American Journal of Psychiatry

In the last third of the 20th century, the German psychiatrist Emil Kraepelin (1856–1926) became an icon of postpsychoanalytic medical-model psychiatry in the United States. His name became synonymous with a proto-biological, antipsychological, brain-...

https://doi.org/10.1176/appi.ajp.2015.15050665

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Extended-Release Guanfacine for Hyperactivity in Children With Autism Spectrum Disorder

Publication date: 28 August 2015

Pages1197–1206

Objective: Hyperactivity, impulsiveness, and distractibility are common problems in children with autism spectrum disorder (ASD). Extended-release guanfacine is approved for children with attention deficit hyperactivity disorder but not well studied in ...

https://doi.org/10.1176/appi.ajp.2015.15010055

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Preventing Onset of Anxiety Disorders in Offspring of Anxious Parents: A Randomized Controlled Trial of a Family-Based Intervention

Publication date: 25 September 2015

Pages1207–1214

Objective: The authors examined the efficacy of a family-based intervention to prevent the onset of anxiety disorders in offspring of anxious parents. Method: Participants were 136 families with a parent meeting DSM-IV criteria for an anxiety disorder and ...

https://doi.org/10.1176/appi.ajp.2015.14091178

The Brain’s Response to Reward Anticipation and Depression in Adolescence: Dimensionality, Specificity, and Longitudinal Predictions in a Community-Based Sample

Publication date: 18 June 2015

Pages1215–1223

Objective: The authors examined whether alterations in the brain’s reward network operate as a mechanism across the spectrum of risk for depression. They then tested whether these alterations are specific to anhedonia as compared with low mood and whether ...

https://doi.org/10.1176/appi.ajp.2015.14101298

Pregnancy Complications Following Prenatal Exposure to SSRIs or Maternal Psychiatric Disorders: Results From Population-Based National Register Data

Publication date: 04 August 2015

Pages1224–1232

Objective: Using national register data, the authors examined the relationship between prenatal selective serotonin reuptake inhibitor (SSRI) treatment and pregnancy complications, accounting for psychiatric diagnoses related to SSRI use. Method: This was a ...

https://doi.org/10.1176/appi.ajp.2015.14121575

Effect of Attention Training on Attention Bias Variability and PTSD Symptoms: Randomized Controlled Trials in Israeli and U.S. Combat Veterans

Publication date: 24 July 2015

Pages1233–1241

Objective: Attention allocation to threat is perturbed in patients with posttraumatic stress disorder (PTSD), with some studies indicating excess attention to threat and others indicating fluctuations between threat vigilance and threat avoidance. The ...

https://doi.org/10.1176/appi.ajp.2015.14121578

Threat-Related Attention Bias Variability and Posttraumatic Stress

Publication date: 24 July 2015

Pages1242–1250

Objective: Threat monitoring facilitates survival by allowing one to efficiently and accurately detect potential threats. Traumatic events can disrupt healthy threat monitoring, inducing biased and unstable threat-related attention deployment. Recent ...

https://doi.org/10.1176/appi.ajp.2015.14121579

Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Efficacy Results From a Randomized, Double-Blind, Placebo-Controlled Study

Publication date: 18 June 2015

Pages1251–1258

Objective: The authors sought to test the efficacy of adjunctive ziprasidone in adults with nonpsychotic unipolar major depression experiencing persistent symptoms after 8 weeks of open-label treatment with escitalopram. Method: This was an 8-week, ...

https://doi.org/10.1176/appi.ajp.2015.14101251