American Journal of Psychiatry
- Volume 167
- Number 10
- October 2010
In This Issue
Perspectives
Editorials
Perspectives
Commentary
Perspectives
APA Presidential Addresses
Perspectives
Treatment in Psychiatry
Perspectives
Reviews and Overviews
Publication date: 01 October 2010
Pages1178–1193The hippocampal formation is one of the most extensively studied regions of the brain, with well-described anatomy and basic physiology; moreover, aspects of human memory mediated by the hippocampus are well characterized. In schizophrenia, alterations in ...
https://doi.org/10.1176/appi.ajp.2010.09081187New Research
Articles
Publication date: 01 October 2010
Pages1194–1201Objective: There is growing clinical and epidemiologic evidence that major mood disorders form a spectrum from major depressive disorder to pure mania. The authors examined the prevalence and clinical correlates of major depressive disorder with ...
https://doi.org/10.1176/appi.ajp.2010.09071011Publication date: 01 October 2010
Pages1202–1209Objective: This study examined the effects of step therapy for antidepressants on prescription drug and other medical utilization and spending. Step therapy is a type of pharmaceutical benefit design that requires that patients try certain specified ...
https://doi.org/10.1176/appi.ajp.2010.09060877Publication date: 01 October 2010
Pages1210–1217Objective: The authors examined the impact of co-occurring posttraumatic stress disorder (PTSD) on women with borderline personality disorder who had attempted suicide in the preceding year. Method: Female borderline personality disorder outpatients (N=94) ...
https://doi.org/10.1176/appi.ajp.2010.09081213Publication date: 01 October 2010
Pages1218–1225Objective: Early pubertal timing in girls is associated with psychosocial problems throughout adolescence, but it is unclear whether these problems persist into young adulthood. The authors analyzed outcomes in adolescence and young adulthood in girls in a ...
https://doi.org/10.1176/appi.ajp.2010.09081190Publication date: 01 October 2010
Pages1226–1231Objective: Impaired function of the central gamma-aminobutyric acid (GABA) system, which provides the brain's major inhibitory pathways, is thought to play an important role in the pathophysiology of anxiety disorders. The effect of acute psychological ...
https://doi.org/10.1176/appi.ajp.2010.09070994Publication date: 01 October 2010
Pages1232–1239Objective: In recent years there has been a greater appreciation of the elevated prevalence of cardiovascular risk factors in the schizophrenia population and the liability some treatments have for their development. These vascular risk factors are in turn ...
https://doi.org/10.1176/appi.ajp.2010.09091328Publication date: 01 October 2010
Pages1240–1246Objective: Recent studies suggest a role for social factors during childhood in the later development of schizophrenia. Since social conditions in childhood are closely related to parental psychiatric illness, there is a need to disentangle how genes and ...
https://doi.org/10.1176/appi.ajp.2010.09010114Publication date: 01 October 2010
Pages1247–1253Objective: Prescriptions for anxiety medications have increased substantially in recent years. Individuals with anxiety disorders are at risk of nonmedical use of these medications, but information about whether this risk is elevated among patients with a ...
https://doi.org/10.1176/appi.ajp.2010.09081132Publication date: 01 October 2010
Pages1254–1263Objective: Family and twin studies indicate substantial overlap of genetic influences on psychotic and mood disorders. Linkage and candidate gene studies have also suggested overlap across schizophrenia, bipolar disorder, and major depressive disorder. The ...
https://doi.org/10.1176/appi.ajp.2010.09091335Publication date: 01 October 2010
Pages1264–1275Objective: Abnormal 50- and 100-msec event-related brain activity derived from paired-click procedures are well established in schizophrenia. There is little agreement on whether group differences in the ratio score, i.e., the ratio of EEG amplitude after ...
https://doi.org/10.1176/appi.ajp.2010.09071059