorders, including primary and substance-induced disorders, in substance-abusing ...
https://doi.org/10.1176/ajp.2006.163.4.689Publication date: 01 April 2006
Pages697–703Objective: The authors sought to expand on previous observations suggesting that body-image pathology is associated with illicit use of anabolic-androgenic steroids (AAS). In particular, the authors compared current versus past AAS users and ...
https://doi.org/10.1176/ajp.2006.163.4.697Publication date: 01 April 2006
Pages704–709Objective: This study attempted to determine whether lack of breast-feeding or a short duration of breast-feeding during infancy is associated with an elevated risk of hospitalization with alcohol-related diagnoses in adult life. ...
https://doi.org/10.1176/ajp.2006.163.4.704Publication date: 01 April 2006
Pages710–715Objective: Previous findings of excess brain lactate and delayed end-tidal CO 2 (pCO 2 ) recovery in subjects with panic disorder during hyperventilation suggested altered acid-base regulation. Two models ...
https://doi.org/10.1176/ajp.2006.163.4.710Publication date: 01 April 2006
Pages716–723Objective: Despite growing interest in adult attention deficit hyperactivity disorder (ADHD), little is known about its prevalence or correlates. Method: A screen for adult ADHD was included in a probability subsample (N=3,...
https://doi.org/10.1176/ajp.2006.163.4.716Publication date: 01 April 2006
Pages724–732Objective: For a proposed Medicare prospective payment system for inpatient psychiatric facility treatment, the authors developed a casemix classification to capture differences in patients’ real daily resource use. Method: ...
https://doi.org/10.1176/ajp.2006.163.4.724Brief Report
Publication date: 01 April 2006
Pages733–734Objective: This study investigated the association between the onset of psychiatric morbidity and separation from military service over a 10-year period (1991–2001). Method: The prevalence of affective, anxiety, somatic, and ...
https://doi.org/10.1176/ajp.2006.163.4.733Publication date: 01 April 2006
Pages735–738Objective: In controlled treatment trials, 40%–60% of unmedicated depressed individuals respond to cognitive behavior therapy (CBT). The authors examined whether pretreatment neural reactivity to emotional stimuli accounted for this variation. ...
https://doi.org/10.1176/ajp.2006.163.4.735Publication date: 01 April 2006
Pages738–740Objective: A previous laboratory-based study found elevated cortisol levels in anxious children susceptible to CO 2 -induced panic, but the effects of parent diagnosis were not considered. The current home-based study tested ...
https://doi.org/10.1176/ajp.2006.163.4.738Publication date: 01 April 2006
Pages740–742Objective: This study was carried out to confirm prior evidence of an effect of a single nucleotide polymorphism (SNP) in the metabotropic glutamate receptor 3 (GRM3) gene (a putative risk factor for schizophrenia) on measures of N ...
https://doi.org/10.1176/ajp.2006.163.4.740Publication date: 01 April 2006
Pages743–745Objective: The authors examined early onset of antipsychotic action and early prediction of nonresponse to antipsychotics in patients with first-episode schizophrenia. Method: Time to clinical response (≥20% improvement in ...
https://doi.org/10.1176/ajp.2006.163.4.743