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American Journal of Psychiatry

  • Volume 166
  • Number 2
  • February 2009

In This Issue

Editorial

Commentary

Treatment in Psychiatry

Images in Psychiatry

Reviews and Overviews

Publication date: 01 February 2009

Pages152–163

Objective: Whether there are differences in efficacy among second-generation antipsychotics in the treatment of schizophrenia is a matter of heated debate. The authors conducted a systematic review and meta-analysis of blinded studies comparing ...

https://doi.org/10.1176/appi.ajp.2008.08030368

Article

Publication date: 01 February 2009

Pages164–172

Objective: Treatment-emergent mania can have substantial negative impact on overall mood and psychosocial stability in patients receiving treatment for bipolar depression. This study examined the correlates associated with treatment-emergent ...

https://doi.org/10.1176/appi.ajp.2008.08030322

Publication date: 01 February 2009

Pages173–181

Objective: Little is known about how often bipolar depressive episodes are accompanied by subsyndromal manic symptoms in bipolar I and II disorders. The authors sought to determine the frequency and clinical correlates of manic symptoms during ...

https://doi.org/10.1176/appi.ajp.2008.08050746

Publication date: 01 February 2009

Pages182–188

Objective: Research that seeks to enroll noncompetent patients with Alzheimer’s disease without presenting any potential benefit to participants is the source of substantial ethical controversy. The authors used hypothetical Alzheimer’s disease ...

https://doi.org/10.1176/appi.ajp.2008.08050645

Publication date: 01 February 2009

Pages189–195

Objective: Cognitive deficits are prominent in schizophrenia. Patients have an average score one standard deviation below normal on a broad spectrum of cognitive tests. It has been repeatedly noted, however, that 20%–25% of patients differ from ...

https://doi.org/10.1176/appi.ajp.2008.08020258

Publication date: 01 February 2009

Pages216–225

Objective: Although amygdala dysfunction is reported in schizophrenia, it is unknown whether this deficit represents a heritable phenotype that is related to risk for schizophrenia or whether it is related to disease state. The purpose of the ...

https://doi.org/10.1176/appi.ajp.2008.08020261

Publication date: 01 February 2009

Pages226–233

Objective: Although olfactory deficits are common in schizophrenia, their underlying pathophysiology remains unknown. Recent evidence has suggested that cAMP signaling may be disrupted in schizophrenia. Since cAMP mediates signal transduction ...

https://doi.org/10.1176/appi.ajp.2008.07071210

Letters to the Editor

Correction

Letters to the Editor

Correction

Book Forum

Books Received

APA Official Actions

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