American Journal of Psychiatry

Objective: Psychosis or mania after childbirth is a psychiatric emergency with risk for suicide and infanticide. Method: The authors reviewed the epidemiologic and genetic research and physiological postpartum triggers (endocrine, immunological, circadian) ...

https://doi.org/10.1176/appi.ajp.2016.16040454

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Pain as a Predictor of Opioid Use Disorder in a Nationally Representative Sample

Publication date: 22 July 2016

Pages1189–1195

Objective: The authors sought to ascertain the relationship between moderate and more severe pain and prescription opioid use disorders in the noninstitutionalized U.S. population. Method: A structural equation model was used to assess prospectively the ...

https://doi.org/10.1176/appi.ajp.2016.15091179

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Early Improvement in Work Productivity Predicts Future Clinical Course in Depressed Outpatients: Findings From the CO-MED Trial

Publication date: 13 August 2016

Pages1196–1204

Objective: Depression symptom severity, the most commonly studied outcome in antidepressant treatment trials, accounts for only a small portion of burden related to major depression. While lost work productivity is the biggest contributor to depression’s ...

https://doi.org/10.1176/appi.ajp.2016.16020176

Efficacy of Quetiapine Monotherapy in Posttraumatic Stress Disorder: A Randomized, Placebo-Controlled Trial

Publication date: 15 July 2016

Pages1205–1212

Objective: This was a 12-week randomized, placebo-controlled trial to assess the efficacy of quetiapine monotherapy in the treatment of posttraumatic stress disorder (PTSD). Method: Eighty patients were randomly assigned to treatment with either quetiapine ...

https://doi.org/10.1176/appi.ajp.2016.15070967

A Diffusion Tensor Imaging Study in Children With ADHD, Autism Spectrum Disorder, OCD, and Matched Controls: Distinct and Non-Distinct White Matter Disruption and Dimensional Brain-Behavior Relationships

Publication date: 01 July 2016

Pages1213–1222

Objective: Neurodevelopmental disorders (NDDs) (attention deficit hyperactivity disorder [ADHD], autism spectrum disorder [ASD], and obsessive-compulsive disorder [OCD]) share genetic vulnerability and symptom domains. The authors present direct comparison ...

https://doi.org/10.1176/appi.ajp.2016.15111435

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Blunted Neural Response to Rewards as a Prospective Predictor of the Development of Depression in Adolescent Girls

Publication date: 01 July 2016

Pages1223–1230

Objective: A blunted neural response to rewards has recently emerged as a potential mechanistic biomarker of adolescent depression. The reward positivity, an event-related potential elicited by feedback indicating monetary gain relative to loss, has been ...

https://doi.org/10.1176/appi.ajp.2016.15121524

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A Longitudinal Study of Adjustment Disorder After Trauma Exposure

Publication date: 24 October 2016

Pages1231–1238

Objective: Adjustment disorder has been recategorized as a trauma- and stressor-related disorder in DSM-5. The aim of this study was to determine the prevalence of adjustment disorder in the first 12 months after severe injury; to determine whether ...

https://doi.org/10.1176/appi.ajp.2016.16010071